Compile Data Set for Download or QSAR

Found 230 hits Enz. Inhib. hit(s) with all data for entry = 50030031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50175491 (4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...) Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C24H21N5O/c1-16-5-8-18(9-6-16)23(30)27-20-10-7-17(2)22(14-20)29-24-26-13-11-21(28-24)19-4-3-12-25-15-19/h3-15H,1-2H3,(H,27,30)(H,26,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50287090 (4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...) Show SMILES Cc1ccc(NC(=O)c2ccc(Cl)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C23H18ClN5O/c1-15-4-9-19(27-22(30)16-5-7-18(24)8-6-16)13-21(15)29-23-26-12-10-20(28-23)17-3-2-11-25-14-17/h2-14H,1H3,(H,27,30)(H,26,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50287091 (CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...) Show SMILES Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C27H21N5O/c1-18-8-11-23(30-26(33)21-10-9-19-5-2-3-6-20(19)15-21)16-25(18)32-27-29-14-12-24(31-27)22-7-4-13-28-17-22/h2-17H,1H3,(H,30,33)(H,29,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50240407 (CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...) Show SMILES Cc1ccc(NC(=O)c2ccccc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C23H19N5O/c1-16-9-10-19(26-22(29)17-6-3-2-4-7-17)14-21(16)28-23-25-13-11-20(27-23)18-8-5-12-24-15-18/h2-15H,1H3,(H,26,29)(H,25,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cccc(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C28H29N7O/c1-34-14-16-35(17-15-34)20-21-7-9-22(10-8-21)27(36)31-24-5-2-6-25(18-24)32-28-30-13-11-26(33-28)23-4-3-12-29-19-23/h2-13,18-19H,14-17,20H2,1H3,(H,31,36)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290417 (2-Amino-pyrimidine, 19 | CHEMBL418270 | N-[3-(4-Py...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1cccnc1 Show InChI InChI=1S/C21H16N6O/c28-20(16-5-3-10-23-14-16)25-17-6-1-7-18(12-17)26-21-24-11-8-19(27-21)15-4-2-9-22-13-15/h1-14H,(H,25,28)(H,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290416 (CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...) Show SMILES NCCCn1ccc2c(cccc12)-c1ccnc(Nc2cccc(OC(F)(F)C(F)F)c2)n1 Show InChI InChI=1S/C23H21F4N5O/c24-21(25)23(26,27)33-16-5-1-4-15(14-16)30-22-29-11-8-19(31-22)17-6-2-7-20-18(17)9-13-32(20)12-3-10-28/h1-2,4-9,11,13-14,21H,3,10,12,28H2,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290431 (CHEMBL56669 | Hexanoic acid [3-(4-pyridin-3-yl-pyr...) Show SMILES CCCCCC(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C21H23N5O/c1-2-3-4-10-20(27)24-17-8-5-9-18(14-17)25-21-23-13-11-19(26-21)16-7-6-12-22-15-16/h5-9,11-15H,2-4,10H2,1H3,(H,24,27)(H,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290412 (4-Fluoro-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Fc1ccc(cc1)C(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C22H16FN5O/c23-17-8-6-15(7-9-17)21(29)26-18-4-1-5-19(13-18)27-22-25-12-10-20(28-22)16-3-2-11-24-14-16/h1-14H,(H,26,29)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50287091 (CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...) Show SMILES Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C27H21N5O/c1-18-8-11-23(30-26(33)21-10-9-19-5-2-3-6-20(19)15-21)16-25(18)32-27-29-14-12-24(31-27)22-7-4-13-28-17-22/h2-17H,1H3,(H,30,33)(H,29,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50175491 (4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...) Show SMILES Cc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C24H21N5O/c1-16-5-8-18(9-6-16)23(30)27-20-10-7-17(2)22(14-20)29-24-26-13-11-21(28-24)19-4-3-12-25-15-19/h3-15H,1-2H3,(H,27,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50290422 (4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cccc(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C28H29N7O/c1-34-14-16-35(17-15-34)20-21-7-9-22(10-8-21)27(36)31-24-5-2-6-25(18-24)32-28-30-13-11-26(33-28)23-4-3-12-29-19-23/h2-13,18-19H,14-17,20H2,1H3,(H,31,36)(H,30,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290413 (CHEMBL55379 | [4-(1H-Indol-3-yl)-pyrimidin-2-yl]-[...) Show SMILES FC(F)C(F)(F)Oc1cccc(Nc2nccc(n2)-c2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C20H14F4N4O/c21-18(22)20(23,24)29-13-5-3-4-12(10-13)27-19-25-9-8-17(28-19)15-11-26-16-7-2-1-6-14(15)16/h1-11,18,26H,(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50287096 (2-Methoxy-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-...) Show SMILES COc1ccccc1C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C24H21N5O2/c1-16-9-10-18(27-23(30)19-7-3-4-8-22(19)31-2)14-21(16)29-24-26-13-11-20(28-24)17-6-5-12-25-15-17/h3-15H,1-2H3,(H,27,30)(H,26,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290427 (CHEMBL56359 | Thiophene-2-carboxylic acid [3-(4-py...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1cccs1 Show InChI InChI=1S/C20H15N5OS/c26-19(18-7-3-11-27-18)23-15-5-1-6-16(12-15)24-20-22-10-8-17(25-20)14-4-2-9-21-13-14/h1-13H,(H,23,26)(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290420 ((4-Pyridin-4-yl-pyrimidin-2-yl)-[3-(1,1,2,2-tetraf...) Show SMILES FC(F)C(F)(F)Oc1cccc(Nc2nccc(n2)-c2ccncc2)c1 Show InChI InChI=1S/C17H12F4N4O/c18-15(19)17(20,21)26-13-3-1-2-12(10-13)24-16-23-9-6-14(25-16)11-4-7-22-8-5-11/h1-10,15H,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290429 (2-Methoxy-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino...) Show SMILES COc1ccccc1C(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C23H19N5O2/c1-30-21-10-3-2-9-19(21)22(29)26-17-7-4-8-18(14-17)27-23-25-13-11-20(28-23)16-6-5-12-24-15-16/h2-15H,1H3,(H,26,29)(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290411 (4-Cyano-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C23H16N6O/c24-14-16-6-8-17(9-7-16)22(30)27-19-4-1-5-20(13-19)28-23-26-12-10-21(29-23)18-3-2-11-25-15-18/h1-13,15H,(H,27,30)(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290416 (CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...) Show SMILES NCCCn1ccc2c(cccc12)-c1ccnc(Nc2cccc(OC(F)(F)C(F)F)c2)n1 Show InChI InChI=1S/C23H21F4N5O/c24-21(25)23(26,27)33-16-5-1-4-15(14-16)30-22-29-11-8-19(31-22)17-6-2-7-20-18(17)9-13-32(20)12-3-10-28/h1-2,4-9,11,13-14,21H,3,10,12,28H2,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290413 (CHEMBL55379 | [4-(1H-Indol-3-yl)-pyrimidin-2-yl]-[...) Show SMILES FC(F)C(F)(F)Oc1cccc(Nc2nccc(n2)-c2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C20H14F4N4O/c21-18(22)20(23,24)29-13-5-3-4-12(10-13)27-19-25-9-8-17(28-19)15-11-26-16-7-2-1-6-14(15)16/h1-11,18,26H,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290415 (CHEMBL59099 | N-(3-Amino-propyl)-3-(4-pyridin-3-yl...) Show SMILES NCCCNC(=O)c1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C19H20N6O/c20-8-3-10-22-18(26)14-4-1-6-16(12-14)24-19-23-11-7-17(25-19)15-5-2-9-21-13-15/h1-2,4-7,9,11-13H,3,8,10,20H2,(H,22,26)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50240407 (CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...) Show SMILES Cc1ccc(NC(=O)c2ccccc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C23H19N5O/c1-16-9-10-19(26-22(29)17-6-3-2-4-7-17)14-21(16)28-23-25-13-11-20(27-23)18-8-5-12-24-15-18/h2-15H,1H3,(H,26,29)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50175493 (CHEMBL277931 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yl...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccccc1 Show InChI InChI=1S/C22H17N5O/c28-21(16-6-2-1-3-7-16)25-18-9-4-10-19(14-18)26-22-24-13-11-20(27-22)17-8-5-12-23-15-17/h1-15H,(H,25,28)(H,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290419 (CHEMBL58142 | Cyclohexanecarboxylic acid [3-(4-pyr...