Compile Data Set for Download or QSAR

Found 50 hits Enz. Inhib. hit(s) with all data for entry = 50048923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50359505 (CHEMBL1182312) Show SMILES NCCc1ccc(Oc2ccc(O)cc2)c(I)c1 Show InChI InChI=1S/C14H14INO2/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12/h1-6,9,17H,7-8,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal HA-tagged/C-terminal FLAG-tagged TAAR1 expressed in CHOK1 cells assessed as increase in cAMP a...				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50053629 (2-Chloro-Phenyl biguanide | CHEMBL42752 | N-(2-chl...) Show SMILES NC(=N)N=C(N)Nc1ccccc1Cl |w:3.2| Show InChI InChI=1S/C8H10ClN5/c9-5-3-1-2-4-6(5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227351 (CHEMBL3628706) Show SMILES NC(=N)NC(=N)NCc1ccccc1 Show InChI InChI=1S/C9H13N5/c10-8(11)14-9(12)13-6-7-4-2-1-3-5-7/h1-5H,6H2,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227824 (CHEMBL4088689) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(Cl)c1 Show InChI InChI=1S/C9H12ClN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227825 (CHEMBL4060464) Show SMILES Cl.Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN5/c10-7-3-1-6(2-4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227826 (CHEMBL4069147) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(F)c1 Show InChI InChI=1S/C9H12FN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227828 (CHEMBL4068661) Show SMILES Cl.Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(Br)c1 Show InChI InChI=1S/C9H12BrN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227829 (CHEBI:8455 | CHLOROGUANIDE | Proguanil) Show SMILES CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C11H16ClN5/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9/h3-7H,1-2H3,(H5,13,14,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50053629 (2-Chloro-Phenyl biguanide | CHEMBL42752 | N-(2-chl...) Show SMILES NC(=N)N=C(N)Nc1ccccc1Cl |w:3.2| Show InChI InChI=1S/C8H10ClN5/c9-5-3-1-2-4-6(5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50053615 (3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...) Show SMILES NC(=N)N=C(N)Nc1cccc(Cl)c1 |w:3.2| Show InChI InChI=1S/C8H10ClN5/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50100977 (3,4-dichloro-phenylbiguanide | CHEMBL41433 | N-(3,...) Show SMILES NC(=N)N=C(N)Nc1ccc(Cl)c(Cl)c1 |w:3.2| Show InChI InChI=1S/C8H9Cl2N5/c9-5-2-1-4(3-6(5)10)14-8(13)15-7(11)12/h1-3H,(H6,11,12,13,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227830 (CHEMBL4099661) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\c1cccc(F)c1 Show InChI InChI=1S/C8H10FN5/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227833 (CHEMBL4088381) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\c1ccc(cc1)-[#7+](-[#8-])=O Show InChI InChI=1S/C8H10N6O2/c9-7(10)13-8(11)12-5-1-3-6(4-2-5)14(15)16/h1-4H,(H6,9,10,11,12,13)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227834 (CHEMBL4077681) Show SMILES [#6]-[#8]-c1ccc(cc1)\[#7]=[#6](/[#7])\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C9H13N5O/c1-15-7-4-2-6(3-5-7)13-9(12)14-8(10)11/h2-5H,1H3,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227351 (CHEMBL3628706) Show SMILES NC(=N)NC(=N)NCc1ccccc1 Show InChI InChI=1S/C9H13N5/c10-8(11)14-9(12)13-6-7-4-2-1-3-5-7/h1-5H,6H2,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227824 (CHEMBL4088689) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(Cl)c1 Show InChI InChI=1S/C9H12ClN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227825 (CHEMBL4060464) Show SMILES Cl.Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN5/c10-7-3-1-6(2-4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227835 (CHEMBL4096403) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C9H11Cl2N5/c10-6-2-1-5(3-7(6)11)4-15-9(14)16-8(12)13/h1-3H,4H2,(H6,12,13,14,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227828 (CHEMBL4068661) Show SMILES Cl.Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(Br)c1 Show InChI InChI=1S/C9H12BrN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227836 (CHEMBL4076103) Show SMILES Cl.Cl.[#6]-[#8]-c1ccc(-[#6]\[#7]=[#6](/[#7])\[#7]=[#6](\[#7])-[#7])cc1 Show InChI InChI=1S/C10H15N5O/c1-16-8-4-2-7(3-5-8)6-14-10(13)15-9(11)12/h2-5H,6H2,1H3,(H6,11,12,13,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227838 (CHEMBL4102503) Show SMILES Cl.Cl.[#6]-[#8]-c1ccc(-[#6]\[#7]=[#6](/[#7])\[#7]=[#6](\[#7])-[#7])cc1-[#8]-[#6] Show InChI InChI=1S/C11H17N5O2/c1-17-8-4-3-7(5-9(8)18-2)6-15-11(14)16-10(12)13/h3-5H,6H2,1-2H3,(H6,12,13,14,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227839 (CHEMBL4094764) Show SMILES Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]1 Show InChI InChI=1S/C9H19N5/c10-8(11)14-9(12)13-7-5-3-1-2-4-6-7/h7H,1-6H2,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227840 (CHEMBL2079013) Show SMILES NC(=N)NC(=N)NC12CC3CC(CC(C3)C1)C2 |TLB:6:7:10:14.12.13,THB:12:11:8:14.13.15,12:13:10.11.16:8,15:13:10:16.7.8,15:7:10:14.12.13| Show InChI InChI=1S/C12H21N5/c13-10(14)16-11(15)17-12-4-7-1-8(5-12)3-9(2-7)6-12/h7-9H,1-6H2,(H6,13,14,15,16,17)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227841 (ABOB | Moroxydine | SKF-8898A) Show SMILES NC(=N)\N=C(/N)N1CCOCC1 Show InChI InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM18792 (1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-...) Show SMILES CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1 |t:3,6| Show InChI InChI=1S/C11H14ClN5/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8/h3-6H,1-2H3,(H4,13,14,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50378363 (CHEMBL574656) Show SMILES NC1=NC2(CCCCC2)N(C(N)=N1)c1ccc(Cl)cc1 |c:12,t:1| Show InChI InChI=1S/C14H18ClN5/c15-10-4-6-11(7-5-10)20-13(17)18-12(16)19-14(20)8-2-1-3-9-14/h4-7H,1-3,8-9H2,(H4,16,17,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM18069 (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) Show SMILES COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC Show InChI InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50053629 (2-Chloro-Phenyl biguanide | CHEMBL42752 | N-(2-chl...) Show SMILES NC(=N)N=C(N)Nc1ccccc1Cl |w:3.2| Show InChI InChI=1S/C8H10ClN5/c9-5-3-1-2-4-6(5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50053595 (4-Chloro-Phenyl biguanide | 4-Chlorophenylbiguanid...) Show SMILES NC(=N)N=C(N)Nc1ccc(Cl)cc1 |w:3.2| Show InChI InChI=1S/C8H10ClN5/c9-5-1-3-6(4-2-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50053630 (4-Methyl-Phenyl biguanide | CHEMBL291064 | N-(4-me...) Show SMILES Cc1ccc(NC(N)=NC(N)=N)cc1 |w:8.8| Show InChI InChI=1S/C9H13N5/c1-6-2-4-7(5-3-6)13-9(12)14-8(10)11/h2-5H,1H3,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227975 (CHEMBL4087775) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccccc1Cl Show InChI InChI=1S/C9H12ClN5/c10-7-4-2-1-3-6(7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227824 (CHEMBL4088689) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(Cl)c1 Show InChI InChI=1S/C9H12ClN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	97	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227835 (CHEMBL4096403) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C9H11Cl2N5/c10-6-2-1-5(3-7(6)11)4-15-9(14)16-8(12)13/h1-3H,4H2,(H6,12,13,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227826 (CHEMBL4069147) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(F)c1 Show InChI InChI=1S/C9H12FN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227828 (CHEMBL4068661) Show SMILES Cl.Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(Br)c1 Show InChI InChI=1S/C9H12BrN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50053595 (4-Chloro-Phenyl biguanide | 4-Chlorophenylbiguanid...) Show SMILES NC(=N)N=C(N)Nc1ccc(Cl)cc1 |w:3.2| Show InChI InChI=1S/C8H10ClN5/c9-5-1-3-6(4-2-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227835 (CHEMBL4096403) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C9H11Cl2N5/c10-6-2-1-5(3-7(6)11)4-15-9(14)16-8(12)13/h1-3H,4H2,(H6,12,13,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50053596 (1-phenylbiguanide | CHEMBL13791 | N-phenylimidodic...) Show SMILES NC(=N)NC(N)=Nc1ccccc1 |w:6.6| Show InChI InChI=1S/C8H11N5/c9-7(10)13-8(11)12-6-4-2-1-3-5-6/h1-5H,(H6,9,10,11,12,13)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50053595 (4-Chloro-Phenyl biguanide | 4-Chlorophenylbiguanid...) Show SMILES NC(=N)N=C(N)Nc1ccc(Cl)cc1 |w:3.2| Show InChI InChI=1S/C8H10ClN5/c9-5-1-3-6(4-2-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50053630 (4-Methyl-Phenyl biguanide | CHEMBL291064 | N-(4-me...) Show SMILES Cc1ccc(NC(N)=NC(N)=N)cc1 |w:8.8| Show InChI InChI=1S/C9H13N5/c1-6-2-4-7(5-3-6)13-9(12)14-8(10)11/h2-5H,1H3,(H6,10,11,12,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227975 (CHEMBL4087775) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccccc1Cl Show InChI InChI=1S/C9H12ClN5/c10-7-4-2-1-3-6(7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227826 (CHEMBL4069147) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1cccc(F)c1 Show InChI InChI=1S/C9H12FN5/c10-7-3-1-2-6(4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227979 (CHEMBL4084561) Show SMILES Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-1-[#6]-[#6]-[#6]-[#6]1 Show InChI InChI=1S/C7H15N5/c8-6(9)12-7(10)11-5-3-1-2-4-5/h5H,1-4H2,(H6,8,9,10,11,12)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM50227829 (CHEBI:8455 | CHLOROGUANIDE | Proguanil) Show SMILES CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C11H16ClN5/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9/h3-7H,1-2H3,(H5,13,14,15,16,17)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 5 (Mus musculus)	BDBM18512 (5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...) Show SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227975 (CHEMBL4087775) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccccc1Cl Show InChI InChI=1S/C9H12ClN5/c10-7-4-2-1-3-6(7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227351 (CHEMBL3628706) Show SMILES NC(=N)NC(=N)NCc1ccccc1 Show InChI InChI=1S/C9H13N5/c10-8(11)14-9(12)13-6-7-4-2-1-3-5-7/h1-5H,6H2,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227825 (CHEMBL4060464) Show SMILES Cl.Cl.[#7]\[#6](-[#7])=[#7]\[#6](\[#7])=[#7]\[#6]-c1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN5/c10-7-3-1-6(2-4-7)5-14-9(13)15-8(11)12/h1-4H,5H2,(H6,11,12,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM50227829 (CHEBI:8455 | CHLOROGUANIDE | Proguanil) Show SMILES CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C11H16ClN5/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9/h3-7H,1-2H3,(H5,13,14,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50053630 (4-Methyl-Phenyl biguanide | CHEMBL291064 | N-(4-me...) Show SMILES Cc1ccc(NC(N)=NC(N)=N)cc1 |w:8.8| Show InChI InChI=1S/C9H13N5/c1-6-2-4-7(5-3-6)13-9(12)14-8(10)11/h2-5H,1H3,(H6,10,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay				Eur J Med Chem 127: 781-792 (2017) Article DOI: 10.1016/j.ejmech.2016.10.058 BindingDB Entry DOI: 10.7270/Q2C24ZPS
					More data for this Ligand-Target Pair