Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-P receptor (Homo sapiens (Human)) | BDBM50287337 (CHEMBL291025 | N-[2-(3,5-Bis-trifluoromethyl-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287354 (CHEMBL291074 | N-[2-(3,5-Bis-trifluoromethyl-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287355 (CHEMBL288382 | N-(3,5-Dichloro-benzyl)-N-methyl-3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287345 (CHEMBL43085 | N-[2-(3,5-Bis-trifluoromethyl-phenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287349 (CHEMBL39089 | N-(3,5-Bis-trifluoromethyl-benzyl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287340 (CHEMBL40817 | N-(3,5-Bis-trifluoromethyl-benzyl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287358 (CHEMBL288340 | N-[2-(3,5-Bis-trifluoromethyl-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287341 (2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287351 (CHEMBL41124 | N-(3,5-Bis-trifluoromethyl-phenyl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287352 (CHEMBL417519 | N-(3,5-Dimethoxy-benzyl)-N-methyl-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 226 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287347 (CHEMBL436698 | N-(3,5-Dichloro-benzyl)-3,3-dipheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 226 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287348 (CHEMBL289728 | N-(3,5-Bis-trifluoromethyl-benzyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 235 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287357 (CHEMBL42972 | N-(2,2-Diphenyl-ethyl)-N-methyl-3,5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 297 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287356 (CHEMBL40262 | N-(3,5-Bis-trifluoromethyl-phenyl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287350 (CHEMBL41705 | N-[3-(3,5-Bis-trifluoromethyl-phenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 304 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287335 (CHEMBL40620 | N-[3-(3,5-Bis-trifluoromethyl-phenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 323 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287343 (2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 378 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287336 (CHEMBL43027 | N-(3,5-Bis-trifluoromethyl-benzyl)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 526 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287342 (CHEMBL417881 | N-[3-(3,5-Bis-trifluoromethyl-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 593 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287353 (CHEMBL417522 | N-[3-(3,5-Bis-trifluoromethyl-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287338 (CHEMBL40164 | N-(3,5-Dimethoxy-benzyl)-3,3-dipheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287339 (CHEMBL40969 | N-(3,5-Bis-trifluoromethyl-phenyl)-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287344 (CHEMBL40587 | N-(2,2-Diphenyl-ethyl)-3,5-bis-trifl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Substance-P receptor (Homo sapiens (Human)) | BDBM50287346 (CHEMBL41762 | N-(3,5-Bis-trifluoromethyl-phenyl)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells | Bioorg Med Chem Lett 6: 1585-1588 (1996) Article DOI: 10.1016/S0960-894X(96)00280-6 BindingDB Entry DOI: 10.7270/Q24X57RT | |||||||||||
More data for this Ligand-Target Pair |