BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50014220
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 \| NSC_3019 \| diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50139705 (4-Nitro-3-(4-nitro-phenyl)-5-trifluoromethyl-1H-py...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50139708 (3-(4-Nitro-phenyl)-5-trifluoromethyl-1H-pyrazole \|...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50139704 (3-(2,4-Difluoro-phenyl)-4-nitro-5-trifluoromethyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50139709 (3-(2,4-Bis-trifluoromethyl-phenyl)-4-nitro-5-trifl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50139707 (4-Nitro-3-(4-nitro-phenyl)-5-trifluoromethyl-isoxa...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50139706 (3-(2,4-Dinitro-phenyl)-4-nitro-5-trifluoromethyl-1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50139710 (4-Nitro-3-phenyl-5-trifluoromethyl-1H-pyrazole \| C...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
GlaxoSmithKline Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair