Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosylhomocysteinase (Rattus norvegicus) | BDBM50316222 (CHEMBL1095280 | D-ERITADENINE | eritadenine) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College Curated by ChEMBL | Assay Description Inhibition of S-adenosyl-L-homocysteine hydrolase in intact rat hepatocytes | Bioorg Med Chem 17: 6707-14 (2009) Article DOI: 10.1016/j.bmc.2009.07.061 BindingDB Entry DOI: 10.7270/Q2JD4X0D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50316223 (3-(6-Amino-purin-9-ylmethyl)-5-cyclohexylmethoxy-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College Curated by ChEMBL | Assay Description Inhibition of S-adenosyl-L-homocysteine hydrolase after 10 mins by scintillation counting | Bioorg Med Chem 17: 6707-14 (2009) Article DOI: 10.1016/j.bmc.2009.07.061 BindingDB Entry DOI: 10.7270/Q2JD4X0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50006222 ((1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-hydroxymethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College Curated by ChEMBL | Assay Description Inhibition of S-adenosyl-L-homocysteine hydrolase | Bioorg Med Chem 17: 6707-14 (2009) Article DOI: 10.1016/j.bmc.2009.07.061 BindingDB Entry DOI: 10.7270/Q2JD4X0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50240866 ((-)-ilimaquinone | 2-Hydroxy-5-methoxy-3-((1R,2S,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College Curated by ChEMBL | Assay Description Inhibition of S-adenosyl-L-homocysteine hydrolase after 10 mins by scintillation counting | Bioorg Med Chem 17: 6707-14 (2009) Article DOI: 10.1016/j.bmc.2009.07.061 BindingDB Entry DOI: 10.7270/Q2JD4X0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50316224 ((2R,4aS,5R,6S,8aS)-5-((2-chloro-5-methoxy-3,6-diox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston College Curated by ChEMBL | Assay Description Inhibition of S-adenosyl-L-homocysteine hydrolase after 10 mins by scintillation counting | Bioorg Med Chem 17: 6707-14 (2009) Article DOI: 10.1016/j.bmc.2009.07.061 BindingDB Entry DOI: 10.7270/Q2JD4X0D | |||||||||||
More data for this Ligand-Target Pair |