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TargetAcyl-CoA desaturase 1
LigandBDBM50329995
Substrate/Competitorn/a
Meas. Tech.ChEMBL_676020 (CHEMBL1272958)
IC50 95±n/a nM
Citation Powell, DARamtohul, YLebrun, MEOballa, RBhat, SFalgueyret, JPGuiral, SHuang, ZSkorey, KTawa, PZhang, L 2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors. Bioorg Med Chem Lett20:6366-9 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acyl-CoA desaturase 1
Name:Acyl-CoA desaturase 1
Synonyms:ACOD1_RAT | Acyl-CoA desaturase 1 | Scd | Scd1 | Stearoyl-CoA desaturase 1 (SCD1)
Type:Enzyme
Mol. Mass.:41485.97
Organism:Rattus norvegicus (Rat)
Description:P07308
Residue:358
Sequence:
MPAHMLQEISSSYTTTTTITEPPSGNLQNGREKMKKVPLYLEEDIRPEMREDIHDPSYQD
EEGPPPKLEYVWRNIILMALLHVGALYGITLIPSSKVYTLLWGIFYYLISALGITAGAHR
LWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSH
VGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGET
FLHSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYH
HAFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAVLARIKRTGDGSHKSS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50329995
n/a
NameBDBM50329995
Synonyms:2-(3'-chloro-2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-benzo[d]imidazole | CHEMBL1271875
TypeSmall organic molecule
Emp. Form.C20H14ClFN2O2S
Mol. Mass.400.854
SMILESCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(Cl)c1F
Structure
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