Compile Data Set for Download or QSAR

Found 205 hits Enz. Inhib. hit(s) with all data for entry = 6700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM148254 (US8962630, 63) Show SMILES CC(C)N1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C26H36N8O/c1-18(2)32-11-13-33(14-12-32)21-9-10-23(27-17-21)29-26-28-16-19-15-22(25(35)31(3)4)34(24(19)30-26)20-7-5-6-8-20/h9-10,15-18,20H,5-8,11-14H2,1-4H3,(H,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM148264 (7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)p...) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1 Show InChI InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM148218 (US8962630, 26) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CCO)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C25H34N8O2/c1-30(2)24(35)21-15-18-16-27-25(29-23(18)33(21)19-5-3-4-6-19)28-22-8-7-20(17-26-22)32-11-9-31(10-12-32)13-14-34/h7-8,15-17,19,34H,3-6,9-14H2,1-2H3,(H,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148210 (US8962630, 18) Show SMILES C(N1CCNCC1)c1ccc(Nc2ncc3cc(-c4cnco4)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C24H28N8O/c1-2-4-19(3-1)32-20(21-14-26-16-33-21)11-18-13-28-24(30-23(18)32)29-22-6-5-17(12-27-22)15-31-9-7-25-8-10-31/h5-6,11-14,16,19,25H,1-4,7-10,15H2,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148203 (US8962630, 11) Show SMILES C1CCC(C1)n1c(cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc12)-c1cnco1 Show InChI InChI=1S/C23H26N8O/c1-2-4-17(3-1)31-19(20-14-25-15-32-20)11-16-12-27-23(29-22(16)31)28-21-6-5-18(13-26-21)30-9-7-24-8-10-30/h5-6,11-15,17,24H,1-4,7-10H2,(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148238 (US8962630, 47) Show SMILES CN(C)C1CCN(CC1)c1ccc(Nc2ncc3cc(C#N)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C24H30N8/c1-30(2)18-9-11-31(12-10-18)20-7-8-22(26-16-20)28-24-27-15-17-13-21(14-25)32(23(17)29-24)19-5-3-4-6-19/h7-8,13,15-16,18-19H,3-6,9-12H2,1-2H3,(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM148210 (US8962630, 18) Show SMILES C(N1CCNCC1)c1ccc(Nc2ncc3cc(-c4cnco4)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C24H28N8O/c1-2-4-19(3-1)32-20(21-14-26-16-33-21)11-18-13-28-24(30-23(18)32)29-22-6-5-17(12-27-22)15-31-9-7-25-8-10-31/h5-6,11-14,16,19,25H,1-4,7-10,15H2,(H,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM148226 (US8962630, 35) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCC(CCO)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C26H35N7O2/c1-31(2)25(35)22-15-19-16-28-26(30-24(19)33(22)20-5-3-4-6-20)29-23-8-7-21(17-27-23)32-12-9-18(10-13-32)11-14-34/h7-8,15-18,20,34H,3-6,9-14H2,1-2H3,(H,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM148203 (US8962630, 11) Show SMILES C1CCC(C1)n1c(cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc12)-c1cnco1 Show InChI InChI=1S/C23H26N8O/c1-2-4-17(3-1)31-19(20-14-25-15-32-20)11-16-12-27-23(29-22(16)31)28-21-6-5-18(13-26-21)30-9-7-24-8-10-30/h5-6,11-15,17,24H,1-4,7-10H2,(H,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148226 (US8962630, 35) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCC(CCO)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C26H35N7O2/c1-31(2)25(35)22-15-19-16-28-26(30-24(19)33(22)20-5-3-4-6-20)29-23-8-7-21(17-27-23)32-12-9-18(10-13-32)11-14-34/h7-8,15-18,20,34H,3-6,9-14H2,1-2H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM148232 (US8962630, 41) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)C(=O)N(C)CCN)nc2n1C1CCCC1 Show InChI InChI=1S/C23H30N8O2/c1-29(2)22(33)18-12-16-14-26-23(28-20(16)31(18)17-6-4-5-7-17)27-19-9-8-15(13-25-19)21(32)30(3)11-10-24/h8-9,12-14,17H,4-7,10-11,24H2,1-3H3,(H,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM148199 (US8962630, 8) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCCNCC3)nc2n1C1CCCC1 Show InChI InChI=1S/C24H32N8O/c1-30(2)23(33)20-14-17-15-27-24(29-22(17)32(20)18-6-3-4-7-18)28-21-9-8-19(16-26-21)31-12-5-10-25-11-13-31/h8-9,14-16,18,25H,3-7,10-13H2,1-2H3,(H,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM148238 (US8962630, 47) Show SMILES CN(C)C1CCN(CC1)c1ccc(Nc2ncc3cc(C#N)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C24H30N8/c1-30(2)18-9-11-31(12-10-18)20-7-8-22(26-16-20)28-24-27-15-17-13-21(14-25)32(23(17)29-24)19-5-3-4-6-19/h7-8,13,15-16,18-19H,3-6,9-12H2,1-2H3,(H,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148202 (US8962630, 10A) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(CN4CC(O)C4)cn3)nc2n1C1CCCC1 Show InChI InChI=1S/C23H29N7O2/c1-28(2)22(32)19-9-16-11-25-23(27-21(16)30(19)17-5-3-4-6-17)26-20-8-7-15(10-24-20)12-29-13-18(31)14-29/h7-11,17-18,31H,3-6,12-14H2,1-2H3,(H,24,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148277 (US8962630, 87) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)C(=O)N3CCC(O)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C25H31N7O3/c1-30(2)24(35)20-13-17-15-27-25(29-22(17)32(20)18-5-3-4-6-18)28-21-8-7-16(14-26-21)23(34)31-11-9-19(33)10-12-31/h7-8,13-15,18-19,33H,3-6,9-12H2,1-2H3,(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148199 (US8962630, 8) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCCNCC3)nc2n1C1CCCC1 Show InChI InChI=1S/C24H32N8O/c1-30(2)23(33)20-14-17-15-27-24(29-22(17)32(20)18-6-3-4-7-18)28-21-9-8-19(16-26-21)31-12-5-10-25-11-13-31/h8-9,14-16,18,25H,3-7,10-13H2,1-2H3,(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM148202 (US8962630, 10A) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(CN4CC(O)C4)cn3)nc2n1C1CCCC1 Show InChI InChI=1S/C23H29N7O2/c1-28(2)22(32)19-9-16-11-25-23(27-21(16)30(19)17-5-3-4-6-17)26-20-8-7-15(10-24-20)12-29-13-18(31)14-29/h7-11,17-18,31H,3-6,12-14H2,1-2H3,(H,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148232 (US8962630, 41) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)C(=O)N(C)CCN)nc2n1C1CCCC1 Show InChI InChI=1S/C23H30N8O2/c1-29(2)22(33)18-12-16-14-26-23(28-20(16)31(18)17-6-4-5-7-17)27-19-9-8-15(13-25-19)21(32)30(3)11-10-24/h8-9,12-14,17H,4-7,10-11,24H2,1-3H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148194 (US8962630, 1) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccccn3)nc2n1C1CCCC1 Show InChI InChI=1S/C19H22N6O/c1-24(2)18(26)15-11-13-12-21-19(22-16-9-5-6-10-20-16)23-17(13)25(15)14-7-3-4-8-14/h5-6,9-12,14H,3-4,7-8H2,1-2H3,(H,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148264 (7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)p...) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1 Show InChI InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148268 (US8962630, 78) Show SMILES CCN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C25H34N8O/c1-4-31-11-13-32(14-12-31)20-9-10-22(26-17-20)28-25-27-16-18-15-21(24(34)30(2)3)33(23(18)29-25)19-7-5-6-8-19/h9-10,15-17,19H,4-8,11-14H2,1-3H3,(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148276 (US8962630, 86) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CCF)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C25H33FN8O/c1-31(2)24(35)21-15-18-16-28-25(30-23(18)34(21)19-5-3-4-6-19)29-22-8-7-20(17-27-22)33-13-11-32(10-9-26)12-14-33/h7-8,15-17,19H,3-6,9-14H2,1-2H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148218 (US8962630, 26) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CCO)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C25H34N8O2/c1-30(2)24(35)21-15-18-16-27-25(29-23(18)33(21)19-5-3-4-6-19)28-22-8-7-20(17-26-22)32-11-9-31(10-12-32)13-14-34/h7-8,15-17,19,34H,3-6,9-14H2,1-2H3,(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148206 (US8962630, 14) Show SMILES COCCN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C26H36N8O2/c1-31(2)25(35)22-16-19-17-28-26(30-24(19)34(22)20-6-4-5-7-20)29-23-9-8-21(18-27-23)33-12-10-32(11-13-33)14-15-36-3/h8-9,16-18,20H,4-7,10-15H2,1-3H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148283 (US8962630, 95) Show SMILES CC(C)OCCN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C28H40N8O2/c1-20(2)38-16-15-34-11-13-35(14-12-34)23-9-10-25(29-19-23)31-28-30-18-21-17-24(27(37)33(3)4)36(26(21)32-28)22-7-5-6-8-22/h9-10,17-20,22H,5-8,11-16H2,1-4H3,(H,29,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148224 (US8962630, 33) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CCOCCO)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C27H38N8O3/c1-32(2)26(37)23-17-20-18-29-27(31-25(20)35(23)21-5-3-4-6-21)30-24-8-7-22(19-28-24)34-11-9-33(10-12-34)13-15-38-16-14-36/h7-8,17-19,21,36H,3-6,9-16H2,1-2H3,(H,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148248 (US8962630, 57) Show SMILES C[C@@H](O)CN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 |r| Show InChI InChI=1S/C26H36N8O2/c1-18(35)17-32-10-12-33(13-11-32)21-8-9-23(27-16-21)29-26-28-15-19-14-22(25(36)31(2)3)34(24(19)30-26)20-6-4-5-7-20/h8-9,14-16,18,20,35H,4-7,10-13,17H2,1-3H3,(H,27,28,29,30)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148247 (US8962630, 56) Show SMILES C[C@H](O)CN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 |r| Show InChI InChI=1S/C26H36N8O2/c1-18(35)17-32-10-12-33(13-11-32)21-8-9-23(27-16-21)29-26-28-15-19-14-22(25(36)31(2)3)34(24(19)30-26)20-6-4-5-7-20/h8-9,14-16,18,20,35H,4-7,10-13,17H2,1-3H3,(H,27,28,29,30)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148261 (US8962630, 71) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC(C)(C)O)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C27H38N8O2/c1-27(2,37)18-33-11-13-34(14-12-33)21-9-10-23(28-17-21)30-26-29-16-19-15-22(25(36)32(3)4)35(24(19)31-26)20-7-5-6-8-20/h9-10,15-17,20,37H,5-8,11-14,18H2,1-4H3,(H,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148213 (US8962630, 21) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CCCO)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C26H36N8O2/c1-31(2)25(36)22-16-19-17-28-26(30-24(19)34(22)20-6-3-4-7-20)29-23-9-8-21(18-27-23)33-13-11-32(12-14-33)10-5-15-35/h8-9,16-18,20,35H,3-7,10-15H2,1-2H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148235 (US8962630, 44) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC(O)CO)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C26H36N8O3/c1-31(2)25(37)22-13-18-14-28-26(30-24(18)34(22)19-5-3-4-6-19)29-23-8-7-20(15-27-23)33-11-9-32(10-12-33)16-21(36)17-35/h7-8,13-15,19,21,35-36H,3-6,9-12,16-17H2,1-2H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148237 (US8962630, 46) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(C[C@@H](O)CO)CC3)nc2n1C1CCCC1 |r| Show InChI InChI=1S/C26H36N8O3/c1-31(2)25(37)22-13-18-14-28-26(30-24(18)34(22)19-5-3-4-6-19)29-23-8-7-20(15-27-23)33-11-9-32(10-12-33)16-21(36)17-35/h7-8,13-15,19,21,35-36H,3-6,9-12,16-17H2,1-2H3,(H,27,28,29,30)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148220 (US8962630, 29) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(C[C@H](O)CO)CC3)nc2n1C1CCCC1 |r| Show InChI InChI=1S/C26H36N8O3/c1-31(2)25(37)22-13-18-14-28-26(30-24(18)34(22)19-5-3-4-6-19)29-23-8-7-20(15-27-23)33-11-9-32(10-12-33)16-21(36)17-35/h7-8,13-15,19,21,35-36H,3-6,9-12,16-17H2,1-2H3,(H,27,28,29,30)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148269 (US8962630, 79) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC3)C3CCCC3)nc2n1C1CCCC1 Show InChI InChI=1S/C28H38N8O/c1-33(2)27(37)24-17-20-18-30-28(32-26(20)36(24)22-9-5-6-10-22)31-25-12-11-23(19-29-25)35-15-13-34(14-16-35)21-7-3-4-8-21/h11-12,17-19,21-22H,3-10,13-16H2,1-2H3,(H,29,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148254 (US8962630, 63) Show SMILES CC(C)N1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C26H36N8O/c1-18(2)32-11-13-33(14-12-32)21-9-10-23(27-17-21)29-26-28-16-19-15-22(25(35)31(3)4)34(24(19)30-26)20-7-5-6-8-20/h9-10,15-18,20H,5-8,11-14H2,1-4H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148227 (US8962630, 36) Show SMILES CC(CO)N1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C26H36N8O2/c1-18(17-35)32-10-12-33(13-11-32)21-8-9-23(27-16-21)29-26-28-15-19-14-22(25(36)31(2)3)34(24(19)30-26)20-6-4-5-7-20/h8-9,14-16,18,20,35H,4-7,10-13,17H2,1-3H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148287 (US8962630, 101) Show SMILES COC(=O)C(C)N1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C27H36N8O3/c1-18(26(37)38-4)33-11-13-34(14-12-33)21-9-10-23(28-17-21)30-27-29-16-19-15-22(25(36)32(2)3)35(24(19)31-27)20-7-5-6-8-20/h9-10,15-18,20H,5-8,11-14H2,1-4H3,(H,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148288 (US8962630, 103) Show SMILES CC(N1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1)C(O)=O Show InChI InChI=1S/C26H34N8O3/c1-17(25(36)37)32-10-12-33(13-11-32)20-8-9-22(27-16-20)29-26-28-15-18-14-21(24(35)31(2)3)34(23(18)30-26)19-6-4-5-7-19/h8-9,14-17,19H,4-7,10-13H2,1-3H3,(H,36,37)(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148259 (US8962630, 69) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC4CCCCC4)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C30H42N8O/c1-35(2)29(39)26-18-23-19-32-30(34-28(23)38(26)24-10-6-7-11-24)33-27-13-12-25(20-31-27)37-16-14-36(15-17-37)21-22-8-4-3-5-9-22/h12-13,18-20,22,24H,3-11,14-17,21H2,1-2H3,(H,31,32,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148281 (US8962630, 92) Show SMILES CC(C)CN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C27H38N8O/c1-19(2)18-33-11-13-34(14-12-33)22-9-10-24(28-17-22)30-27-29-16-20-15-23(26(36)32(3)4)35(25(20)31-27)21-7-5-6-8-21/h9-10,15-17,19,21H,5-8,11-14,18H2,1-4H3,(H,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148285 (US8962630, 99) Show SMILES CCC(C)CN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C28H40N8O/c1-5-20(2)19-34-12-14-35(15-13-34)23-10-11-25(29-18-23)31-28-30-17-21-16-24(27(37)33(3)4)36(26(21)32-28)22-8-6-7-9-22/h10-11,16-18,20,22H,5-9,12-15,19H2,1-4H3,(H,29,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148279 (US8962630, 90) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)CC3CCCCC3)nc2n1C1CCCC1 Show InChI InChI=1S/C31H42N8O2/c1-36(2)30(41)26-19-23-20-33-31(35-29(23)39(26)24-10-6-7-11-24)34-27-13-12-25(21-32-27)37-14-16-38(17-15-37)28(40)18-22-8-4-3-5-9-22/h12-13,19-22,24H,3-11,14-18H2,1-2H3,(H,32,33,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148258 (US8962630, 68) Show SMILES CC(C)CCCN1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C29H42N8O/c1-21(2)8-7-13-35-14-16-36(17-15-35)24-11-12-26(30-20-24)32-29-31-19-22-18-25(28(38)34(3)4)37(27(22)33-29)23-9-5-6-10-23/h11-12,18-21,23H,5-10,13-17H2,1-4H3,(H,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148217 (US8962630, 25) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC(F)(F)F)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C25H31F3N8O/c1-33(2)23(37)20-13-17-14-30-24(32-22(17)36(20)18-5-3-4-6-18)31-21-8-7-19(15-29-21)35-11-9-34(10-12-35)16-25(26,27)28/h7-8,13-15,18H,3-6,9-12,16H2,1-2H3,(H,29,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148201 (US8962630, 10) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC(N)=O)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C25H33N9O2/c1-31(2)24(36)20-13-17-14-28-25(30-23(17)34(20)18-5-3-4-6-18)29-22-8-7-19(15-27-22)33-11-9-32(10-12-33)16-21(26)35/h7-8,13-15,18H,3-6,9-12,16H2,1-2H3,(H2,26,35)(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148274 (US8962630, 84) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC#N)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C25H31N9O/c1-31(2)24(35)21-15-18-16-28-25(30-23(18)34(21)19-5-3-4-6-19)29-22-8-7-20(17-27-22)33-13-11-32(10-9-26)12-14-33/h7-8,15-17,19H,3-6,10-14H2,1-2H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148200 (US8962630, 9) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CCC#N)CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C26H33N9O/c1-32(2)25(36)22-16-19-17-29-26(31-24(19)35(22)20-6-3-4-7-20)30-23-9-8-21(18-28-23)34-14-12-33(13-15-34)11-5-10-27/h8-9,16-18,20H,3-7,11-15H2,1-2H3,(H,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148198 (US8962630, 7) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC3)C(C)=O)nc2n1C1CCCC1 Show InChI InChI=1S/C25H32N8O2/c1-17(34)31-10-12-32(13-11-31)20-8-9-22(26-16-20)28-25-27-15-18-14-21(24(35)30(2)3)33(23(18)29-25)19-6-4-5-7-19/h8-9,14-16,19H,4-7,10-13H2,1-3H3,(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148219 (US8962630, 27) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)C3CC3)nc2n1C1CCCC1 Show InChI InChI=1S/C27H34N8O2/c1-32(2)26(37)22-15-19-16-29-27(31-24(19)35(22)20-5-3-4-6-20)30-23-10-9-21(17-28-23)33-11-13-34(14-12-33)25(36)18-7-8-18/h9-10,15-18,20H,3-8,11-14H2,1-2H3,(H,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148215 (US8962630, 23) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)C3CCCCC3)nc2n1C1CCCC1 Show InChI InChI=1S/C30H40N8O2/c1-35(2)29(40)25-18-22-19-32-30(34-27(22)38(25)23-10-6-7-11-23)33-26-13-12-24(20-31-26)36-14-16-37(17-15-36)28(39)21-8-4-3-5-9-21/h12-13,18-21,23H,3-11,14-17H2,1-2H3,(H,31,32,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 205 total )  |  Next  |  Last  >>

Jump to: