Found 83 hits Enz. Inhib. hit(s) with all data for entry = 50032484 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329985
(2-(3'-chlorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H15ClN2O2S/c1-26(24,25)17-9-10-18-19(12-17)23-20(22-18)14-7-5-13(6-8-14)15-3-2-4-16(21)11-15/h2-12H,1H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329991
(2-(6-(2-fluorophenyl)pyridin-3-yl)-6-(methylsulfon...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(nc1)-c1ccccc1F Show InChI InChI=1S/C19H14FN3O2S/c1-26(24,25)13-7-9-17-18(10-13)23-19(22-17)12-6-8-16(21-11-12)14-4-2-3-5-15(14)20/h2-11H,1H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329984
(2-(biphenyl-4-yl)-6-(methylsulfonyl)-1H-benzo[d]im...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-25(23,24)17-11-12-18-19(13-17)22-20(21-18)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-13H,1H3,(H,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329972
(2-(3'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(F)c1 Show InChI InChI=1S/C20H15FN2O2S/c1-26(24,25)17-9-10-18-19(12-17)23-20(22-18)14-7-5-13(6-8-14)15-3-2-4-16(21)11-15/h2-12H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329984
(2-(biphenyl-4-yl)-6-(methylsulfonyl)-1H-benzo[d]im...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-25(23,24)17-11-12-18-19(13-17)22-20(21-18)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-13H,1H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329994
(2-(4'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H15FN2O2S/c1-26(24,25)17-10-11-18-19(12-17)23-20(22-18)15-4-2-13(3-5-15)14-6-8-16(21)9-7-14/h2-12H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329966
(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C20H15FN2O2S/c1-26(24,25)15-10-11-18-19(12-15)23-20(22-18)14-8-6-13(7-9-14)16-4-2-3-5-17(16)21/h2-12H,1H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329972
(2-(3'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(F)c1 Show InChI InChI=1S/C20H15FN2O2S/c1-26(24,25)17-9-10-18-19(12-17)23-20(22-18)14-7-5-13(6-8-14)15-3-2-4-16(21)11-15/h2-12H,1H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329988
(2-(biphenyl-4-yl)-7-(methylsulfonyl)imidazo[1,2-a]...)Show SMILES CS(=O)(=O)c1ccn2cc(nc2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-25(23,24)18-11-12-22-14-19(21-20(22)13-18)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-14H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329991
(2-(6-(2-fluorophenyl)pyridin-3-yl)-6-(methylsulfon...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(nc1)-c1ccccc1F Show InChI InChI=1S/C19H14FN3O2S/c1-26(24,25)13-7-9-17-18(10-13)23-19(22-17)12-6-8-16(21-11-12)14-4-2-3-5-15(14)20/h2-11H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329988
(2-(biphenyl-4-yl)-7-(methylsulfonyl)imidazo[1,2-a]...)Show SMILES CS(=O)(=O)c1ccn2cc(nc2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-25(23,24)18-11-12-22-14-19(21-20(22)13-18)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-14H,1H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329966
(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C20H15FN2O2S/c1-26(24,25)15-10-11-18-19(12-15)23-20(22-18)14-8-6-13(7-9-14)16-4-2-3-5-17(16)21/h2-12H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329964
(2-(2'-fluorobiphenyl-4-yl)-1H-benzo[d]imidazole-6-...)Show SMILES NS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C19H14FN3O2S/c20-16-4-2-1-3-15(16)12-5-7-13(8-6-12)19-22-17-10-9-14(26(21,24)25)11-18(17)23-19/h1-11H,(H,22,23)(H2,21,24,25) | PDB
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329995
(2-(3'-chloro-2'-fluorobiphenyl-4-yl)-6-(methylsulf...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(Cl)c1F Show InChI InChI=1S/C20H14ClFN2O2S/c1-27(25,26)14-9-10-17-18(11-14)24-20(23-17)13-7-5-12(6-8-13)15-3-2-4-16(21)19(15)22/h2-11H,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329965
(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfinyl)-1H-b...)Show SMILES CS(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C20H15FN2OS/c1-25(24)15-10-11-18-19(12-15)23-20(22-18)14-8-6-13(7-9-14)16-4-2-3-5-17(16)21/h2-12H,1H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329978
