Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157077![]() (CHEMBL184982 | {(R)-4-[(4R,10aS,12aR)-4-Hydroxy-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157075![]() (2-[(4R)-4-[(2S,18R)-6-{2-[(6,7-dimethoxy-1,2,3,4-t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157079![]() (CHEMBL182301 | [(R)-4-((4R,10aS,12aR)-4-Hydroxy-10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157074![]() (CHEMBL182671 | {(R)-4-[(4R,10aS,12aR)-4-Hydroxy-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157072![]() (CHEMBL367757 | {(R)-4-[(10aS,12aR)-8-(3-Hydroxy-be...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157076![]() (CHEMBL185033 | {(R)-4-[(10aS,12aR)-8-(2-Hydroxy-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157072![]() (CHEMBL367757 | {(R)-4-[(10aS,12aR)-8-(3-Hydroxy-be...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157074![]() (CHEMBL182671 | {(R)-4-[(4R,10aS,12aR)-4-Hydroxy-8-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157079![]() (CHEMBL182301 | [(R)-4-((4R,10aS,12aR)-4-Hydroxy-10...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157078![]() (CHEMBL185179 | [(R)-4-((10aS,12aR)-10a,12a-Dimethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157080![]() (2-[(4R)-4-[(2S,12R,18R)-12-hydroxy-6-[(3-{[(2S)-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157081![]() (CHEMBL179911 | {(R)-4-[(4R,10aS,12S,12aR)-4,12-Dih...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157077![]() (CHEMBL184982 | {(R)-4-[(4R,10aS,12aR)-4-Hydroxy-8-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157075![]() (2-[(4R)-4-[(2S,18R)-6-{2-[(6,7-dimethoxy-1,2,3,4-t...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157078![]() (CHEMBL185179 | [(R)-4-((10aS,12aR)-10a,12a-Dimethy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157073![]() (2-[(4R)-4-[(2S,18R)-6-[(3-{[(2S)-2-(6-methoxynapht...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157076![]() (CHEMBL185033 | {(R)-4-[(10aS,12aR)-8-(2-Hydroxy-et...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157081![]() (CHEMBL179911 | {(R)-4-[(4R,10aS,12S,12aR)-4,12-Dih...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157080![]() (2-[(4R)-4-[(2S,12R,18R)-12-hydroxy-6-[(3-{[(2S)-2-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50157073![]() (2-[(4R)-4-[(2S,18R)-6-[(3-{[(2S)-2-(6-methoxynapht...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
XenoPort Inc. Curated by ChEMBL | Assay Description In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cells | Bioorg Med Chem Lett 15: 85-7 (2004) Article DOI: 10.1016/j.bmcl.2004.10.027 BindingDB Entry DOI: 10.7270/Q2VT1RKR | |||||||||||
More data for this Ligand-Target Pair |