Compile Data Set for Download or QSAR

Found 60 hits Enz. Inhib. hit(s) with all data for entry = 50012496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557933 (CHEMBL4634333) Show SMILES Cc1scc2c1N(C(=O)CN1CCN(CCCCCCCCCCNC(=O)Cc3ccc4N5CCC6OC7CC[N+]8=C(C7=CC6=C5C(C)(C)c4c3)C(C)(C)c3cc(ccc83)S([O-])(=O)=O)CC1)c1ccccc1NC2=O |c:41,44,47| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557933 (CHEMBL4634333) Show SMILES Cc1scc2c1N(C(=O)CN1CCN(CCCCCCCCCCNC(=O)Cc3ccc4N5CCC6OC7CC[N+]8=C(C7=CC6=C5C(C)(C)c4c3)C(C)(C)c3cc(ccc83)S([O-])(=O)=O)CC1)c1ccccc1NC2=O |c:41,44,47| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557935 (CHEMBL4756833) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c3ccc(cc3oc2c1)=[N+](C)C |(23.6,-21.33,;22.26,-20.56,;22.26,-19.02,;20.92,-21.33,;19.58,-20.56,;20.92,-22.88,;19.58,-22.1,;29.3,-11.33,;27.96,-10.56,;27.96,-9.01,;26.63,-11.33,;25.29,-10.56,;26.63,-12.87,;25.28,-12.09,;30.23,-17.55,;28.9,-16.78,;28.9,-15.24,;27.56,-17.55,;26.22,-16.78,;27.56,-19.1,;26.21,-18.32,;23.52,-4.8,;21.98,-4.8,;21.2,-3.47,;21.2,-6.14,;19.66,-6.14,;18.9,-7.48,;19.66,-8.8,;18.88,-10.13,;17.34,-10.11,;16.58,-8.76,;15.03,-8.75,;14.26,-10.09,;15.02,-11.44,;16.56,-11.44,;17.33,-12.78,;16.55,-14.1,;18.65,-13.54,;12.71,-10.08,;11.93,-11.41,;11.94,-8.74,;12.73,-7.4,;11.96,-6.06,;10.42,-6.05,;9.65,-4.72,;8.12,-4.71,;7.34,-6.03,;5.8,-6.02,;5.03,-7.35,;5.78,-8.68,;5.01,-10.01,;5.76,-11.35,;4.99,-12.67,;5.74,-14,;7.28,-14.02,;8.03,-15.36,;9.57,-15.38,;10.35,-14.05,;10.32,-16.72,;9.45,-17.98,;7.96,-17.63,;6.91,-18.74,;7.35,-20.21,;8.84,-20.56,;9.88,-19.45,;11.31,-20.02,;12.65,-19.27,;13.91,-20.15,;12.89,-17.75,;14.39,-17.42,;14.85,-15.94,;13.8,-14.81,;12.3,-15.15,;11.84,-16.62,;8.06,-12.69,;7.3,-11.35,;8.1,-7.37,;9.64,-7.38,;19.64,-11.47,;18.86,-12.8,;19.62,-14.13,;21.17,-14.14,;21.95,-12.82,;21.19,-11.48,;21.98,-10.15,;21.2,-8.81,;21.98,-7.47,;21.94,-15.48,;21.16,-16.82,;23.49,-15.49,)| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50230694 (CHEMBL295388) Show SMILES CCN(CC)CCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1 Show InChI InChI=1S/C28H38N4O2/c1-3-30(4-2)18-10-9-11-22-16-19-31(20-17-22)21-27(33)32-25-14-7-5-12-23(25)28(34)29-24-13-6-8-15-26(24)32/h5-8,12-15,22H,3-4,9-11,16-21H2,1-2H3,(H,29,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M2 receptor (unknown origin) expressed in A9 cells by scintillation counting analysis				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50557939 (CHEMBL4742721) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(\C=C\c3ccc(OCC(=O)NCCCCCC(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc67)CC5)cn4)cc3)=[N+]12 |c:29,t:27,99| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.417	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557934 (CHEMBL4794548) Show SMILES Cc1scc2c1N(C(=O)CN1CCN(CCCCCCCCCCNC(=O)c3ccc(c(c3)C(O)=O)-c3c4ccc(N)c(c4oc4c(c(=N)ccc34)S(O)(=O)=O)S(O)(=O)=O)CC1)c1ccccc1NC2=O |(36.93,-9.73,;38.19,-8.84,;39.64,-9.34,;40.57,-8.11,;39.69,-6.85,;38.21,-7.3,;36.93,-6.44,;35.6,-7.21,;35.6,-8.75,;34.27,-6.44,;32.93,-7.21,;32.93,-8.75,;31.6,-9.52,;30.26,-8.75,;28.93,-9.52,;27.6,-8.76,;26.27,-9.53,;24.93,-8.77,;23.6,-9.54,;22.26,-8.77,;20.93,-9.55,;19.6,-8.78,;18.27,-9.56,;16.93,-8.79,;15.6,-9.57,;15.6,-11.12,;16.95,-11.89,;14.27,-11.9,;12.92,-11.13,;11.59,-11.91,;11.58,-13.46,;12.93,-14.23,;14.27,-13.46,;12.93,-15.78,;14.27,-16.56,;12.51,-17.27,;10.25,-14.22,;10.25,-15.77,;11.58,-16.55,;11.58,-18.09,;10.24,-18.86,;10.23,-20.41,;8.9,-18.09,;8.9,-16.54,;7.56,-15.76,;7.57,-14.21,;6.26,-13.45,;6.26,-11.92,;4.92,-11.13,;7.59,-11.14,;8.92,-11.93,;8.91,-13.46,;4.91,-14.21,;3.57,-13.44,;5.74,-15.5,;4.13,-15.54,;7.54,-18.84,;6.22,-18.07,;8.31,-20.18,;6.77,-20.18,;30.26,-7.21,;31.6,-6.44,;36.83,-4.92,;35.36,-4.47,;35.01,-2.98,;36.14,-1.92,;37.61,-2.37,;37.95,-3.87,;39.48,-4.08,;40.24,-5.42,;41.78,-5.3,)| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50538317 (CHEMBL4636083) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.NCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 Show InChI InChI=1S/C30H42N6O2/c31-14-18-34-21-19-33(20-22-34)15-6-5-7-24-12-16-35(17-13-24)23-29(37)36-27-10-3-1-8-25(27)30(38)32-26-9-2-4-11-28(26)36/h1-4,8-11,24H,5-7,12-23,31H2,(H,32,38)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50538319 (CHEMBL4645845) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.NCCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)cn1 Show InChI InChI=1S/C32H41N7O3/c33-16-17-34-30(40)13-12-25-21-38(23-35-25)18-6-5-7-24-14-19-37(20-15-24)22-31(41)39-28-10-3-1-8-26(28)32(42)36-27-9-2-4-11-29(27)39/h1-4,8-11,21,23-24H,5-7,12-20,22,33H2,(H,34,40)(H,36,42)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557939 (CHEMBL4742721) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(\C=C\c3ccc(OCC(=O)NCCCCCC(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc67)CC5)cn4)cc3)=[N+]12 |c:29,t:27,99| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557937 (CHEMBL4754371) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c(C)c2)cc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557936 (CHEMBL4748004) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.955	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50557935 (CHEMBL4756833) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c3ccc(cc3oc2c1)=[N+](C)C |(23.6,-21.33,;22.26,-20.56,;22.26,-19.02,;20.92,-21.33,;19.58,-20.56,;20.92,-22.88,;19.58,-22.1,;29.3,-11.33,;27.96,-10.56,;27.96,-9.01,;26.63,-11.33,;25.29,-10.56,;26.63,-12.87,;25.28,-12.09,;30.23,-17.55,;28.9,-16.78,;28.9,-15.24,;27.56,-17.55,;26.22,-16.78,;27.56,-19.1,;26.21,-18.32,;23.52,-4.8,;21.98,-4.8,;21.2,-3.47,;21.2,-6.14,;19.66,-6.14,;18.9,-7.48,;19.66,-8.8,;18.88,-10.13,;17.34,-10.11,;16.58,-8.76,;15.03,-8.75,;14.26,-10.09,;15.02,-11.44,;16.56,-11.44,;17.33,-12.78,;16.55,-14.1,;18.65,-13.54,;12.71,-10.08,;11.93,-11.41,;11.94,-8.74,;12.73,-7.4,;11.96,-6.06,;10.42,-6.05,;9.65,-4.72,;8.12,-4.71,;7.34,-6.03,;5.8,-6.02,;5.03,-7.35,;5.78,-8.68,;5.01,-10.01,;5.76,-11.35,;4.99,-12.67,;5.74,-14,;7.28,-14.02,;8.03,-15.36,;9.57,-15.38,;10.35,-14.05,;10.32,-16.72,;9.45,-17.98,;7.96,-17.63,;6.91,-18.74,;7.35,-20.21,;8.84,-20.56,;9.88,-19.45,;11.31,-20.02,;12.65,-19.27,;13.91,-20.15,;12.89,-17.75,;14.39,-17.42,;14.85,-15.94,;13.8,-14.81,;12.3,-15.15,;11.84,-16.62,;8.06,-12.69,;7.3,-11.35,;8.1,-7.37,;9.64,-7.38,;19.64,-11.47,;18.86,-12.8,;19.62,-14.13,;21.17,-14.14,;21.95,-12.82,;21.19,-11.48,;21.98,-10.15,;21.2,-8.81,;21.98,-7.47,;21.94,-15.48,;21.16,-16.82,;23.49,-15.49,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.977	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557939 (CHEMBL4742721) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(\C=C\c3ccc(OCC(=O)NCCCCCC(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc67)CC5)cn4)cc3)=[N+]12 |c:29,t:27,99| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557938 (CHEMBL4744233) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)cn1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557934 (CHEMBL4794548) Show SMILES Cc1scc2c1N(C(=O)CN1CCN(CCCCCCCCCCNC(=O)c3ccc(c(c3)C(O)=O)-c3c4ccc(N)c(c4oc4c(c(=N)ccc34)S(O)(=O)=O)S(O)(=O)=O)CC1)c1ccccc1NC2=O |(36.93,-9.73,;38.19,-8.84,;39.64,-9.34,;40.57,-8.11,;39.69,-6.85,;38.21,-7.3,;36.93,-6.44,;35.6,-7.21,;35.6,-8.75,;34.27,-6.44,;32.93,-7.21,;32.93,-8.75,;31.6,-9.52,;30.26,-8.75,;28.93,-9.52,;27.6,-8.76,;26.27,-9.53,;24.93,-8.77,;23.6,-9.54,;22.26,-8.77,;20.93,-9.55,;19.6,-8.78,;18.27,-9.56,;16.93,-8.79,;15.6,-9.57,;15.6,-11.12,;16.95,-11.89,;14.27,-11.9,;12.92,-11.13,;11.59,-11.91,;11.58,-13.46,;12.93,-14.23,;14.27,-13.46,;12.93,-15.78,;14.27,-16.56,;12.51,-17.27,;10.25,-14.22,;10.25,-15.77,;11.58,-16.55,;11.58,-18.09,;10.24,-18.86,;10.23,-20.41,;8.9,-18.09,;8.9,-16.54,;7.56,-15.76,;7.57,-14.21,;6.26,-13.45,;6.26,-11.92,;4.92,-11.13,;7.59,-11.14,;8.92,-11.93,;8.91,-13.46,;4.91,-14.21,;3.57,-13.44,;5.74,-15.5,;4.13,-15.54,;7.54,-18.84,;6.22,-18.07,;8.31,-20.18,;6.77,-20.18,;30.26,-7.21,;31.6,-6.44,;36.83,-4.92,;35.36,-4.47,;35.01,-2.98,;36.14,-1.92,;37.61,-2.37,;37.95,-3.87,;39.48,-4.08,;40.24,-5.42,;41.78,-5.3,)| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557940 (CHEMBL4789147) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c3ccc(cc3oc2c1)=[N+](C)C |(55.74,-15.63,;54.4,-14.86,;54.4,-13.32,;53.06,-15.63,;51.72,-14.86,;53.06,-17.18,;51.71,-16.4,;49.39,-15,;48.05,-14.23,;48.05,-12.68,;46.71,-15,;45.36,-14.23,;46.71,-16.54,;45.36,-15.77,;69.03,-5.05,;67.69,-4.29,;67.69,-2.75,;66.36,-5.06,;65.03,-4.3,;63.7,-5.07,;63.69,-6.61,;62.36,-7.38,;61.03,-6.61,;61.04,-5.07,;59.71,-4.29,;58.37,-5.06,;58.37,-6.61,;59.7,-7.37,;59.7,-8.91,;58.37,-9.68,;60.09,-10.4,;57.04,-4.29,;57.04,-2.75,;55.7,-5.06,;54.37,-4.29,;53.03,-5.05,;51.7,-4.28,;50.37,-5.05,;50.36,-6.59,;49.03,-4.28,;47.7,-5.05,;47.7,-6.59,;46.45,-7.49,;46.93,-8.95,;46.14,-10.28,;44.61,-10.27,;43.82,-11.6,;42.28,-11.58,;41.5,-12.91,;39.97,-12.89,;39.19,-14.21,;39.94,-15.56,;39.15,-16.88,;37.61,-16.86,;36.86,-15.52,;36.83,-18.19,;37.67,-19.46,;39.17,-19.12,;40.22,-20.26,;39.75,-21.74,;38.25,-22.07,;37.21,-20.93,;35.69,-21.52,;34.45,-20.7,;33.17,-21.55,;34.23,-19.17,;32.74,-18.82,;32.3,-17.35,;33.35,-16.22,;34.85,-16.58,;35.29,-18.05,;41.48,-15.57,;42.27,-14.25,;48.47,-8.96,;48.95,-7.49,;62.36,-8.92,;61.02,-9.68,;61.01,-11.22,;62.36,-12,;63.69,-11.23,;63.69,-9.69,;65.03,-8.93,;65.03,-7.39,;66.37,-6.61,;62.36,-13.54,;61.02,-14.31,;63.69,-14.31,)| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50230694 (CHEMBL295388) Show SMILES CCN(CC)CCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1 Show InChI InChI=1S/C28H38N4O2/c1-3-30(4-2)18-10-9-11-22-16-19-31(20-17-22)21-27(33)32-25-14-7-5-12-23(25)28(34)29-24-13-6-8-15-26(24)32/h5-8,12-15,22H,3-4,9-11,16-21H2,1-2H3,(H,29,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M4 receptor (unknown origin) expressed in NG108-15 cells by scintillation counting analysis				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50557938 (CHEMBL4744233) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557935 (CHEMBL4756833) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c3ccc(cc3oc2c1)=[N+](C)C |(23.6,-21.33,;22.26,-20.56,;22.26,-19.02,;20.92,-21.33,;19.58,-20.56,;20.92,-22.88,;19.58,-22.1,;29.3,-11.33,;27.96,-10.56,;27.96,-9.01,;26.63,-11.33,;25.29,-10.56,;26.63,-12.87,;25.28,-12.09,;30.23,-17.55,;28.9,-16.78,;28.9,-15.24,;27.56,-17.55,;26.22,-16.78,;27.56,-19.1,;26.21,-18.32,;23.52,-4.8,;21.98,-4.8,;21.2,-3.47,;21.2,-6.14,;19.66,-6.14,;18.9,-7.48,;19.66,-8.8,;18.88,-10.13,;17.34,-10.11,;16.58,-8.76,;15.03,-8.75,;14.26,-10.09,;15.02,-11.44,;16.56,-11.44,;17.33,-12.78,;16.55,-14.1,;18.65,-13.54,;12.71,-10.08,;11.93,-11.41,;11.94,-8.74,;12.73,-7.4,;11.96,-6.06,;10.42,-6.05,;9.65,-4.72,;8.12,-4.71,;7.34,-6.03,;5.8,-6.02,;5.03,-7.35,;5.78,-8.68,;5.01,-10.01,;5.76,-11.35,;4.99,-12.67,;5.74,-14,;7.28,-14.02,;8.03,-15.36,;9.57,-15.38,;10.35,-14.05,;10.32,-16.72,;9.45,-17.98,;7.96,-17.63,;6.91,-18.74,;7.35,-20.21,;8.84,-20.56,;9.88,-19.45,;11.31,-20.02,;12.65,-19.27,;13.91,-20.15,;12.89,-17.75,;14.39,-17.42,;14.85,-15.94,;13.8,-14.81,;12.3,-15.15,;11.84,-16.62,;8.06,-12.69,;7.3,-11.35,;8.1,-7.37,;9.64,-7.38,;19.64,-11.47,;18.86,-12.8,;19.62,-14.13,;21.17,-14.14,;21.95,-12.82,;21.19,-11.48,;21.98,-10.15,;21.2,-8.81,;21.98,-7.47,;21.94,-15.48,;21.16,-16.82,;23.49,-15.49,)| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50557936 (CHEMBL4748004) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557941 (CHEMBL4650998) Show SMILES CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c(C)c2)cc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50557940 (CHEMBL4789147) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c3ccc(cc3oc2c1)=[N+](C)C |(55.74,-15.63,;54.4,-14.86,;54.4,-13.32,;53.06,-15.63,;51.72,-14.86,;53.06,-17.18,;51.71,-16.4,;49.39,-15,;48.05,-14.23,;48.05,-12.68,;46.71,-15,;45.36,-14.23,;46.71,-16.54,;45.36,-15.77,;69.03,-5.05,;67.69,-4.29,;67.69,-2.75,;66.36,-5.06,;65.03,-4.3,;63.7,-5.07,;63.69,-6.61,;62.36,-7.38,;61.03,-6.61,;61.04,-5.07,;59.71,-4.29,;58.37,-5.06,;58.37,-6.61,;59.7,-7.37,;59.7,-8.91,;58.37,-9.68,;60.09,-10.4,;57.04,-4.29,;57.04,-2.75,;55.7,-5.06,;54.37,-4.29,;53.03,-5.05,;51.7,-4.28,;50.37,-5.05,;50.36,-6.59,;49.03,-4.28,;47.7,-5.05,;47.7,-6.59,;46.45,-7.49,;46.93,-8.95,;46.14,-10.28,;44.61,-10.27,;43.82,-11.6,;42.28,-11.58,;41.5,-12.91,;39.97,-12.89,;39.19,-14.21,;39.94,-15.56,;39.15,-16.88,;37.61,-16.86,;36.86,-15.52,;36.83,-18.19,;37.67,-19.46,;39.17,-19.12,;40.22,-20.26,;39.75,-21.74,;38.25,-22.07,;37.21,-20.93,;35.69,-21.52,;34.45,-20.7,;33.17,-21.55,;34.23,-19.17,;32.74,-18.82,;32.3,-17.35,;33.35,-16.22,;34.85,-16.58,;35.29,-18.05,;41.48,-15.57,;42.27,-14.25,;48.47,-8.96,;48.95,-7.49,;62.36,-8.92,;61.02,-9.68,;61.01,-11.22,;62.36,-12,;63.69,-11.23,;63.69,-9.69,;65.03,-8.93,;65.03,-7.39,;66.37,-6.61,;62.36,-13.54,;61.02,-14.31,;63.69,-14.31,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50230694 (CHEMBL295388) Show SMILES CCN(CC)CCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1 Show InChI InChI=1S/C28H38N4O2/c1-3-30(4-2)18-10-9-11-22-16-19-31(20-17-22)21-27(33)32-25-14-7-5-12-23(25)28(34)29-24-13-6-8-15-26(24)32/h5-8,12-15,22H,3-4,9-11,16-21H2,1-2H3,(H,29,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M1 receptor (unknown origin) expressed in A9 cells by