Compile Data Set for Download or QSAR

Found 31 hits Enz. Inhib. hit(s) with all data for entry = 50012937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 (unknown origin) transfected in dog MDCK cells assessed as inhibition of [14C]uric acid uptake by liquid scintillation counting m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561689 (Dotinurad | Fyu-981) Show SMILES Oc1c(Cl)cc(cc1Cl)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human URAT1 expressed in Xenopus laevis oocytes assessed as inhibition of [14C]uric acid uptake measured after 60 mins by liquid scinti...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2C9 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human URAT1 expressed in Xenopus laevis oocytes assessed as inhibition of [14C]uric acid uptake measured after 60 mins by liquid scinti...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50342279 ((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-be...) Show SMILES CCc1oc2cc(O)ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI InChI=1S/C17H12Br2O4/c1-2-13-15(10-4-3-9(20)7-14(10)23-13)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,20,22H,2H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 (unknown origin) transfected in dog MDCK cells assessed as inhibition of [14C]uric acid uptake by liquid scintillation counting m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561676 (CHEMBL4762461) Show SMILES Oc1ccc(cc1C#N)C(=O)N1CCc2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561694 (CHEMBL4748804) Show SMILES Oc1c(Cl)cc(cc1C(F)(F)F)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561692 (CHEMBL4749075) Show SMILES Oc1c(cc(cc1C#N)C(=O)N1CS(=O)(=O)c2ccccc12)C#C Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561698 (CHEMBL4792097) Show SMILES COc1cc(cc(Cl)c1O)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561678 (CHEMBL4796932) Show SMILES Oc1c(I)cc(cc1C#N)C(=O)N1CCc2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561696 (CHEMBL4760971) Show SMILES CSc1cc(cc(Cl)c1O)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561689 (Dotinurad | Fyu-981) Show SMILES Oc1c(Cl)cc(cc1Cl)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561693 (CHEMBL4756915) Show SMILES CSc1cc(cc(C#N)c1O)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561682 (CHEMBL4796568) Show SMILES Oc1c(cc(cc1C1CC1)C(=O)N1CCc2ccccc12)C#N Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561675 (CHEMBL4781629) Show SMILES Cc1c(C)c2ccccc2n1C(=O)c1ccc(O)c(c1)C#N Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561687 (CHEMBL4744184) Show SMILES Oc1c(cc(cc1C(F)(F)F)C(=O)N1CSc2ccccc12)C#N Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561683 (CHEMBL4744854) Show SMILES Oc1c(Cl)cc(cc1C#N)C(=O)N1CCc2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561697 (CHEMBL4762003) Show SMILES COc1cc(cc(c1O)C(F)(F)F)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561685 (CHEMBL4740995) Show SMILES Oc1c(cc(cc1C1CC1)C(=O)N1CS(=O)(=O)c2ccccc12)C#N Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561681 (CHEMBL4753182) Show SMILES CC(C)(C)c1cc(cc(C#N)c1O)C(=O)N1CCc2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561695 (CHEMBL4778323) Show SMILES Oc1c(F)cc(cc1Cl)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50561685 (CHEMBL4740995) Show SMILES Oc1c(cc(cc1C1CC1)C(=O)N1CS(=O)(=O)c2ccccc12)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2C9 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561690 (CHEMBL4781818) Show SMILES CC(C)c1cc(cc(C#N)c1O)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561679 (CHEMBL4757464) Show SMILES Oc1c(cc(cc1C#N)C(=O)N1CCc2ccccc12)C#N Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561691 (CHEMBL4790389) Show SMILES CCc1cc(cc(C#N)c1O)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561680 (CHEMBL4785752) Show SMILES CSc1cc(cc(C#N)c1O)C(=O)N1CCc2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561686 (CHEMBL4756625) Show SMILES Oc1c(cc(cc1C(F)(F)F)C(=O)N1CS(=O)(=O)c2ccccc12)C#N Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561677 (CHEMBL4782683) Show SMILES COc1cc(cc(C#N)c1O)C(=O)N1CCc2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561688 (CHEMBL4785815) Show SMILES Oc1c(Cl)cc(cc1C#N)C(=O)N1CS(=O)(=O)c2ccccc12 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561684 (CHEMBL4800504) Show SMILES Oc1c(cc(cc1C(F)(F)F)C(=O)N1CCc2ccccc12)C#N Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and i...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
					More data for this Ligand-Target Pair