(6-(methylsulfonyl)-2-(4-(thiophen-2-yl)phenyl)-1H-...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C18H14N2O2S2/c1-24(21,22)14-8-9-15-16(11-14)20-18(19-15)13-6-4-12(5-7-13)17-3-2-10-23-17/h2-11H,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329996
(6-(methylsulfonyl)-2-(4-(thiophen-3-yl)phenyl)-1H-...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C18H14N2O2S2/c1-24(21,22)15-6-7-16-17(10-15)20-18(19-16)13-4-2-12(3-5-13)14-8-9-23-11-14/h2-11H,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329979
(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-i...)Show SMILES CS(=O)(=O)c1cnc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C19H14FN3O2S/c1-26(24,25)14-10-17-19(21-11-14)23-18(22-17)13-8-6-12(7-9-13)15-4-2-3-5-16(15)20/h2-11H,1H3,(H,21,22,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329985
(2-(3'-chlorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H15ClN2O2S/c1-26(24,25)17-9-10-18-19(12-17)23-20(22-18)14-7-5-13(6-8-14)15-3-2-4-16(21)11-15/h2-12H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329979
(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-i...)Show SMILES CS(=O)(=O)c1cnc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C19H14FN3O2S/c1-26(24,25)14-10-17-19(21-11-14)23-18(22-17)13-8-6-12(7-9-13)15-4-2-3-5-16(15)20/h2-11H,1H3,(H,21,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 156 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329986
(6-tert-butyl-2-(2'-fluorobiphenyl-4-yl)-1H-benzo[d...)Show SMILES CC(C)(C)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C23H21FN2/c1-23(2,3)17-12-13-20-21(14-17)26-22(25-20)16-10-8-15(9-11-16)18-6-4-5-7-19(18)24/h4-14H,1-3H3,(H,25,26) | PDB
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PubMed
| n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329992
(2-(5-(2-fluorophenyl)pyridin-2-yl)-6-(methylsulfon...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cn1)-c1ccccc1F Show InChI InChI=1S/C19H14FN3O2S/c1-26(24,25)13-7-9-16-18(10-13)23-19(22-16)17-8-6-12(11-21-17)14-4-2-3-5-15(14)20/h2-11H,1H3,(H,22,23) | PDB
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PubMed
| n/a | n/a | 227 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329978
(6-(methylsulfonyl)-2-(4-(thiophen-2-yl)phenyl)-1H-...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C18H14N2O2S2/c1-24(21,22)14-8-9-15-16(11-14)20-18(19-15)13-6-4-12(5-7-13)17-3-2-10-23-17/h2-11H,1H3,(H,19,20) | PDB
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| n/a | n/a | 231 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329973
(2-(2'-chlorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1Cl Show InChI InChI=1S/C20H15ClN2O2S/c1-26(24,25)15-10-11-18-19(12-15)23-20(22-18)14-8-6-13(7-9-14)16-4-2-3-5-17(16)21/h2-12H,1H3,(H,22,23) | PDB
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PubMed
| n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329997
(2-(5'-chloro-2'-fluorobiphenyl-4-yl)-6-(methylsulf...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cc(Cl)ccc1F Show InChI InChI=1S/C20H14ClFN2O2S/c1-27(25,26)15-7-9-18-19(11-15)24-20(23-18)13-4-2-12(3-5-13)16-10-14(21)6-8-17(16)22/h2-11H,1H3,(H,23,24) | PDB
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PubMed
| n/a | n/a | 278 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329970
(4'-(6-(methylsulfonyl)-1H-benzo[d]imidazol-2-yl)bi...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccc(O)cc1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)17-10-11-18-19(12-17)22-20(21-18)15-4-2-13(3-5-15)14-6-8-16(23)9-7-14/h2-12,23H,1H3,(H,21,22) | PDB
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PubMed
| n/a | n/a | 304 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329998
(2-(3'-methylbiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES Cc1cccc(c1)-c1ccc(cc1)-c1nc2ccc(cc2[nH]1)S(C)(=O)=O Show InChI InChI=1S/C21H18N2O2S/c1-14-4-3-5-17(12-14)15-6-8-16(9-7-15)21-22-19-11-10-18(26(2,24)25)13-20(19)23-21/h3-13H,1-2H3,(H,22,23) | PDB
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PubMed
