Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine deaminase (Homo sapiens (Human)) | BDBM50368778 (CHEMBL610668) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.41E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rhode Island Curated by ChEMBL | Assay Description Tested for inhibition against human plasma adenosine deaminase (ADA2) | J Med Chem 36: 4113-20 (1994) BindingDB Entry DOI: 10.7270/Q2B27VXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine deaminase (Homo sapiens (Human)) | BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | DrugBank PubMed | 2.18E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rhode Island Curated by ChEMBL | Assay Description Tested for binding constant against adenosine deaminase (ADA2) in human plasma | J Med Chem 36: 4113-20 (1994) BindingDB Entry DOI: 10.7270/Q2B27VXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | DrugBank PDB PubMed | n/a | n/a | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a |
University of Rhode Island Curated by ChEMBL | Assay Description Effective concentration required for cyclic AMP dependent inhibition of blood platelet aggregation for A2 receptor stimulation | J Med Chem 36: 4113-20 (1994) BindingDB Entry DOI: 10.7270/Q2B27VXH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |