Compile Data Set for Download or QSAR

Found 75 hits Enz. Inhib. hit(s) with all data for entry = 50040159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]NAM from mGluR5				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390029 (CHEMBL2069397) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClFN3O2/c19-13-3-1-2-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-6-4-14(20)5-7-15/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]NAM from mGluR5				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390029 (CHEMBL2069397) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClFN3O2/c19-13-3-1-2-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-6-4-14(20)5-7-15/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]NAM from mGluR5				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390036 (CHEMBL2071574) Show SMILES Cc1ccccc1N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O2/c1-12-5-2-3-8-16(12)23-11-14(10-17(23)24)19-21-18(22-25-19)13-6-4-7-15(20)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390066 (CHEMBL2069396) Show SMILES Clc1cccc(c1)-c1noc(CCN2C(=O)CCc3ccc(Cl)cc23)n1 Show InChI InChI=1S/C19H15Cl2N3O2/c20-14-3-1-2-13(10-14)19-22-17(26-23-19)8-9-24-16-11-15(21)6-4-12(16)5-7-18(24)25/h1-4,6,10-11H,5,7-9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390039 (CHEMBL2071577) Show SMILES COc1ccccc1N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3/c1-25-16-8-3-2-7-15(16)23-11-13(10-17(23)24)19-21-18(22-26-19)12-5-4-6-14(20)9-12/h2-9,13H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390037 (CHEMBL2071575) Show SMILES Clc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccccc1Cl Show InChI InChI=1S/C18H13Cl2N3O2/c19-13-5-3-4-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-7-2-1-6-14(15)20/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390035 (CHEMBL2071573) Show SMILES COc1cccc(c1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3/c1-25-16-7-3-6-15(10-16)23-11-13(9-17(23)24)19-21-18(22-26-19)12-4-2-5-14(20)8-12/h2-8,10,13H,9,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390064 (CHEMBL2069394) Show SMILES Clc1cccc(c1)-c1noc(CN2C(=O)COc3ccccc23)n1 Show InChI InChI=1S/C17H12ClN3O3/c18-12-5-3-4-11(8-12)17-19-15(24-20-17)9-21-13-6-1-2-7-14(13)23-10-16(21)22/h1-8H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390065 (CHEMBL2069395) Show SMILES Clc1cccc(c1)-c1noc(CCN2C(=O)COc3ccccc23)n1 Show InChI InChI=1S/C18H14ClN3O3/c19-13-5-3-4-12(10-13)18-20-16(25-21-18)8-9-22-14-6-1-2-7-15(14)24-11-17(22)23/h1-7,10H,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390069 (CHEMBL2069389) Show SMILES CC(C)CN1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C16H18ClN3O2/c1-10(2)8-20-9-12(7-14(20)21)16-18-15(19-22-16)11-4-3-5-13(17)6-11/h3-6,10,12H,7-9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390062 (CHEMBL2069392) Show SMILES Clc1cccc(c1)-c1noc(Cn2c3ccccc3sc2=O)n1 Show InChI InChI=1S/C16H10ClN3O2S/c17-11-5-3-4-10(8-11)15-18-14(22-19-15)9-20-12-6-1-2-7-13(12)23-16(20)21/h1-8H,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390038 (CHEMBL2071576) Show SMILES Fc1ccccc1N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClFN3O2/c19-13-5-3-4-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-7-2-1-6-14(15)20/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390034 (CHEMBL2071572) Show SMILES Clc1cccc(c1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13Cl2N3O2/c19-13-4-1-3-11(7-13)17-21-18(25-22-17)12-8-16(24)23(10-12)15-6-2-5-14(20)9-15/h1-7,9,12H,8,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390068 (CHEMBL2069388) Show SMILES C[C@@H](N1C[C@@H](CC1=O)c1nc(no1)-c1cccc(Cl)c1)c1ccccc1 |r| Show InChI InChI=1S/C20H18ClN3O2/c1-13(14-6-3-2-4-7-14)24-12-16(11-18(24)25)20-22-19(23-26-20)15-8-5-9-17(21)10-15/h2-10,13,16H,11-12H2,1H3/t13-,16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390063 (CHEMBL2069393) Show SMILES Clc1cccc(c1)-c1noc(Cn2c3ccccc3oc2=O)n1 Show InChI InChI=1S/C16H10ClN3O3/c17-11-5-3-4-10(8-11)15-18-14(23-19-15)9-20-12-6-1-2-7-13(12)22-16(20)21/h1-8H,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390030 (CHEMBL2071571) Show SMILES Cc1cccc(c1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O2/c1-12-4-2-7-16(8-12)23-11-14(10-17(23)24)19-21-18(22-25-19)13-5-3-6-15(20)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390031 (CHEMBL2071570) Show SMILES COc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3/c1-25-16-7-5-15(6-8-16)23-11-13(10-17(23)24)19-21-18(22-26-19)12-3-2-4-14(20)9-12/h2-9,13H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390067 (CHEMBL2069387) Show SMILES Fc1ccc(CN2CC(CC2=O)c2nc(no2)-c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C19H15ClFN3O2/c20-15-3-1-2-13(8-15)18-22-19(26-23-18)14-9-17(25)24(11-14)10-12-4-6-16(21)7-5-12/h1-8,14H,9-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390029 (CHEMBL2069397) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClFN3O2/c19-13-3-1-2-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-6-4-14(20)5-7-15/h1-8,12H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390029 (CHEMBL2069397) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClFN3O2/c19-13-3-1-2-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-6-4-14(20)5-7-15/h1-8,12H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390032 (CHEMBL2071569) Show SMILES Clc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13Cl2N3O2/c19-13-4-6-15(7-5-13)23-10-12(9-16(23)24)18-21-17(22-25-18)11-2-1-3-14(20)8-11/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390041 (CHEMBL2071579) Show SMILES Cc1ccc(cc1C)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H18ClN3O2/c1-12-6-7-17(8-13(12)2)24-11-15(10-18(24)25)20-22-19(23-26-20)14-4-3-5-16(21)9-14/h3-9,15H,10-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390033 (CHEMBL2071568) Show SMILES Cc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O2/c1-12-5-7-16(8-6-12)23-11-14(10-17(23)24)19-21-18(22-25-19)13-3-2-4-15(20)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390029 (CHEMBL2069397) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClFN3O2/c19-13-3-1-2-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-6-4-14(20)5-7-15/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390040 (CHEMBL2071578) Show SMILES Clc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H12Cl3N3O2/c19-12-3-1-2-10(6-12)17-22-18(26-23-17)11-7-16(25)24(9-11)13-4-5-14(20)15(21)8-13/h1-6,8,11H,7,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of CYP1A2				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2C19				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390030 (CHEMBL2071571) Show SMILES Cc1cccc(c1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O2/c1-12-4-2-7-16(8-12)23-11-14(10-17(23)24)19-21-18(22-25-19)13-5-3-6-15(20)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390031 (CHEMBL2071570) Show SMILES COc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3/c1-25-16-7-5-15(6-8-16)23-11-13(10-17(23)24)19-21-18(22-26-19)12-3-2-4-14(20)9-12/h2-9,13H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390032 (CHEMBL2071569) Show SMILES Clc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13Cl2N3O2/c19-13-4-6-15(7-5-13)23-10-12(9-16(23)24)18-21-17(22-25-18)11-2-1-3-14(20)8-11/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390033 (CHEMBL2071568) Show SMILES Cc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O2/c1-12-5-7-16(8-6-12)23-11-14(10-17(23)24)19-21-18(22-25-19)13-3-2-4-15(20)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390034 (CHEMBL2071572) Show SMILES Clc1cccc(c1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13Cl2N3O2/c19-13-4-1-3-11(7-13)17-21-18(25-22-17)12-8-16(24)23(10-12)15-6-2-5-14(20)9-15/h1-7,9,12H,8,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390035 (CHEMBL2071573) Show SMILES COc1cccc(c1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3/c1-25-16-7-3-6-15(10-16)23-11-13(9-17(23)24)19-21-18(22-26-19)12-4-2-5-14(20)8-12/h2-8,10,13H,9,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390036 (CHEMBL2071574) Show SMILES Cc1ccccc1N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O2/c1-12-5-2-3-8-16(12)23-11-14(10-17(23)24)19-21-18(22-25-19)13-6-4-7-15(20)9-13/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390037 (CHEMBL2071575) Show SMILES Clc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccccc1Cl Show InChI InChI=1S/C18H13Cl2N3O2/c19-13-5-3-4-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-7-2-1-6-14(15)20/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390038 (CHEMBL2071576) Show SMILES Fc1ccccc1N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClFN3O2/c19-13-5-3-4-11(8-13)17-21-18(25-22-17)12-9-16(24)23(10-12)15-7-2-1-6-14(15)20/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390039 (CHEMBL2071577) Show SMILES COc1ccccc1N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3/c1-25-16-8-3-2-7-15(16)23-11-13(10-17(23)24)19-21-18(22-26-19)12-5-4-6-14(20)9-12/h2-9,13H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390040 (CHEMBL2071578) Show SMILES Clc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H12Cl3N3O2/c19-12-3-1-2-10(6-12)17-22-18(26-23-17)11-7-16(25)24(9-11)13-4-5-14(20)15(21)8-13/h1-6,8,11H,7,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390041 (CHEMBL2071579) Show SMILES Cc1ccc(cc1C)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H18ClN3O2/c1-12-6-7-17(8-13(12)2)24-11-15(10-18(24)25)20-22-19(23-26-20)14-4-3-5-16(21)9-14/h3-9,15H,10-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390042 (CHEMBL2071580) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1ccccc1 Show InChI InChI=1S/C18H14FN3O2/c19-14-6-8-15(9-7-14)22-11-13(10-16(22)23)18-20-17(21-24-18)12-4-2-1-3-5-12/h1-9,13H,10-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390043 (CHEMBL2071581) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(F)c1 Show InChI InChI=1S/C18H13F2N3O2/c19-13-4-6-15(7-5-13)23-10-12(9-16(23)24)18-21-17(22-25-18)11-2-1-3-14(20)8-11/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	88	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390028 (CHEMBL2069398) Show SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O2/c1-12-3-2-4-13(9-12)18-21-19(25-22-18)14-10-17(24)23(11-14)16-7-5-15(20)6-8-16/h2-9,14H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12.5	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390044 (CHEMBL2071582) Show SMILES COc1cccc(c1)-c1noc(n1)C1CN(C(=O)C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN3O3/c1-25-16-4-2-3-12(9-16)18-21-19(26-22-18)13-10-17(24)23(11-13)15-7-5-14(20)6-8-15/h2-9,13H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50390045 (CHEMBL2071583) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)c1nc(no1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H13F4N3O2/c20-14-4-6-15(7-5-14)26-10-12(9-16(26)27)18-24-17(25-28-18)11-2-1-3-13(8-11)19(21,22)23/h1-8,12H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293A cells assessed as stimulation of glutamate-induced calcium flux by FLIPR method				Bioorg Med Chem Lett 22: 5658-62 (2012) Article DOI: 10.1016/j.bmcl.2012.06.094 BindingDB Entry DOI: 10.7270/Q2348MF7
					More data for this Ligand-Target Pair

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