| n/a | n/a | 319 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329999
(4'-(6-(methylsulfonyl)-1H-benzo[d]imidazol-2-yl)bi...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1O Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)15-10-11-17-18(12-15)22-20(21-17)14-8-6-13(7-9-14)16-4-2-3-5-19(16)23/h2-12,23H,1H3,(H,21,22) | PDB
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| n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329971
(4'-(6-(methylsulfonyl)-1H-benzo[d]imidazol-2-yl)bi...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(O)c1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)17-9-10-18-19(12-17)22-20(21-18)14-7-5-13(6-8-14)15-3-2-4-16(23)11-15/h2-12,23H,1H3,(H,21,22) | PDB
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| n/a | n/a | 342 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329964
(2-(2'-fluorobiphenyl-4-yl)-1H-benzo[d]imidazole-6-...)Show SMILES NS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C19H14FN3O2S/c20-16-4-2-1-3-15(16)12-5-7-13(8-6-12)19-22-17-10-9-14(26(21,24)25)11-18(17)23-19/h1-11H,(H,22,23)(H2,21,24,25) | PDB
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| n/a | n/a | 343 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329977
(2-(4-(furan-3-yl)phenyl)-6-(methylsulfonyl)-1H-ben...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccoc1 Show InChI InChI=1S/C18H14N2O3S/c1-24(21,22)15-6-7-16-17(10-15)20-18(19-16)13-4-2-12(3-5-13)14-8-9-23-11-14/h2-11H,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 395 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329971
(4'-(6-(methylsulfonyl)-1H-benzo[d]imidazol-2-yl)bi...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(O)c1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)17-9-10-18-19(12-17)22-20(21-18)14-7-5-13(6-8-14)15-3-2-4-16(23)11-15/h2-12,23H,1H3,(H,21,22) | PDB
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PubMed
| n/a | n/a | 396 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50330000
(6-(cyclopropylsulfonyl)-2-(2'-fluorobiphenyl-4-yl)...)Show SMILES Fc1ccccc1-c1ccc(cc1)-c1nc2ccc(cc2[nH]1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C22H17FN2O2S/c23-19-4-2-1-3-18(19)14-5-7-15(8-6-14)22-24-20-12-11-17(13-21(20)25-22)28(26,27)16-9-10-16/h1-8,11-13,16H,9-10H2,(H,24,25) | PDB
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| n/a | n/a | 401 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50330001
(6-(methylsulfonyl)-2-(4-(pyridin-3-yl)phenyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C19H15N3O2S/c1-25(23,24)16-8-9-17-18(11-16)22-19(21-17)14-6-4-13(5-7-14)15-3-2-10-20-12-15/h2-12H,1H3,(H,21,22) | PDB
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PubMed
| n/a | n/a | 425 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329965
(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfinyl)-1H-b...)Show SMILES CS(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C20H15FN2OS/c1-25(24)15-10-11-18-19(12-15)23-20(22-18)14-8-6-13(7-9-14)16-4-2-3-5-17(16)21/h2-12H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 472 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50330002
(6-(methylsulfonyl)-2-(4-(3-methylthiophen-2-yl)phe...)Show SMILES Cc1ccsc1-c1ccc(cc1)-c1nc2ccc(cc2[nH]1)S(C)(=O)=O Show InChI InChI=1S/C19H16N2O2S2/c1-12-9-10-24-18(12)13-3-5-14(6-4-13)19-20-16-8-7-15(25(2,22)23)11-17(16)21-19/h3-11H,1-2H3,(H,20,21) | PDB
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PubMed
| n/a | n/a | 472 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329990
(6-(methylsulfonyl)-2-(2-phenylpyrimidin-5-yl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1cnc(nc1)-c1ccccc1 Show InChI InChI=1S/C18H14N4O2S/c1-25(23,24)14-7-8-15-16(9-14)22-18(21-15)13-10-19-17(20-11-13)12-5-3-2-4-6-12/h2-11H,1H3,(H,21,22) | PDB
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 489 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50330003
(2-(2'-fluorobiphenyl-4-yl)-N,N-dimethyl-1H-benzo[d...)Show SMILES CN(C)S(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C21H18FN3O2S/c1-25(2)28(26,27)16-11-12-19-20(13-16)24-21(23-19)15-9-7-14(8-10-15)17-5-3-4-6-18(17)22/h3-13H,1-2H3,(H,23,24) | PDB
