BindingDB PrimarySearch

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 50041480
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50237601 (CHEMBL411941 \| CycloRGDfV \| [(2S,5R,8S,11S)-5-Benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50100971 (CHEMBL40929 \| N-(3,5-dichlorophenyl)imidodicarboni...) Show SMILES NC(=N)N=C(N)Nc1cc(Cl)cc(Cl)c1 \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50100977 (3,4-dichloro-phenylbiguanide \| CHEMBL41433 \| N-(3,...) Show SMILES NC(=N)N=C(N)Nc1ccc(Cl)c(Cl)c1 \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195106 (CHEMBL220928 \| N-[3,5-bis(trifluoromethyl)phenyl]i...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195100 ((Z)-N-(2,6-dimethoxypyrimidin-4-yl)-4-((1-(4-iodop...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195099 (CHEMBL220979 \| N-(2,4-dichlorophenyl)imidodicarbon...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50154223 (CHEMBL185802 \| N-(2,3-dichlorophenyl)imidodicarbon...) Show SMILES NC(=N)N=C(N)Nc1cccc(Cl)c1Cl \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195101 (CHEMBL222122 \| N-(3-chloro-4-fluorophenyl)imidodic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195089 (CHEMBL221952 \| N-(2,5-dichlorophenyl)imidodicarbon...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195088 (CHEMBL219378 \| N-{4-[(trifluoromethyl)thio]phenyl}...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195102 (CHEMBL219484 \| N-[2-chloro-5-(trifluoromethyl)phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195090 (CHEMBL385111 \| {2-bromo-6-ethoxy-4-[8-methyl-3-oxo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195096 (2-(2,4-dichloro-phenoxy)-N-[4-(2,6-dimethoxy-pyrim...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.37E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195094 ((Z)-4-(4-(4-(benzoyloxy)-3-methoxybenzylidene)-3-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50053595 (4-Chloro-Phenyl biguanide \| 4-Chlorophenylbiguanid...) Show SMILES NC(=N)N=C(N)Nc1ccc(Cl)cc1 \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195098 (CHEMBL386940 \| N-(2-{2-hydroxy-4-[2-(4-methyl-4H-[...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195093 (CHEMBL221306 \| N-{4-[(difluoromethyl)thio]phenyl}i...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195104 (2-(4-(5-(4-nitrophenoxy)-1,3-dioxoisoindolin-2-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50053615 (3-Chloro-Phenyl biguanide \| CHEMBL13790 \| N-(3-chl...) Show SMILES NC(=N)N=C(N)Nc1cccc(Cl)c1 \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.91E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195095 (CHEMBL221309 \| ethyl 3-{[{[amino(imino)methyl]amin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195097 (CHEMBL375650 \| N-(2-ethoxyphenyl)imidodicarbonimid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50053629 (2-Chloro-Phenyl biguanide \| CHEMBL42752 \| N-(2-chl...) Show SMILES NC(=N)N=C(N)Nc1ccccc1Cl \|w:3.2\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50053596 (1-phenylbiguanide \| CHEMBL13791 \| N-phenylimidodic...) Show SMILES NC(=N)NC(N)=Nc1ccccc1 \|w:6.6\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195103 (CHEMBL221253 \| N-[3-(methylthio)phenyl]imidodicarb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195091 (CHEMBL375434 \| N-(5-chloro-2-methylphenyl)imidodic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50195105 (CHEMBL221310 \| N-[2-(methylthio)phenyl]imidodicarb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin				Bioorg Med Chem Lett 16: 5878-82 (2006) Article DOI: 10.1016/j.bmcl.2006.08.061 BindingDB Entry DOI: 10.7270/Q2W66N0W
					More data for this Ligand-Target Pair