scintillation counting analysis				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50557937 (CHEMBL4754371) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c(C)c2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557936 (CHEMBL4748004) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557937 (CHEMBL4754371) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c(C)c2)cc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557940 (CHEMBL4789147) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c3ccc(cc3oc2c1)=[N+](C)C |(55.74,-15.63,;54.4,-14.86,;54.4,-13.32,;53.06,-15.63,;51.72,-14.86,;53.06,-17.18,;51.71,-16.4,;49.39,-15,;48.05,-14.23,;48.05,-12.68,;46.71,-15,;45.36,-14.23,;46.71,-16.54,;45.36,-15.77,;69.03,-5.05,;67.69,-4.29,;67.69,-2.75,;66.36,-5.06,;65.03,-4.3,;63.7,-5.07,;63.69,-6.61,;62.36,-7.38,;61.03,-6.61,;61.04,-5.07,;59.71,-4.29,;58.37,-5.06,;58.37,-6.61,;59.7,-7.37,;59.7,-8.91,;58.37,-9.68,;60.09,-10.4,;57.04,-4.29,;57.04,-2.75,;55.7,-5.06,;54.37,-4.29,;53.03,-5.05,;51.7,-4.28,;50.37,-5.05,;50.36,-6.59,;49.03,-4.28,;47.7,-5.05,;47.7,-6.59,;46.45,-7.49,;46.93,-8.95,;46.14,-10.28,;44.61,-10.27,;43.82,-11.6,;42.28,-11.58,;41.5,-12.91,;39.97,-12.89,;39.19,-14.21,;39.94,-15.56,;39.15,-16.88,;37.61,-16.86,;36.86,-15.52,;36.83,-18.19,;37.67,-19.46,;39.17,-19.12,;40.22,-20.26,;39.75,-21.74,;38.25,-22.07,;37.21,-20.93,;35.69,-21.52,;34.45,-20.7,;33.17,-21.55,;34.23,-19.17,;32.74,-18.82,;32.3,-17.35,;33.35,-16.22,;34.85,-16.58,;35.29,-18.05,;41.48,-15.57,;42.27,-14.25,;48.47,-8.96,;48.95,-7.49,;62.36,-8.92,;61.02,-9.68,;61.01,-11.22,;62.36,-12,;63.69,-11.23,;63.69,-9.69,;65.03,-8.93,;65.03,-7.39,;66.37,-6.61,;62.36,-13.54,;61.02,-14.31,;63.69,-14.31,)| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557938 (CHEMBL4744233) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)cn1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50557941 (CHEMBL4650998) Show SMILES CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c(C)c2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50557939 (CHEMBL4742721) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(\C=C\c3ccc(OCC(=O)NCCCCCC(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc67)CC5)cn4)cc3)=[N+]12 |c:29,t:27,99| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50230694 (CHEMBL295388) Show SMILES CCN(CC)CCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1 Show InChI InChI=1S/C28H38N4O2/c1-3-30(4-2)18-10-9-11-22-16-19-31(20-17-22)21-27(33)32-25-14-7-5-12-23(25)28(34)29-24-13-6-8-15-26(24)32/h5-8,12-15,22H,3-4,9-11,16-21H2,1-2H3,(H,29,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M3 receptor (unknown origin) expressed in A9 cells by scintillation counting analysis				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557941 (CHEMBL4650998) Show SMILES CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c(C)c2)cc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50557939 (CHEMBL4742721) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(\C=C\c3ccc(OCC(=O)NCCCCCC(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc67)CC5)cn4)cc3)=[N+]12 |c:29,t:27,99| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50557938 (CHEMBL4744233) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)cn1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50557942 (CHEMBL4780759) Show SMILES F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(CCC(=O)NCCCCC(=O)NCCCN3CCN(CC(=O)N4c5ccccc5NC(=O)c5cccnc45)CC3)=[N+]12 |c:17,t:15,63| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-QNB from truncated EGFP-fused human muscarinic M1 receptor expressed in HEK293 cells by UV-visible spectroscopy				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50557936 (CHEMBL4748004) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50557938 (CHEMBL4744233) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50557937 (CHEMBL4754371) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c(C)c2)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50557935 (CHEMBL4756833) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c3ccc(cc3oc2c1)=[N+](C)C |(23.6,-21.33,;22.26,-20.56,;22.26,-19.02,;20.92,-21.33,;19.58,-20.56,;20.92,-22.88,;19.58,-22.1,;29.3,-11.33,;27.96,-10.56,;27.96,-9.01,;26.63,-11.33,;25.29,-10.56,;26.63,-12.87,;25.28,-12.09,;30.23,-17.55,;28.9,-16.78,;28.9,-15.24,;27.56,-17.55,;26.22,-16.78,;27.56,-19.1,;26.21,-18.32,;23.52,-4.8,;21.98,-4.8,;21.2,-3.47,;21.2,-6.14,;19.66,-6.14,;18.9,-7.48,;19.66,-8.8,;18.88,-10.13,;17.34,-10.11,;16.58,-8.76,;15.03,-8.75,;14.26,-10.09,;15.02,-11.44,;16.56,-11.44,;17.33,-12.78,;16.55,-14.1,;18.65,-13.54,;12.71,-10.08,;11.93,-11.41,;11.94,-8.74,;12.73,-7.4,;11.96,-6.06,;10.42,-6.05,;9.65,-4.72,;8.12,-4.71,;7.34,-6.03,;5.8,-6.02,;5.03,-7.35,;5.78,-8.68,;5.01,-10.01,;5.76,-11.35,;4.99,-12.67,;5.74,-14,;7.28,-14.02,;8.03,-15.36,;9.57,-15.38,;10.35,-14.05,;10.32,-16.72,;9.45,-17.98,;7.96,-17.63,;6.91,-18.74,;7.35,-20.21,;8.84,-20.56,;9.88,-19.45,;11.31,-20.02,;12.65,-19.27,;13.91,-20.15,;12.89,-17.75,;14.39,-17.42,;14.85,-15.94,;13.8,-14.81,;12.3,-15.15,;11.84,-16.62,;8.06,-12.69,;7.3,-11.35,;8.1,-7.37,;9.64,-7.38,;19.64,-11.47,;18.86,-12.8,;19.62,-14.13,;21.17,-14.14,;21.95,-12.82,;21.19,-11.48,;21.98,-10.15,;21.2,-8.81,;21.98,-7.47,;21.94,-15.48,;21.16,-16.82,;23.49,-15.49,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50557937 (CHEMBL4754371) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c(C)c2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50557936 (CHEMBL4748004) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50557940 (CHEMBL4789147) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c3ccc(cc3oc2c1)=[N+](C)C |(55.74,-15.63,;54.4,-14.86,;54.4,-13.32,;53.06,-15.63,;51.72,-14.86,;53.06,-17.18,;51.71,-16.4,;49.39,-15,;48.05,-14.23,;48.05,-12.68,;46.71,-15,;45.36,-14.23,;46.71,-16.54,;45.36,-15.77,;69.03,-5.05,;67.69,-4.29,;67.69,-2.75,;66.36,-5.06,;65.03,-4.3,;63.7,-5.07,;63.69,-6.61,;62.36,-7.38,;61.03,-6.61,;61.04,-5.07,;59.71,-4.29,;58.37,-5.06,;58.37,-6.61,;59.7,-7.37,;59.7,-8.91,;58.37,-9.68,;60.09,-10.4,;57.04,-4.29,;57.04,-2.75,;55.7,-5.06,;54.37,-4.29,;53.03,-5.05,;51.7,-4.28,;50.37,-5.05,;50.36,-6.59,;49.03,-4.28,;47.7,-5.05,;47.7,-6.59,;46.45,-7.49,;46.93,-8.95,;46.14,-10.28,;44.61,-10.27,;43.82,-11.6,;42.28,-11.58,;41.5,-12.91,;39.97,-12.89,;39.19,-14.21,;39.94,-15.56,;39.15,-16.88,;37.61,-16.86,;36.86,-15.52,;36.83,-18.19,;37.67,-19.46,;39.17,-19.12,;40.22,-20.26,;39.75,-21.74,;38.25,-22.07,;37.21,-20.93,;35.69,-21.52,;34.45,-20.7,;33.17,-21.55,;34.23,-19.17,;32.74,-18.82,;32.3,-17.35,;33.35,-16.22,;34.85,-16.58,;35.29,-18.05,;41.48,-15.57,;42.27,-14.25,;48.47,-8.96,;48.95,-7.49,;62.36,-8.92,;61.02,-9.68,;61.01,-11.22,;62.36,-12,;63.69,-11.23,;63.69,-9.69,;65.03,-8.93,;65.03,-7.39,;66.37,-6.61,;62.36,-13.54,;61.02,-14.31,;63.69,-14.31,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50557941 (CHEMBL4650998) Show SMILES CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c(C)c2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50557935 (CHEMBL4756833) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c3ccc(cc3oc2c1)=[N+](C)C |(23.6,-21.33,;22.26,-20.56,;22.26,-19.02,;20.92,-21.33,;19.58,-20.56,;20.92,-22.88,;19.58,-22.1,;29.3,-11.33,;27.96,-10.56,;27.96,-9.01,;26.63,-11.33,;25.29,-10.56,;26.63,-12.87,;25.28,-12.09,;30.23,-17.55,;28.9,-16.78,;28.9,-15.24,;27.56,-17.55,;26.22,-16.78,;27.56,-19.1,;26.21,-18.32,;23.52,-4.8,;21.98,-4.8,;21.2,-3.47,;21.2,-6.14,;19.66,-6.14,;18.9,-7.48,;19.66,-8.8,;18.88,-10.13,;17.34,-10.11,;16.58,-8.76,;15.03,-8.75,;14.26,-10.09,;15.02,-11.44,;16.56,-11.44,;17.33,-12.78,;16.55,-14.1,;18.65,-13.54,;12.71,-10.08,;11.93,-11.41,;11.94,-8.74,;12.73,-7.4,;11.96,-6.06,;10.42,-6.05,;9.65,-4.72,;8.12,-4.71,;7.34,-6.03,;5.8,-6.02,;5.03,-7.35,;5.78,-8.68,;5.01,-10.01,;5.76,-11.35,;4.99,-12.67,;5.74,-14,;7.28,-14.02,;8.03,-15.36,;9.57,-15.38,;10.35,-14.05,;10.32,-16.72,;9.45,-17.98,;7.96,-17.63,;6.91,-18.74,;7.35,-20.21,;8.84,-20.56,;9.88,-19.45,;11.31,-20.02,;12.65,-19.27,;13.91,-20.15,;12.89,-17.75,;14.39,-17.42,;14.85,-15.94,;13.8,-14.81,;12.3,-15.15,;11.84,-16.62,;8.06,-12.69,;7.3,-11.35,;8.1,-7.37,;9.64,-7.38,;19.64,-11.47,;18.86,-12.8,;19.62,-14.13,;21.17,-14.14,;21.95,-12.82,;21.19,-11.48,;21.98,-10.15,;21.2,-8.81,;21.98,-7.47,;21.94,-15.48,;21.16,-16.82,;23.49,-15.49,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50557940 (CHEMBL4789147) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c3ccc(cc3oc2c1)=[N+](C)C |(55.74,-15.63,;54.4,-14.86,;54.4,-13.32,;53.06,-15.63,;51.72,-14.86,;53.06,-17.18,;51.71,-16.4,;49.39,-15,;48.05,-14.23,;48.05,-12.68,;46.71,-15,;45.36,-14.23,;46.71,-16.54,;45.36,-15.77,;69.03,-5.05,;67.69,-4.29,;67.69,-2.75,;66.36,-5.06,;65.03,-4.3,;63.7,-5.07,;63.69,-6.61,;62.36,-7.38,;61.03,-6.61,;61.04,-5.07,;59.71,-4.29,;58.37,-5.06,;58.37,-6.61,;59.7,-7.37,;59.7,-8.91,;58.37,-9.68,;60.09,-10.4,;57.04,-4.29,;57.04,-2.75,;55.7,-5.06,;54.37,-4.29,;53.03,-5.05,;51.7,-4.28,;50.37,-5.05,;50.36,-6.59,;49.03,-4.28,;47.7,-5.05,;47.7,-6.59,;46.45,-7.49,;46.93,-8.95,;46.14,-10.28,;44.61,-10.27,;43.82,-11.6,;42.28,-11.58,;41.5,-12.91,;39.97,-12.89,;39.19,-14.21,;39.94,-15.56,;39.15,-16.88,;37.61,-16.86,;36.86,-15.52,;36.83,-18.19,;37.67,-19.46,;39.17,-19.12,;40.22,-20.26,;39.75,-21.74,;38.25,-22.07,;37.21,-20.93,;35.69,-21.52,;34.45,-20.7,;33.17,-21.55,;34.23,-19.17,;32.74,-18.82,;32.3,-17.35,;33.35,-16.22,;34.85,-16.58,;35.29,-18.05,;41.48,-15.57,;42.27,-14.25,;48.47,-8.96,;48.95,-7.49,;62.36,-8.92,;61.02,-9.68,;61.01,-11.22,;62.36,-12,;63.69,-11.23,;63.69,-9.69,;65.03,-8.93,;65.03,-7.39,;66.37,-6.61,;62.36,-13.54,;61.02,-14.31,;63.69,-14.31,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	275	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50557941 (CHEMBL4650998) Show SMILES CN(C)c1ccc(\C=C\C=C\c2cc(C)[n+](CCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c(C)c2)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	389	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50557935 (CHEMBL4756833) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCN3CCN(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)CC3)c3ccc(cc3oc2c1)=[N+](C)C |(23.6,-21.33,;22.26,-20.56,;22.26,-19.02,;20.92,-21.33,;19.58,-20.56,;20.92,-22.88,;19.58,-22.1,;29.3,-11.33,;27.96,-10.56,;27.96,-9.01,;26.63,-11.33,;25.29,-10.56,;26.63,-12.87,;25.28,-12.09,;30.23,-17.55,;28.9,-16.78,;28.9,-15.24,;27.56,-17.55,;26.22,-16.78,;27.56,-19.1,;26.21,-18.32,;23.52,-4.8,;21.98,-4.8,;21.2,-3.47,;21.2,-6.14,;19.66,-6.14,;18.9,-7.48,;19.66,-8.8,;18.88,-10.13,;17.34,-10.11,;16.58,-8.76,;15.03,-8.75,;14.26,-10.09,;15.02,-11.44,;16.56,-11.44,;17.33,-12.78,;16.55,-14.1,;18.65,-13.54,;12.71,-10.08,;11.93,-11.41,;11.94,-8.74,;12.73,-7.4,;11.96,-6.06,;10.42,-6.05,;9.65,-4.72,;8.12,-4.71,;7.34,-6.03,;5.8,-6.02,;5.03,-7.35,;5.78,-8.68,;5.01,-10.01,;5.76,-11.35,;4.99,-12.67,;5.74,-14,;7.28,-14.02,;8.03,-15.36,;9.57,-15.38,;10.35,-14.05,;10.32,-16.72,;9.45,-17.98,;7.96,-17.63,;6.91,-18.74,;7.35,-20.21,;8.84,-20.56,;9.88,-19.45,;11.31,-20.02,;12.65,-19.27,;13.91,-20.15,;12.89,-17.75,;14.39,-17.42,;14.85,-15.94,;13.8,-14.81,;12.3,-15.15,;11.84,-16.62,;8.06,-12.69,;7.3,-11.35,;8.1,-7.37,;9.64,-7.38,;19.64,-11.47,;18.86,-12.8,;19.62,-14.13,;21.17,-14.14,;21.95,-12.82,;21.19,-11.48,;21.98,-10.15,;21.2,-8.81,;21.98,-7.47,;21.94,-15.48,;21.16,-16.82,;23.49,-15.49,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50557940 (CHEMBL4789147) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c3ccc(cc3oc2c1)=[N+](C)C |(55.74,-15.63,;54.4,-14.86,;54.4,-13.32,;53.06,-15.63,;51.72,-14.86,;53.06,-17.18,;51.71,-16.4,;49.39,-15,;48.05,-14.23,;48.05,-12.68,;46.71,-15,;45.36,-14.23,;46.71,-16.54,;45.36,-15.77,;69.03,-5.05,;67.69,-4.29,;67.69,-2.75,;66.36,-5.06,;65.03,-4.3,;63.7,-5.07,;63.69,-6.61,;62.36,-7.38,;61.03,-6.61,;61.04,-5.07,;59.71,-4.29,;58.37,-5.06,;58.37,-6.61,;59.7,-7.37,;59.7,-8.91,;58.37,-9.68,;60.09,-10.4,;57.04,-4.29,;57.04,-2.75,;55.7,-5.06,;54.37,-4.29,;53.03,-5.05,;51.7,-4.28,;50.37,-5.05,;50.36,-6.59,;49.03,-4.28,;47.7,-5.05,;47.7,-6.59,;46.45,-7.49,;46.93,-8.95,;46.14,-10.28,;44.61,-10.27,;43.82,-11.6,;42.28,-11.58,;41.5,-12.91,;39.97,-12.89,;39.19,-14.21,;39.94,-15.56,;39.15,-16.88,;37.61,-16.86,;36.86,-15.52,;36.83,-18.19,;37.67,-19.46,;39.17,-19.12,;40.22,-20.26,;39.75,-21.74,;38.25,-22.07,;37.21,-20.93,;35.69,-21.52,;34.45,-20.7,;33.17,-21.55,;34.23,-19.17,;32.74,-18.82,;32.3,-17.35,;33.35,-16.22,;34.85,-16.58,;35.29,-18.05,;41.48,-15.57,;42.27,-14.25,;48.47,-8.96,;48.95,-7.49,;62.36,-8.92,;61.02,-9.68,;61.01,-11.22,;62.36,-12,;63.69,-11.23,;63.69,-9.69,;65.03,-8.93,;65.03,-7.39,;66.37,-6.61,;62.36,-13.54,;61.02,-14.31,;63.69,-14.31,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50557936 (CHEMBL4748004) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.Cc1cc(\C=C\c2cc3CCCN4CCCc(c2)c34)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50557939 (CHEMBL4742721) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(\C=C\c3ccc(OCC(=O)NCCCCCC(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc67)CC5)cn4)cc3)=[N+]12 |c:29,t:27,99| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...				Citation and Details Article DOI: 10.1039/d0md00137f BindingDB Entry DOI: 10.7270/Q2ZS316G
					More data for this Ligand-Target Pair

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