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PubMed
| n/a | n/a | 528 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50330004
(2-(2'-fluorobiphenyl-4-yl)-6-(methylthio)-1H-benzo...)Show InChI InChI=1S/C20H15FN2S/c1-24-15-10-11-18-19(12-15)23-20(22-18)14-8-6-13(7-9-14)16-4-2-3-5-17(16)21/h2-12H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | 697 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329986
(6-tert-butyl-2-(2'-fluorobiphenyl-4-yl)-1H-benzo[d...)Show SMILES CC(C)(C)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C23H21FN2/c1-23(2,3)17-12-13-20-21(14-17)26-22(25-20)16-10-8-15(9-11-16)18-6-4-5-7-19(18)24/h4-14H,1-3H3,(H,25,26) | PDB
KEGG
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antibodypedia
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PubMed
| n/a | n/a | 731 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329967
(6-(ethylsulfonyl)-2-(2'-fluorobiphenyl-4-yl)-1H-be...)Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C21H17FN2O2S/c1-2-27(25,26)16-11-12-19-20(13-16)24-21(23-19)15-9-7-14(8-10-15)17-5-3-4-6-18(17)22/h3-13H,2H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329967
(6-(ethylsulfonyl)-2-(2'-fluorobiphenyl-4-yl)-1H-be...)Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C21H17FN2O2S/c1-2-27(25,26)16-11-12-19-20(13-16)24-21(23-19)15-9-7-14(8-10-15)17-5-3-4-6-18(17)22/h3-13H,2H2,1H3,(H,23,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA (8-3)-desaturase
(Homo sapiens (Human)) | BDBM50329966
(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C20H15FN2O2S/c1-26(24,25)15-10-11-18-19(12-15)23-20(22-18)14-8-6-13(7-9-14)16-4-2-3-5-17(16)21/h2-12H,1H3,(H,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of Delta(5) fatty acid desaturase in human HepG2 cells |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329977
(2-(4-(furan-3-yl)phenyl)-6-(methylsulfonyl)-1H-ben...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccoc1 Show InChI InChI=1S/C18H14N2O3S/c1-24(21,22)15-6-7-16-17(10-15)20-18(19-16)13-4-2-12(3-5-13)14-8-9-23-11-14/h2-11H,1H3,(H,19,20) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329976
(6-(methylsulfonyl)-2-(4-(pyridin-2-yl)phenyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C19H15N3O2S/c1-25(23,24)15-9-10-17-18(12-15)22-19(21-17)14-7-5-13(6-8-14)16-4-2-3-11-20-16/h2-12H,1H3,(H,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329976
(6-(methylsulfonyl)-2-(4-(pyridin-2-yl)phenyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C19H15N3O2S/c1-25(23,24)15-9-10-17-18(12-15)22-19(21-17)14-7-5-13(6-8-14)16-4-2-3-11-20-16/h2-12H,1H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50329970
(4'-(6-(methylsulfonyl)-1H-benzo[d]imidazol-2-yl)bi...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccc(O)cc1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)17-10-11-18-19(12-17)22-20(21-18)15-4-2-13(3-5-15)14-6-8-16(23)9-7-14/h2-12,23H,1H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329975
(6-(methylsulfonyl)-2-(4-(pyridin-4-yl)phenyl)-1H-b...)Show SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C19H15N3O2S/c1-25(23,24)16-6-7-17-18(12-16)22-19(21-17)15-4-2-13(3-5-15)14-8-10-20-11-9-14/h2-12H,1H3,(H,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329980
(2-(6-(2-fluorophenyl)pyridin-3-yl)-1-methyl-5-(met...)Show SMILES Cn1c(nc2cc(ccc12)S(C)(=O)=O)-c1ccc(nc1)-c1ccccc1F Show InChI InChI=1S/C20H16FN3O2S/c1-24-19-10-8-14(27(2,25)26)11-18(19)23-20(24)13-7-9-17(22-12-13)15-5-3-4-6-16(15)21/h3-12H,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50329983
(2-(2'-methylbiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)Show SMILES Cc1ccccc1-c1ccc(cc1)-c1nc2ccc(cc2[nH]1)S(C)(=O)=O Show InChI InChI=1S/C21H18N2O2S/c1-14-5-3-4-6-18(14)15-7-9-16(10-8-15)21-22-19-12-11-17(26(2,24)25)13-20(19)23-21/h3-13H,1-2H3,(H,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 20: 6366-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.094
BindingDB Entry DOI: 10.7270/Q20V8D1P |
More data for this
Ligand-Target Pair | |
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