Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with all data for entry = 50040309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50330763 (2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...) Show SMILES COc1ccc(cc1)-c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O/c1-19-14-9-7-13(8-10-14)16-17-11-15(18-16)12-5-3-2-4-6-12/h2-11H,1H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392415 (CHEMBL402642) Show SMILES C(Oc1ccccc1)c1cn(nn1)-c1ccccc1 Show InChI InChI=1S/C15H13N3O/c1-3-7-14(8-4-1)18-11-13(16-17-18)12-19-15-9-5-2-6-10-15/h1-11H,12H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392416 (CHEMBL2151778) Show SMILES C(COc1ccccc1)Cc1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C18H19N3O/c1-3-8-16(9-4-1)14-21-15-17(19-20-21)10-7-13-22-18-11-5-2-6-12-18/h1-6,8-9,11-12,15H,7,10,13-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50133778 (2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...) Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392417 (CHEMBL2151781) Show SMILES C(COc1ccccc1)Cc1cn(CCc2ccccc2)nn1 Show InChI InChI=1S/C19H21N3O/c1-3-8-17(9-4-1)13-14-22-16-18(20-21-22)10-7-15-23-19-11-5-2-6-12-19/h1-6,8-9,11-12,16H,7,10,13-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392418 (CHEMBL2151783) Show SMILES O=C(Cn1cc(CCCOc2ccccc2)nn1)c1ccccc1 Show InChI InChI=1S/C19H19N3O2/c23-19(16-8-3-1-4-9-16)15-22-14-17(20-21-22)10-7-13-24-18-11-5-2-6-12-18/h1-6,8-9,11-12,14H,7,10,13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50351882 (CHEMBL1825043) Show SMILES C(c1ccccc1)n1cc(nn1)-c1ccccc1 Show InChI InChI=1S/C15H13N3/c1-3-7-13(8-4-1)11-18-12-15(16-17-18)14-9-5-2-6-10-14/h1-10,12H,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair