Found 75 hits Enz. Inhib. hit(s) with all data for entry = 50013143 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50257829
(2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)...)Show InChI InChI=1S/C17H23IN4O4/c1-9(2)11-4-14(25-3)12(18)5-13(11)26-15-6-20-17(22-16(15)19)21-10(7-23)8-24/h4-6,9-10,23-24H,7-8H2,1-3H3,(H3,19,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183138
(US9150546, I-291 | US9688643, I-291 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C22H21ClFN5O3/c1-14(2)32-19-9-8-17(12-18(19)24)26-20-27-21(30)28(11-3-10-25)22(31)29(20)13-15-4-6-16(23)7-5-15/h4-9,12,14H,3,11,13H2,1-2H3,(H,26,27,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183166
(US9150546, I-326 | US9688643, I-326 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCCNC(C)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C24H27ClFN5O4/c1-15(2)35-21-10-9-19(13-20(21)26)28-22-29-23(33)30(12-4-11-27-16(3)32)24(34)31(22)14-17-5-7-18(25)8-6-17/h5-10,13,15H,4,11-12,14H2,1-3H3,(H,27,32)(H,28,29,33) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183191
(US9150546, I-355 | US9688643, I-355 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl Show InChI InChI=1S/C22H22Cl2N4O5/c1-13(2)33-18-8-7-16(11-17(18)24)25-20-26-21(31)27(10-9-19(29)30)22(32)28(20)12-14-3-5-15(23)6-4-14/h3-8,11,13H,9-10,12H2,1-2H3,(H,29,30)(H,25,26,31) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183184
(US9150546, I-348 | US9688643, I-348 | US9718790, I...)Show SMILES CCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C22H24ClFN4O3/c1-4-11-27-21(29)26-20(25-17-9-10-19(18(24)12-17)31-14(2)3)28(22(27)30)13-15-5-7-16(23)8-6-15/h5-10,12,14H,4,11,13H2,1-3H3,(H,25,26,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183132
(US9150546, I-285 | US9688643, I-285 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C22H24ClFN4O4/c1-14(2)32-19-9-8-17(12-18(19)24)25-20-26-21(30)27(10-3-11-29)22(31)28(20)13-15-4-6-16(23)7-5-15/h4-9,12,14,29H,3,10-11,13H2,1-2H3,(H,25,26,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563052
(CHEMBL4748113)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC(O)=O)c(=O)n2Cc2ccc(C)cc2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183201
(US9150546, I-365 | US9688643, I-365 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C23H26ClFN4O4/c1-15(2)33-20-10-9-18(13-19(20)25)26-21-27-22(31)28(11-3-4-12-30)23(32)29(21)14-16-5-7-17(24)8-6-16/h5-10,13,15,30H,3-4,11-12,14H2,1-2H3,(H,26,27,31) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183266
(US9150546, I-434 | US9688643, I-434 | US9718790, I...)Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CC(O)=O)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C21H20Cl2N4O5/c1-12(2)32-17-8-7-15(9-16(17)23)24-19-25-20(30)27(11-18(28)29)21(31)26(19)10-13-3-5-14(22)6-4-13/h3-9,12H,10-11H2,1-2H3,(H,28,29)(H,24,25,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183145
(US9150546, I-298 | US9688643, I-298 | US9718790, I...)Show SMILES CNC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C23H25ClFN5O4/c1-14(2)34-19-9-8-17(12-18(19)25)27-21-28-22(32)29(11-10-20(31)26-3)23(33)30(21)13-15-4-6-16(24)7-5-15/h4-9,12,14H,10-11,13H2,1-3H3,(H,26,31)(H,27,28,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183200
(US9150546, I-364 | US9688643, I-364 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)C(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C24H26ClFN4O5/c1-14(2)35-19-10-9-17(11-18(19)26)27-21-28-22(33)30(13-24(3,4)20(31)32)23(34)29(21)12-15-5-7-16(25)8-6-15/h5-11,14H,12-13H2,1-4H3,(H,31,32)(H,27,28,33) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183097
(US9150546, I-228 | US9688643, I-228 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl Show InChI InChI=1S/C22H24Cl2N4O3/c1-13(2)28-21(29)26-20(25-17-9-10-19(18(24)11-17)31-14(3)4)27(22(28)30)12-15-5-7-16(23)8-6-15/h5-11,13-14H,12H2,1-4H3,(H,25,26,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183139
(US9150546, I-292 | US9688643, I-292 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCNC(C)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C23H25ClFN5O4/c1-14(2)34-20-9-8-18(12-19(20)25)27-21-28-22(32)29(11-10-26-15(3)31)23(33)30(21)13-16-4-6-17(24)7-5-16/h4-9,12,14H,10-11,13H2,1-3H3,(H,26,31)(H,27,28,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563048
(CHEMBL4789094)Show SMILES CC(C)Oc1ccc(Nc2cc(=O)n(CCC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183121
(US9150546, I-273 | US9688643, I-273 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C21H22ClFN4O4/c1-13(2)31-18-8-7-16(11-17(18)23)24-19-25-20(29)26(9-10-28)21(30)27(19)12-14-3-5-15(22)6-4-14/h3-8,11,13,28H,9-10,12H2,1-2H3,(H,24,25,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183125