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)C1CCCCC1 Show InChI InChI=1S/C22H23N5O/c28-21(16-6-2-1-3-7-16)25-18-9-4-10-19(14-18)26-22-24-13-11-20(27-22)17-8-5-12-23-15-17/h4-5,8-16H,1-3,6-7H2,(H,25,28)(H,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50290416 (CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...) Show SMILES NCCCn1ccc2c(cccc12)-c1ccnc(Nc2cccc(OC(F)(F)C(F)F)c2)n1 Show InChI InChI=1S/C23H21F4N5O/c24-21(25)23(26,27)33-16-5-1-4-15(14-16)30-22-29-11-8-19(31-22)17-6-2-7-20-18(17)9-13-32(20)12-3-10-28/h1-2,4-9,11,13-14,21H,3,10,12,28H2,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of c-Src-tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290421 (CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccncc1 Show InChI InChI=1S/C21H16N6O/c28-20(15-6-10-22-11-7-15)25-17-4-1-5-18(13-17)26-21-24-12-8-19(27-21)16-3-2-9-23-14-16/h1-14H,(H,25,28)(H,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50290416 (CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...) Show SMILES NCCCn1ccc2c(cccc12)-c1ccnc(Nc2cccc(OC(F)(F)C(F)F)c2)n1 Show InChI InChI=1S/C23H21F4N5O/c24-21(25)23(26,27)33-16-5-1-4-15(14-16)30-22-29-11-8-19(31-22)17-6-2-7-20-18(17)9-13-32(20)12-3-10-28/h1-2,4-9,11,13-14,21H,3,10,12,28H2,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the epidermal growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50045408 (CHEMBL57443 | N-(4-Pyridin-4-yl-pyrimidin-2-yl)-be...) Show SMILES Nc1cccc(Nc2nccc(n2)-c2ccncc2)c1 Show InChI InChI=1S/C15H13N5/c16-12-2-1-3-13(10-12)19-15-18-9-6-14(20-15)11-4-7-17-8-5-11/h1-10H,16H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50290431 (CHEMBL56669 | Hexanoic acid [3-(4-pyridin-3-yl-pyr...) Show SMILES CCCCCC(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C21H23N5O/c1-2-3-4-10-20(27)24-17-8-5-9-18(14-17)25-21-23-13-11-19(26-21)16-7-6-12-22-15-16/h5-9,11-15H,2-4,10H2,1H3,(H,24,27)(H,23,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50045528 (CHEMBL57553 | N-(4-Pyridin-3-yl-pyrimidin-2-yl)-be...) Show SMILES Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C15H13N5/c16-12-4-1-5-13(9-12)19-15-18-8-6-14(20-15)11-3-2-7-17-10-11/h1-10H,16H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290423 ((3-Nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-a...) Show SMILES [O-][N+](=O)c1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C15H11N5O2/c21-20(22)13-5-1-4-12(9-13)18-15-17-8-6-14(19-15)11-3-2-7-16-10-11/h1-10H,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50290419 (CHEMBL58142 | Cyclohexanecarboxylic acid [3-(4-pyr...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)C1CCCCC1 Show InChI InChI=1S/C22H23N5O/c28-21(16-6-2-1-3-7-16)25-18-9-4-10-19(14-18)26-22-24-13-11-20(27-22)17-8-5-12-23-15-17/h4-5,8-16H,1-3,6-7H2,(H,25,28)(H,24,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50287090 (4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...) Show SMILES Cc1ccc(NC(=O)c2ccc(Cl)cc2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C23H18ClN5O/c1-15-4-9-19(27-22(30)16-5-7-18(24)8-6-16)13-21(15)29-23-26-12-10-20(28-23)17-3-2-11-25-14-17/h2-14H,1H3,(H,27,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50290430 (4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Cc1ccc(cc1)C(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C23H19N5O/c1-16-7-9-17(10-8-16)22(29)26-19-5-2-6-20(14-19)27-23-25-13-11-21(28-23)18-4-3-12-24-15-18/h2-15H,1H3,(H,26,29)(H,25,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50287096 (2-Methoxy-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-...) Show SMILES COc1ccccc1C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C24H21N5O2/c1-16-9-10-18(27-23(30)19-7-3-4-8-22(19)31-2)14-21(16)29-24-26-13-11-20(28-24)17-6-5-12-25-15-17/h3-15H,1-2H3,(H,27,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290425 (CHEMBL57581 | [4-(4-Chloro-phenyl)-pyrimidin-2-yl]...) Show SMILES FC(F)C(F)(F)Oc1cccc(Nc2nccc(n2)-c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C18H12ClF4N3O/c19-12-6-4-11(5-7-12)15-8-9-24-17(26-15)25-13-2-1-3-14(10-13)27-18(22,23)16(20)21/h1-10,16H,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50045481 ((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...) Show