Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211284 (CHEMBL3959435) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211284 (CHEMBL3959435) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211282 (CHEMBL308493) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211280 (S007-1558 (S)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM82258 (CAS_114798-26-4 | Losartan | NSC_3961) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM82258 (CAS_114798-26-4 | Losartan | NSC_3961) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211282 (CHEMBL308493) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211280 (S007-1558 (S)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50016900 ((E)-N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-induced platelet aggregation preincubated for 60 sec ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50016900 ((E)-N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 60... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211282 (CHEMBL308493) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211284 (CHEMBL3959435) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 5.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211283 (CHEMBL2263356) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211283 (CHEMBL2263356) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.26E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM82258 (CAS_114798-26-4 | Losartan | NSC_3961) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.58E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211280 (S007-1558 (S)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.81E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211283 (CHEMBL2263356) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi... | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211287 (CHEMBL3957185) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Binding affinity to GP6 receptor (unknown origin) by NMR method | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211285 (CHEMBL3948507) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Binding affinity to GP6 receptor (unknown origin) by NMR method | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet glycoprotein VI (Homo sapiens (Human)) | BDBM50211281 (CHEMBL3894250) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.50E+5 | n/a | n/a | n/a | n/a | n/a |
Academy of Scientific and Innovative Research Curated by ChEMBL | Assay Description Binding affinity to GP6 receptor (unknown origin) by NMR method | J Med Chem 60: 322-337 (2017) Article DOI: 10.1021/acs.jmedchem.6b01360 BindingDB Entry DOI: 10.7270/Q24T6MJ1 | |||||||||||
More data for this Ligand-Target Pair |