(US9150546, I-277 | US9688643, I-277 | US9718790, I...)Show SMILES CCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C21H22ClFN4O3/c1-4-26-20(28)25-19(24-16-9-10-18(17(23)11-16)30-13(2)3)27(21(26)29)12-14-5-7-15(22)8-6-14/h5-11,13H,4,12H2,1-3H3,(H,24,25,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183107
(US9150546, I-244 | US9688643, I-244 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C22H24ClFN4O3/c1-13(2)28-21(29)26-20(25-17-9-10-19(18(24)11-17)31-14(3)4)27(22(28)30)12-15-5-7-16(23)8-6-15/h5-11,13-14H,12H2,1-4H3,(H,25,26,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 2/3
(Homo sapiens (Human)) | BDBM50257829
(2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)...)Show InChI InChI=1S/C17H23IN4O4/c1-9(2)11-4-14(25-3)12(18)5-13(11)26-15-6-20-17(22-16(15)19)21-10(7-23)8-24/h4-6,9-10,23-24H,7-8H2,1-3H3,(H3,19,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X2/3 receptor |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183146
(US9150546, I-299 | US9688643, I-299 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C22H23ClFN5O4/c1-13(2)33-18-8-7-16(11-17(18)24)26-20-27-21(31)28(10-9-19(25)30)22(32)29(20)12-14-3-5-15(23)6-4-14/h3-8,11,13H,9-10,12H2,1-2H3,(H2,25,30)(H,26,27,31) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183148
(US9150546, I-301 | US9688643, I-301 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(Cc3ccccc3)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C26H24ClFN4O3/c1-17(2)35-23-13-12-21(14-22(23)28)29-24-30-25(33)32(16-18-6-4-3-5-7-18)26(34)31(24)15-19-8-10-20(27)11-9-19/h3-14,17H,15-16H2,1-2H3,(H,29,30,33) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183136
(US9150546, I-289 | US9688643, I-289 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C22H22ClFN4O5/c1-13(2)33-18-8-7-16(11-17(18)24)25-20-26-21(31)27(10-9-19(29)30)22(32)28(20)12-14-3-5-15(23)6-4-14/h3-8,11,13H,9-10,12H2,1-2H3,(H,29,30)(H,25,26,31) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183199
(US9150546, I-363 | US9688643, I-363 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCCC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C23H24ClFN4O5/c1-14(2)34-19-10-9-17(12-18(19)25)26-21-27-22(32)28(11-3-4-20(30)31)23(33)29(21)13-15-5-7-16(24)8-6-15/h5-10,12,14H,3-4,11,13H2,1-2H3,(H,30,31)(H,26,27,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183160
(US9150546, I-320 | US9688643, I-320 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H23ClN4O4/c1-14(2)30-18-9-7-17(8-10-18)23-19-24-20(28)25(11-12-27)21(29)26(19)13-15-3-5-16(22)6-4-15/h3-10,14,27H,11-13H2,1-2H3,(H,23,24,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183135
(US9150546, I-288 | US9688643, I-288 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C21H19ClFN5O3/c1-13(2)31-18-8-7-16(11-17(18)23)25-19-26-20(29)27(10-9-24)21(30)28(19)12-14-3-5-15(22)6-4-14/h3-8,11,13H,10,12H2,1-2H3,(H,25,26,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183089
(US9150546, I-200 | US9688643, I-200 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C22H25ClN4O3/c1-14(2)27-21(28)25-20(24-18-9-11-19(12-10-18)30-15(3)4)26(22(27)29)13-16-5-7-17(23)8-6-16/h5-12,14-15H,13H2,1-4H3,(H,24,25,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50413382
(CHEMBL494833)Show InChI InChI=1S/C15H20N4O3/c1-8(2)9-5-11(20-3)12(21-4)6-10(9)22-13-7-18-15(17)19-14(13)16/h5-8H,1-4H3,(H4,16,17,18,19) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563041
(CHEMBL4746334)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2-c2ccc(Cl)s2)cc1F | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 144 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563036
(CHEMBL4787960)Show SMILES CCn1c(=O)nc(Nc2ccc(OC(C)C)cc2)n(Cc2ccc(Cl)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 149 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563049
(CHEMBL4752152)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)c(CC(O)=O)cn2Cc2ccc(Cl)cc2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 152 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183143
(US9150546, I-296 | US9688643, I-296 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C21H20ClFN4O4/c1-12(2)31-18-9-8-16(10-17(18)23)24-19-25-20(29)27(13(3)28)21(30)26(19)11-14-4-6-15(22)7-5-14/h4-10,12H,11H2,1-3H3,(H,24,25,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 176 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563050
(CHEMBL4796811)Show SMILES CC(C)Oc1ccc(Nc2ncc(CC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 219 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183070
(US9150546, I-020 | US9688643, I-020 | US9718790, I...)Show SMILES CC(C)n1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C20H18ClF3N4O2/c1-12(2)28-18(29)26-17(25-16-5-3-4-14(10-16)20(22,23)24)27(19(28)30)11-13-6-8-15(21)9-7-13/h3-10,12H,11H2,1-2H3,(H,25,26,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 389 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183117
(US9150546, I-269 | US9688643, I-269 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)[nH]c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C19H18ClFN4O3/c1-11(2)28-16-8-7-14(9-15(16)21)22-17-23-18(26)24-19(27)25(17)10-12-3-5-13(20)6-4-12/h3-9,11H,10H2,1-2H3,(H2,22,23,24,26,27) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 415 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183110
(US9150546, I-248 | US9688643, I-248 | US9718790, I...)Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H21ClN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183106
(US9150546, I-243 | US9688643, I-243 | US9718790, I...)Show SMILES COc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl Show InChI InChI=1S/C20H20Cl2N4O3/c1-12(2)26-19(27)24-18(23-15-8-9-17(29-3)16(22)10-15)25(20(26)28)11-13-4-6-14(21)7-5-13/h4-10,12H,11H2,1-3H3,(H,23,24,27) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183112
(US9150546, I-255 | US9688643, I-255 | US9718790, I...)Show SMILES CC(C)NC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C23H26ClN5O3/c1-14(2)25-20(30)17-7-11-19(12-8-17)26-21-27-22(31)29(15(3)4)23(32)28(21)13-16-5-9-18(24)10-6-16/h5-12,14-15H,13H2,1-4H3,(H,25,30)(H,26,27,31) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563051
(CHEMBL4788581)Show SMILES CC(C)Oc1ccc(Nc2nc(CC(O)=O)nc(=O)n2Cc2ccc(Cl)cc2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 614 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183131
(US9150546, I-284 | US9688643, I-284 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C21H20ClFN4O5/c1-12(2)32-17-8-7-15(9-16(17)23)24-19-25-20(30)27(11-18(28)29)21(31)26(19)10-13-3-5-14(22)6-4-13/h3-9,12H,10-11H2,1-2H3,(H,28,29)(H,24,25,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 629 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM183103
(US9150546, I-240 | US9688643, I-240)Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C25H22Cl2N4O3/c1-16(2)31-24(32)29-23(30(25(31)33)15-17-8-10-18(26)11-9-17)28-19-12-13-22(21(27)14-19)34-20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,28,29,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 953 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563037
(CHEMBL4797969)Show SMILES CCn1c(=O)nc(Cc2ccc(OC(C)C)cc2)n(Cc2ccc(Cl)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563035
(CHEMBL4778429)Show SMILES CC(C)Oc1ccc(cc1)C(=O)Nc1nc(=O)n(C(C)C)c(=O)n1Cc1ccc(Cl)cc1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563053
(CHEMBL4749540)Show SMILES COc1ccc(Cn2c(Nc3cccc(c3)C(F)(F)F)nc(=O)n(CC=C)c2=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 2/3
(Homo sapiens (Human)) | BDBM183200
(US9150546, I-364 | US9688643, I-364 | US9718790, I...)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)C(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C24H26ClFN4O5/c1-14(2)35-19-10-9-17(11-18(19)26)27-21-28-22(33)30(13-24(3,4)20(31)32)23(34)29(21)12-15-5-7-16(25)8-6-15/h5-11,14H,12-13H2,1-4H3,(H,31,32)(H,27,28,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X2/3 receptor |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 2/3
(Homo sapiens (Human)) | BDBM50563052
(CHEMBL4748113)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CCC(O)=O)c(=O)n2Cc2ccc(C)cc2)cc1Cl | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X2/3 receptor |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563045
(CHEMBL4797152)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2-c2ccc(Cl)cc2)cc1F | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563044
(CHEMBL4743578)Show SMILES COc1ccc(cc1)-n1c(Nc2ccc(OC(C)C)c(F)c2)nc(=O)n(C(C)C)c1=O | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563043
(CHEMBL4759101)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2CC2CC2)cc1F | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563047
(CHEMBL4750833)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2CC(=O)N2CCOCC2)cc1F | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563040
(CHEMBL4757743)Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)[nH]2)cc1F | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
P2X purinoceptor 3
(Homo sapiens (Human)) | BDBM50563039
(CHEMBL4746738)Show SMILES CC(C)n1c(=O)nc(Nc2ccc(cc2)C(O)=O)n(Cc2ccc(Cl)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cells |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127833
BindingDB Entry DOI: 10.7270/Q2V40ZXF |
More data for this
Ligand-Target Pair | |
Search and Browse
