Found 106 hits Enz. Inhib. hit(s) with all data for entry = 50016686 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50172000
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-phenoxy]-...)Show SMILES OC(=O)C1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(F)(F)F Show InChI InChI=1S/C21H17ClF6O5/c22-15-8-12(10-20(23,24)25)2-4-17(15)32-7-1-6-31-14-3-5-16-13(9-14)11-19(33-16,18(29)30)21(26,27)28/h2-5,8-9H,1,6-7,10-11H2,(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 399 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50172001
(5-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-propoxy]...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(cc3Cl)C(F)(F)F)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O5/c1-2-20(19(26)27)12-13-10-15(5-7-17(13)30-20)28-8-3-9-29-18-6-4-14(11-16(18)22)21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 834 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50172002
(6-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy...)Show SMILES CCC1(Cc2ccc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)cc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-2-20(19(26)27)12-13-4-5-14(11-18(13)31-20)28-8-3-9-29-17-7-6-15(10-16(17)22)30-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171996
(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)Show SMILES CCCc1cc(SC(F)(F)F)ccc1OCCCOc1ccc2OC(CC)(Cc2c1)C(O)=O Show InChI InChI=1S/C24H27F3O5S/c1-3-6-16-14-19(33-24(25,26)27)8-10-20(16)31-12-5-11-30-18-7-9-21-17(13-18)15-23(4-2,32-21)22(28)29/h7-10,13-14H,3-6,11-12,15H2,1-2H3,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172002
(6-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy...)Show SMILES CCC1(Cc2ccc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)cc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-2-20(19(26)27)12-13-4-5-14(11-18(13)31-20)28-8-3-9-29-17-7-6-15(10-16(17)22)30-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171991
(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(cc3Cl)C(C)(C)C)ccc2O1)C(O)=O Show InChI InChI=1S/C24H29ClO5/c1-5-24(22(26)27)15-16-13-18(8-10-20(16)30-24)28-11-6-12-29-21-9-7-17(14-19(21)25)23(2,3)4/h7-10,13-14H,5-6,11-12,15H2,1-4H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171996
(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)Show SMILES CCCc1cc(SC(F)(F)F)ccc1OCCCOc1ccc2OC(CC)(Cc2c1)C(O)=O Show InChI InChI=1S/C24H27F3O5S/c1-3-6-16-14-19(33-24(25,26)27)8-10-20(16)31-12-5-11-30-18-7-9-21-17(13-18)15-23(4-2,32-21)22(28)29/h7-10,13-14H,3-6,11-12,15H2,1-2H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171997
(5-{3-[2-Chloro-4-(2,2-dimethyl-propyl)-phenoxy]-pr...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(CC(C)(C)C)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C25H31ClO5/c1-5-25(23(27)28)16-18-14-19(8-10-21(18)31-25)29-11-6-12-30-22-9-7-17(13-20(22)26)15-24(2,3)4/h7-10,13-14H,5-6,11-12,15-16H2,1-4H3,(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171993
(5-[3-(2-Chloro-4-trifluoromethylsulfanyl-phenoxy)-...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(SC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O5S/c1-2-20(19(26)27)12-13-10-14(4-6-17(13)30-20)28-8-3-9-29-18-7-5-15(11-16(18)22)31-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171999
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES CC1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-20(19(26)27)11-13-9-14(3-5-17(13)31-20)28-7-2-8-29-18-6-4-15(10-16(18)22)30-12-21(23,24)25/h3-6,9-10H,2,7-8,11-12H2,1H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171993
(5-[3-(2-Chloro-4-trifluoromethylsulfanyl-phenoxy)-...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(SC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O5S/c1-2-20(19(26)27)12-13-10-14(4-6-17(13)30-20)28-8-3-9-29-18-7-5-15(11-16(18)22)31-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171994
((R)-5-[3-(2-Chloro-5-trifluoromethyl-phenoxy)-prop...)Show SMILES CC(C)[C@]1(Cc2cc(OCCCOc3cc(ccc3Cl)C(F)(F)F)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O5/c1-13(2)21(20(27)28)12-14-10-16(5-7-18(14)31-21)29-8-3-9-30-19-11-15(22(24,25)26)4-6-17(19)23/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H,27,28)/t21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171988
((S)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-2-20(19(26)27)12-13-10-14(4-6-17(13)31-20)28-8-3-9-29-18-7-5-15(11-16(18)22)30-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27)/t20-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172000
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-phenoxy]-...)Show SMILES OC(=O)C1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(F)(F)F Show InChI InChI=1S/C21H17ClF6O5/c22-15-8-12(10-20(23,24)25)2-4-17(15)32-7-1-6-31-14-3-5-16-13(9-14)11-19(33-16,18(29)30)21(26,27)28/h2-5,8-9H,1,6-7,10-11H2,(H,29,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172001
(5-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-propoxy]...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(cc3Cl)C(F)(F)F)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O5/c1-2-20(19(26)27)12-13-10-15(5-7-17(13)30-20)28-8-3-9-29-18-6-4-14(11-16(18)22)21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171987
(2-Benzyl-5-[3-(2-chloro-4-trifluoromethoxy-phenoxy...)Show SMILES OC(=O)C1(Cc2ccccc2)Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1 Show InChI InChI=1S/C26H22ClF3O6/c27-21-14-20(35-26(28,29)30)8-10-23(21)34-12-4-11-33-19-7-9-22-18(13-19)16-25(36-22,24(31)32)15-17-5-2-1-3-6-17/h1-3,5-10,13-14H,4,11-12,15-16H2,(H,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171992
((S)-5-{3-[2-Chloro-4-(3,3,3-trifluoro-propyl)-phen...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(CCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C23H24ClF3O5/c1-2-22(21(28)29)14-16-13-17(5-7-19(16)32-22)30-10-3-11-31-20-6-4-15(12-18(20)24)8-9-23(25,26)27/h4-7,12-13H,2-3,8-11,14H2,1H3,(H,28,29)/t22-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171986
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES OC(=O)C1Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1 Show InChI InChI=1S/C20H18ClF3O6/c21-15-10-14(29-11-20(22,23)24)3-5-17(15)28-7-1-6-27-13-2-4-16-12(8-13)9-18(30-16)19(25)26/h2-5,8,10,18H,1,6-7,9,11H2,(H,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50172003
((R)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC(C)[C@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-13(2)21(20(27)28)12-14-10-15(4-6-18(14)32-21)29-8-3-9-30-19-7-5-16(11-17(19)23)31-22(24,25)26/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H,27,28)/t21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171991
(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(cc3Cl)C(C)(C)C)ccc2O1)C(O)=O Show InChI InChI=1S/C24H29ClO5/c1-5-24(22(26)27)15-16-13-18(8-10-20(16)30-24)28-11-6-12-29-21-9-7-17(14-19(21)25)23(2,3)4/h7-10,13-14H,5-6,11-12,15H2,1-4H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171988
((S)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-2-20(19(26)27)12-13-10-14(4-6-17(13)31-20)28-8-3-9-29-18-7-5-15(11-16(18)22)30-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27)/t20-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50172005
((S)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC(C)[C@@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-13(2)21(20(27)28)12-14-10-15(4-6-18(14)32-21)29-8-3-9-30-19-7-5-16(11-17(19)23)31-22(24,25)26/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H,27,28)/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50172004
((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O5/c1-2-21(20(27)28)13-15-11-16(5-7-18(15)31-21)29-8-3-9-30-19-6-4-14(10-17(19)23)12-22(24,25)26/h4-7,10-11H,2-3,8-9,12-13H2,1H3,(H,27,28)/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171999
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES CC1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-20(19(26)27)11-13-9-14(3-5-17(13)31-20)28-7-2-8-29-18-6-4-15(10-16(18)22)30-12-21(23,24)25/h3-6,9-10H,2,7-8,11-12H2,1H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172003
((R)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC(C)[C@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-13(2)21(20(27)28)12-14-10-15(4-6-18(14)32-21)29-8-3-9-30-19-7-5-16(11-17(19)23)31-22(24,25)26/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H,27,28)/t21-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171990
((S)-2-Ethyl-5-{3-[4-(2,2,2-trifluoro-ethoxy)-pheno...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3)ccc2O1)C(O)=O Show InChI InChI=1S/C22H23F3O6/c1-2-21(20(26)27)13-15-12-18(8-9-19(15)31-21)29-11-3-10-28-16-4-6-17(7-5-16)30-14-22(23,24)25/h4-9,12H,2-3,10-11,13-14H2,1H3,(H,26,27)/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171992
((S)-5-{3-[2-Chloro-4-(3,3,3-trifluoro-propyl)-phen...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(CCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C23H24ClF3O5/c1-2-22(21(28)29)14-16-13-17(5-7-19(16)32-22)30-10-3-11-31-20-6-4-15(12-18(20)24)8-9-23(25,26)27/h4-7,12-13H,2-3,8-11,14H2,1H3,(H,28,29)/t22-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171989
((R)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC[C@@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-2-20(19(26)27)12-13-10-14(4-6-17(13)31-20)28-8-3-9-29-18-7-5-15(11-16(18)22)30-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27)/t20-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171986
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES OC(=O)C1Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1 Show InChI InChI=1S/C20H18ClF3O6/c21-15-10-14(29-11-20(22,23)24)3-5-17(15)28-7-1-6-27-13-2-4-16-12(8-13)9-18(30-16)19(25)26/h2-5,8,10,18H,1,6-7,9,11H2,(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171994
((R)-5-[3-(2-Chloro-5-trifluoromethyl-phenoxy)-prop...)Show SMILES CC(C)[C@]1(Cc2cc(OCCCOc3cc(ccc3Cl)C(F)(F)F)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O5/c1-13(2)21(20(27)28)12-14-10-16(5-7-18(14)31-21)29-8-3-9-30-19-11-15(22(24,25)26)4-6-17(19)23/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H,27,28)/t21-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172004
((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O5/c1-2-21(20(27)28)13-15-11-16(5-7-18(15)31-21)29-8-3-9-30-19-6-4-14(10-17(19)23)12-22(24,25)26/h4-7,10-11H,2-3,8-9,12-13H2,1H3,(H,27,28)/t21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171985
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-2-21(20(27)28)12-14-10-15(4-6-18(14)32-21)29-8-3-9-30-19-7-5-16(11-17(19)23)31-13-22(24,25)26/h4-7,10-11H,2-3,8-9,12-13H2,1H3,(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171985
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-2-21(20(27)28)12-14-10-15(4-6-18(14)32-21)29-8-3-9-30-19-7-5-16(11-17(19)23)31-13-22(24,25)26/h4-7,10-11H,2-3,8-9,12-13H2,1H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172006
(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)Show SMILES CC(C)(C)C1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C24H26ClF3O5/c1-22(2,3)23(21(29)30)14-16-12-17(6-8-19(16)33-23)31-9-4-10-32-20-7-5-15(11-18(20)25)13-24(26,27)28/h5-8,11-12H,4,9-10,13-14H2,1-3H3,(H,29,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171987
(2-Benzyl-5-[3-(2-chloro-4-trifluoromethoxy-phenoxy...)Show SMILES OC(=O)C1(Cc2ccccc2)Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1 Show InChI InChI=1S/C26H22ClF3O6/c27-21-14-20(35-26(28,29)30)8-10-23(21)34-12-4-11-33-19-7-9-22-18(13-19)16-25(36-22,24(31)32)15-17-5-2-1-3-6-17/h1-3,5-10,13-14H,4,11-12,15-16H2,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171995
((R)-5-[2-(2-Chloro-4-trifluoromethoxy-phenoxy)-eth...)Show SMILES CC(C)[C@]1(Cc2cc(OCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-12(2)20(19(26)27)11-13-9-14(3-5-17(13)31-20)28-7-8-29-18-6-4-15(10-16(18)22)30-21(23,24)25/h3-6,9-10,12H,7-8,11H2,1-2H3,(H,26,27)/t20-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171998
((R)-2-tert-Butyl-5-[2-(2-chloro-4-trifluoromethoxy...)Show SMILES CC(C)(C)[C@]1(Cc2cc(OCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-20(2,3)21(19(27)28)12-13-10-14(4-6-17(13)32-21)29-8-9-30-18-7-5-15(11-16(18)23)31-22(24,25)26/h4-7,10-11H,8-9,12H2,1-3H3,(H,27,28)/t21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171997
(5-{3-[2-Chloro-4-(2,2-dimethyl-propyl)-phenoxy]-pr...)Show SMILES CCC1(Cc2cc(OCCCOc3ccc(CC(C)(C)C)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C25H31ClO5/c1-5-25(23(27)28)16-18-14-19(8-10-21(18)31-25)29-11-6-12-30-22-9-7-17(13-20(22)26)15-24(2,3)4/h7-10,13-14H,5-6,11-12,15-16H2,1-4H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172005
((S)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC(C)[C@@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-13(2)21(20(27)28)12-14-10-15(4-6-18(14)32-21)29-8-3-9-30-19-7-5-16(11-17(19)23)31-22(24,25)26/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H,27,28)/t21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171998
