Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50013658 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50011502
(CHEMBL3261926)Show SMILES NC1(CCOCC1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| Show InChI InChI=1S/C22H22N4O2/c23-14-17-3-7-19(8-4-17)18-5-1-16(2-6-18)13-20(15-24)26-21(27)22(25)9-11-28-12-10-22/h1-8,20H,9-13,25H2,(H,26,27)/t20-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568317
(CHEMBL4865824)Show SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50011502
(CHEMBL3261926)Show SMILES NC1(CCOCC1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| Show InChI InChI=1S/C22H22N4O2/c23-14-17-3-7-19(8-4-17)18-5-1-16(2-6-18)13-20(15-24)26-21(27)22(25)9-11-28-12-10-22/h1-8,20H,9-13,25H2,(H,26,27)/t20-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of cellular cathepsin C (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568319
(CHEMBL4869673)Show SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(c(c1)C#N)S(C)(=O)=O)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568314
(CHEMBL4856217)Show SMILES [H][C@@]12CCC[C@]1([H])N[C@@H](C2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568310
(CHEMBL4875554)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CC2(CCCC2)CN1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568318
(CHEMBL4850769)Show SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(C#N)c(c1)S(C)(=O)=O)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568309
(CHEMBL4864151)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CC2(CCC2)CN1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568316
(CHEMBL4869840)Show SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568310
(CHEMBL4875554)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CC2(CCCC2)CN1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of cellular cathepsin C (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568308
(CHEMBL4851884)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CC2(CC2)CN1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568313
(CHEMBL4854705)Show SMILES [H][C@]12CCC[C@@]1([H])N[C@@H](C2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568313
(CHEMBL4854705)Show SMILES [H][C@]12CCC[C@@]1([H])N[C@@H](C2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of cellular cathepsin C (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50502617
(CHEMBL4570759)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CCCN1 |r| Show InChI InChI=1S/C21H20N4O/c22-13-16-5-9-18(10-6-16)17-7-3-15(4-8-17)12-19(14-23)25-21(26)20-2-1-11-24-20/h3-10,19-20,24H,1-2,11-12H2,(H,25,26)/t19-,20-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568309
(CHEMBL4864151)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CC2(CCC2)CN1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of cellular cathepsin C (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568315
(CHEMBL4876996)Show SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568312
(CHEMBL4848266)Show SMILES [H][C@@]12C[C@]1([H])N[C@@H](C2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 223 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568311
(CHEMBL4849657)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CC2(CN1)CCCCC2 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568306
(CHEMBL4846681)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1COCCN1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 308 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568307
(CHEMBL4847757)Show SMILES [H][C@@]12CCCN1C[C@@H](NC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 394 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568314
(CHEMBL4856217)Show SMILES [H][C@@]12CCC[C@]1([H])N[C@@H](C2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 699 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of cellular cathepsin C (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568320
(CHEMBL4860749)Show SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc2oc(=O)n(C)c2c1)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human cathepsin C |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568315
(CHEMBL4876996)Show SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of cellular cathepsin C (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50568306
(CHEMBL4846681)Show SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1COCCN1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of cellular cathepsin C (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128202 BindingDB Entry DOI: 10.7270/Q2PR80R9 |
More data for this Ligand-Target Pair | |