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TargetP2X purinoceptor 3
LigandBDBM50413382
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2081414 (CHEMBL4737205)
IC50 136±n/a nM
Citation Kai, HHoriguchi, TKameyama, TAsahi, KEndoh, TJikihara, SHasegawa, TTanaka, SNozu, ATakeyama, CTomari, MTakahashi, FTamura, NYagi, SItoh, TIsou, Y Dioxotriazine derivatives as a new class of P2X Bioorg Med Chem Lett37:0 (2021) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 3
Name:P2X purinoceptor 3
Synonyms:ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa
Type:Protein
Mol. Mass.:44292.02
Organism:Homo sapiens (Human)
Description:P56373
Residue:397
Sequence:
MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
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  Blast E-value cutoff:
BDBM50413382
n/a
NameBDBM50413382
Synonyms:CHEMBL494833
TypeSmall organic molecule
Emp. Form.C15H20N4O3
Mol. Mass.304.3443
SMILESCOc1cc(Oc2cnc(N)nc2N)c(cc1OC)C(C)C
Structure
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