SMILES N(c1cccc(c1)-n1ccnc1)c1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C18H14N6/c1-4-15(11-16(5-1)24-10-9-20-13-24)22-18-21-8-6-17(23-18)14-3-2-7-19-12-14/h1-13H,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50290429 (2-Methoxy-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino...) Show SMILES COc1ccccc1C(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C23H19N5O2/c1-30-21-10-3-2-9-19(21)22(29)26-17-7-4-8-18(14-17)27-23-25-13-11-20(28-23)16-6-5-12-24-15-16/h2-15H,1H3,(H,26,29)(H,25,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290430 (4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Cc1ccc(cc1)C(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C23H19N5O/c1-16-7-9-17(10-8-16)22(29)26-19-5-2-6-20(14-19)27-23-25-13-11-21(28-23)18-4-3-12-24-15-18/h2-15H,1H3,(H,26,29)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50045526 (CHEMBL58436 | [3-(2-Imidazol-1-yl-ethoxy)-phenyl]-...) Show SMILES C(Cn1ccnc1)Oc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C20H18N6O/c1-4-17(13-18(5-1)27-12-11-26-10-9-22-15-26)24-20-23-8-6-19(25-20)16-3-2-7-21-14-16/h1-10,13-15H,11-12H2,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50175493 (CHEMBL277931 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yl...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccccc1 Show InChI InChI=1S/C22H17N5O/c28-21(16-6-2-1-3-7-16)25-18-9-4-10-19(14-18)26-22-24-13-11-20(27-22)17-8-5-12-23-15-17/h1-15H,(H,25,28)(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290424 ((3-Nitro-phenyl)-(4-pyridin-2-yl-pyrimidin-2-yl)-a...) Show SMILES [O-][N+](=O)c1cccc(Nc2nccc(n2)-c2ccccn2)c1 Show InChI InChI=1S/C15H11N5O2/c21-20(22)12-5-3-4-11(10-12)18-15-17-9-7-14(19-15)13-6-1-2-8-16-13/h1-10H,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50290421 (CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccncc1 Show InChI InChI=1S/C21H16N6O/c28-20(15-6-10-22-11-7-15)25-17-4-1-5-18(13-17)26-21-24-12-8-19(27-21)16-3-2-9-23-14-16/h1-14H,(H,25,28)(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50290411 (4-Cyano-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C23H16N6O/c24-14-16-6-8-17(9-7-16)22(30)27-19-4-1-5-20(13-19)28-23-26-12-10-21(29-23)18-3-2-11-25-15-18/h1-13,15H,(H,27,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50290413 (CHEMBL55379 | [4-(1H-Indol-3-yl)-pyrimidin-2-yl]-[...) Show SMILES FC(F)C(F)(F)Oc1cccc(Nc2nccc(n2)-c2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C20H14F4N4O/c21-18(22)20(23,24)29-13-5-3-4-12(10-13)27-19-25-9-8-17(28-19)15-11-26-16-7-2-1-6-14(15)16/h1-11,18,26H,(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C delta.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50287097 (4-Methyl-N*3*-(4-pyridin-3-yl-pyrimidin-2-yl)-benz...) Show SMILES Cc1ccc(N)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C16H15N5/c1-11-4-5-13(17)9-15(11)21-16-19-8-6-14(20-16)12-3-2-7-18-10-12/h2-10H,17H2,1H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50045526 (CHEMBL58436 | [3-(2-Imidazol-1-yl-ethoxy)-phenyl]-...) Show SMILES C(Cn1ccnc1)Oc1cccc(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C20H18N6O/c1-4-17(13-18(5-1)27-12-11-26-10-9-22-15-26)24-20-23-8-6-19(25-20)16-3-2-7-21-14-16/h1-10,13-15H,11-12H2,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of protein kinase C alpha.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50290411 (4-Cyano-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-...) Show SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C23H16N6O/c24-14-16-6-8-17(9-7-16)22(30)27-19-4-1-5-20(13-19)28-23-26-12-10-21(29-23)18-3-2-11-25-15-18/h1-13,15H,(H,27,30)(H,26,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the platelet-derived growth factor receptor.				Bioorg Med Chem Lett 7: 187-192 (1997) Article DOI: 10.1016/S0960-894X(96)00601-4 BindingDB Entry DOI: 10.7270/Q23X86MF
					More data for this Ligand-Target Pair

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