Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136294 (US8853212, DDP-4 Inhibitor 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136295 (US8853212, DDP-4 Inhibitor 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136291 (US8853212, DDP-4 Inhibitor 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136293 (US8853212, DDP-4 Inhibitor 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136298 (US8853212, DDP-4 Inhibitor 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136297 (US8853212, DDP-4 Inhibitor 13) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136296 (US8853212, DDP-4 Inhibitor 12) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136300 (US8853212, DDP-4 Inhibitor 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136292 (US8853212, DDP-4 Inhibitor 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136299 (US8853212, DDP-4 Inhibitor 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136285 (US8853212, DDP-4 Inhibitor 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136290 (US8853212, DDP-4 Inhibitor 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136286 (US8853212, DDP-4 Inhibitor 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136301 (US8853212, DDP-4 Inhibitor 17) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136287 (US8853212, DDP-4 Inhibitor 3 | US8853212, DDP-4 I...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136287 (US8853212, DDP-4 Inhibitor 3 | US8853212, DDP-4 I...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 49 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM136289 (US8853212, DDP-4 Inhibitor 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 119 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T... | US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4 | |||||||||||
More data for this Ligand-Target Pair |