((R)-2-tert-Butyl-5-[2-(2-chloro-4-trifluoromethoxy...)Show SMILES CC(C)(C)[C@]1(Cc2cc(OCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O6/c1-20(2,3)21(19(27)28)12-13-10-14(4-6-17(13)32-21)29-8-9-30-18-7-5-15(11-16(18)23)31-22(24,25)26/h4-7,10-11H,8-9,12H2,1-3H3,(H,27,28)/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171989
((R)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)Show SMILES CC[C@@]1(Cc2cc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-2-20(19(26)27)12-13-10-14(4-6-17(13)31-20)28-8-3-9-29-18-7-5-15(11-16(18)22)30-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27)/t20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50172006
(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)Show SMILES CC(C)(C)C1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C24H26ClF3O5/c1-22(2,3)23(21(29)30)14-16-12-17(6-8-19(16)33-23)31-9-4-10-32-20-7-5-15(11-18(20)25)13-24(26,27)28/h5-8,11-12H,4,9-10,13-14H2,1-3H3,(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50171995
((R)-5-[2-(2-Chloro-4-trifluoromethoxy-phenoxy)-eth...)Show SMILES CC(C)[C@]1(Cc2cc(OCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-12(2)20(19(26)27)11-13-9-14(3-5-17(13)31-20)28-7-8-29-18-6-4-15(10-16(18)22)30-21(23,24)25/h3-6,9-10,12H,7-8,11H2,1-2H3,(H,26,27)/t20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-delta |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171990
((S)-2-Ethyl-5-{3-[4-(2,2,2-trifluoro-ethoxy)-pheno...)Show SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3)ccc2O1)C(O)=O Show InChI InChI=1S/C22H23F3O6/c1-2-21(20(26)27)13-15-12-18(8-9-19(15)31-21)29-11-3-10-28-16-4-6-17(7-5-16)30-14-22(23,24)25/h4-9,12H,2-3,10-11,13-14H2,1H3,(H,26,27)/t21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity for PPAR-gamma |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50171995
((R)-5-[2-(2-Chloro-4-trifluoromethoxy-phenoxy)-eth...)Show SMILES CC(C)[C@]1(Cc2cc(OCCOc3ccc(OC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-12(2)20(19(26)27)11-13-9-14(3-5-17(13)31-20)28-7-8-29-18-6-4-15(10-16(18)22)30-21(23,24)25/h3-6,9-10,12H,7-8,11H2,1-2H3,(H,26,27)/t20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Canis familiaris) | BDBM50171986
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES OC(=O)C1Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1 Show InChI InChI=1S/C20H18ClF3O6/c21-15-10-14(29-11-20(22,23)24)3-5-17(15)28-7-1-6-27-13-2-4-16-12(8-13)9-18(30-16)19(25)26/h2-5,8,10,18H,1,6-7,9,11H2,(H,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Effective concentration against canine PPAR-alpha in Gal4 transactivation assay |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50171999
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES CC1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-20(19(26)27)11-13-9-14(3-5-17(13)31-20)28-7-2-8-29-18-6-4-15(10-16(18)22)30-12-21(23,24)25/h3-6,9-10H,2,7-8,11-12H2,1H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 138 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Canis familiaris) | BDBM50172002
(6-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy...)Show SMILES CCC1(Cc2ccc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)cc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-2-20(19(26)27)12-13-4-5-14(11-18(13)31-20)28-8-3-9-29-17-7-6-15(10-16(17)22)30-21(23,24)25/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | <1 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50171994
((R)-5-[3-(2-Chloro-5-trifluoromethyl-phenoxy)-prop...)Show SMILES CC(C)[C@]1(Cc2cc(OCCCOc3cc(ccc3Cl)C(F)(F)F)ccc2O1)C(O)=O Show InChI InChI=1S/C22H22ClF3O5/c1-13(2)21(20(27)28)12-14-10-16(5-7-18(14)31-21)29-8-3-9-30-19-11-15(22(24,25)26)4-6-17(19)23/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H,27,28)/t21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 420 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50171999
(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)Show SMILES CC1(Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1)C(O)=O Show InChI InChI=1S/C21H20ClF3O6/c1-20(19(26)27)11-13-9-14(3-5-17(13)31-20)28-7-2-8-29-18-6-4-15(10-16(18)22)30-12-21(23,24)25/h3-6,9-10H,2,7-8,11-12H2,1H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Factor Xa |
J Med Chem 48: 5589-99 (2005)
Article DOI: 10.1021/jm050373g BindingDB Entry DOI: 10.7270/Q25T3K0M |
More data for this Ligand-Target Pair | |