BindingDB PrimarySearch

Found 40 hits Enz. Inhib. hit(s) with all data for entry = 50012952
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561775 (CHEMBL4792696) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561773 (CHEMBL4751330) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM25045 (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561771 (CHEMBL4764755) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561776 (CHEMBL4759291) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561777 (CHEMBL4758082) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50436459 (CHEMBL2396661) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PI3Kalpha (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561778 (CHEMBL4793846) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561772 (CHEMBL4748452) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561769 (CHEMBL4740323) Show SMILES O=C(Nc1ccccc1)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561774 (CHEMBL4740384) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561779 (CHEMBL4754159) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM25045 (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561780 (CHEMBL4749535) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561782 (CHEMBL4794335) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519385 (SAR-245409 \| SAR245409 \| Voxtalisib \| XL-765 \| XL7...) Show SMILES CCn1c2nc(N)nc(C)c2cc(-c2cc[nH]n2)c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PI3Kalpha (unknown origin) using phosphatidylinositol as substrate in presence of ATP by luciferase-luciferin-coupled chemiluminescence...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561779 (CHEMBL4754159) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561773 (CHEMBL4751330) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561776 (CHEMBL4759291) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561771 (CHEMBL4764755) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561767 (CHEMBL4760858) Show SMILES CNC(=O)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561780 (CHEMBL4749535) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561768 (CHEMBL4753544) Show SMILES OCCNC(=O)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561781 (CHEMBL4742886) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561777 (CHEMBL4758082) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561775 (CHEMBL4792696) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561770 (CHEMBL4751402) Show SMILES O=C(Nc1cncnc1)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561770 (CHEMBL4751402) Show SMILES O=C(Nc1cncnc1)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50519385 (SAR-245409 \| SAR245409 \| Voxtalisib \| XL-765 \| XL7...) Show SMILES CCn1c2nc(N)nc(C)c2cc(-c2cc[nH]n2)c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mTOR (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561772 (CHEMBL4748452) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561768 (CHEMBL4753544) Show SMILES OCCNC(=O)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561767 (CHEMBL4760858) Show SMILES CNC(=O)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561778 (CHEMBL4793846) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561774 (CHEMBL4740384) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	243	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561769 (CHEMBL4740323) Show SMILES O=C(Nc1ccccc1)Nc1nc(N2CCOCC2)c2ccccc2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	504	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50207169 (4-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561765 (CHEMBL4799984) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50561766 (CHEMBL4793551) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50207169 (4-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50561766 (CHEMBL4793551) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00289 BindingDB Entry DOI: 10.7270/Q2DF6VXJ
TBA					More data for this Ligand-Target Pair