Compile Data Set for Download or QSAR

Found 139 hits Enz. Inhib. hit(s) with all data for entry = 6934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM51439 (BDBM160336 | US9040714, 116 | US9693992, 116) Show SMILES Cc1c(-c2ccc(cc2)C(=O)NCCN2CCOCC2)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C24H24N2O6/c1-15-18-6-7-20(28)19(14-27)22(18)32-24(30)21(15)16-2-4-17(5-3-16)23(29)25-8-9-26-10-12-31-13-11-26/h2-7,14,28H,8-13H2,1H3,(H,25,29)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160334 (US9040714, 1 | US9693992, 1) Show SMILES Cc1c(Br)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C11H7BrO4/c1-5-6-2-3-8(14)7(4-13)10(6)16-11(15)9(5)12/h2-4,14H,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160335 (US9040714, 2 | US9693992, 2) Show SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1c(C)c2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C23H22N2O5/c1-14-17-7-8-19(27)18(13-26)21(17)30-23(29)20(14)15-3-5-16(6-4-15)22(28)25-11-9-24(2)10-12-25/h3-8,13,27H,9-12H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM51439 (BDBM160336 | US9040714, 116 | US9693992, 116) Show SMILES Cc1c(-c2ccc(cc2)C(=O)NCCN2CCOCC2)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C24H24N2O6/c1-15-18-6-7-20(28)19(14-27)22(18)32-24(30)21(15)16-2-4-17(5-3-16)23(29)25-8-9-26-10-12-31-13-11-26/h2-7,14,28H,8-13H2,1H3,(H,25,29)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160337 (US9040714, 4 | US9693992, 4) Show SMILES CCN(CC)CCc1c(C)c2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C17H21NO4/c1-4-18(5-2)9-8-13-11(3)12-6-7-15(20)14(10-19)16(12)22-17(13)21/h6-7,10,20H,4-5,8-9H2,1-3H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160338 (US9040714, 5 | US9693992, 5) Show SMILES CC(C)c1cc(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C13H12O4/c1-7(2)9-5-12(16)17-13-8(9)3-4-11(15)10(13)6-14/h3-7,15H,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160339 (US9040714, 6 | US9693992, 6) Show SMILES COc1cc2c(C)c(Br)c(=O)oc2c(C=O)c1O Show InChI InChI=1S/C12H9BrO5/c1-5-6-3-8(17-2)10(15)7(4-14)11(6)18-12(16)9(5)13/h3-4,15H,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160340 (US9040714, 7 | US9693992, 7) Show SMILES Oc1ccc2cc(-c3ccc(Br)cc3)c(=O)oc2c1C=O Show InChI InChI=1S/C16H9BrO4/c17-11-4-1-9(2-5-11)12-7-10-3-6-14(19)13(8-18)15(10)21-16(12)20/h1-8,19H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160343 (US9040714, 10 | US9693992, 10) Show SMILES CN1CCN(CC1)C(=O)c1cccc(c1)-c1c(C)c2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C23H22N2O5/c1-14-17-6-7-19(27)18(13-26)21(17)30-23(29)20(14)15-4-3-5-16(12-15)22(28)25-10-8-24(2)9-11-25/h3-7,12-13,27H,8-11H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160344 (US9040714, 11 | US9693992, 11) Show SMILES Cc1c(-c2cccc(c2)C(=O)NCCN2CCOCC2)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C24H24N2O6/c1-15-18-5-6-20(28)19(14-27)22(18)32-24(30)21(15)16-3-2-4-17(13-16)23(29)25-7-8-26-9-11-31-12-10-26/h2-6,13-14,28H,7-12H2,1H3,(H,25,29)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160345 (US9040714, 12 | US9693992, 12) Show SMILES Cc1c(-c2ccc(cc2)C(=O)N2CCOCC2)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C22H19NO6/c1-13-16-6-7-18(25)17(12-24)20(16)29-22(27)19(13)14-2-4-15(5-3-14)21(26)23-8-10-28-11-9-23/h2-7,12,25H,8-11H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160346 (US9040714, 13 | US9693992, 13) Show SMILES Cc1c(-c2cccc(c2)C(=O)N2CCOCC2)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C22H19NO6/c1-13-16-5-6-18(25)17(12-24)20(16)29-22(27)19(13)14-3-2-4-15(11-14)21(26)23-7-9-28-10-8-23/h2-6,11-12,25H,7-10H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160347 (US9040714, 14 | US9693992, 14) Show SMILES CN1CCN(CC1)c1ccc(cn1)-c1c(C)c2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C21H21N3O4/c1-13-15-4-5-17(26)16(12-25)20(15)28-21(27)19(13)14-3-6-18(22-11-14)24-9-7-23(2)8-10-24/h3-6,11-12,26H,7-10H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160348 (US9040714, 16 | US9693992, 16) Show SMILES Cc1c(Cc2ccccc2)c(=O)oc2c(C=O)c(O)c(O)cc12 Show InChI InChI=1S/C18H14O5/c1-10-12-8-15(20)16(21)14(9-19)17(12)23-18(22)13(10)7-11-5-3-2-4-6-11/h2-6,8-9,20-21H,7H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160349 (US9040714, 17 | US9693992, 17) Show SMILES CN(C)C(=O)c1ccc(cc1)-c1c(C)c2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C20H17NO5/c1-11-14-8-9-16(23)15(10-22)18(14)26-20(25)17(11)12-4-6-13(7-5-12)19(24)21(2)3/h4-10,23H,1-3H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160353 (US9040714, 21 | US9693992, 21) Show SMILES Cc1c(-c2cccc(c2)C(=O)N2CCCC2)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C22H19NO5/c1-13-16-7-8-18(25)17(12-24)20(16)28-22(27)19(13)14-5-4-6-15(11-14)21(26)23-9-2-3-10-23/h4-8,11-12,25H,2-3,9-10H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160354 (US9040714, 22 | US9693992, 22) Show SMILES Cc1cc(=O)oc2c(C=O)c(O)c(Cl)cc12 Show InChI InChI=1S/C11H7ClO4/c1-5-2-9(14)16-11-6(5)3-8(12)10(15)7(11)4-13/h2-4,15H,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160356 (US9040714, 24 | US9693992, 24) Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1c(C)c2cc(F)c(O)c(C=O)c2oc1=O Show InChI InChI=1S/C22H21FN2O4/c1-13-16-11-18(23)20(27)17(12-26)21(16)29-22(28)19(13)14-3-5-15(6-4-14)25-9-7-24(2)8-10-25/h3-6,11-12,27H,7-10H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160357 (US9040714, 25 | US9693992, 25) Show SMILES COc1cc2c(C)c(-c3ccc(cc3)N3CCN(C)CC3)c(=O)oc2c(C=O)c1O Show InChI InChI=1S/C23H24N2O5/c1-14-17-12-19(29-3)21(27)18(13-26)22(17)30-23(28)20(14)15-4-6-16(7-5-15)25-10-8-24(2)9-11-25/h4-7,12-13,27H,8-11H2,1-3H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160359 (US9040714, 27 | US9693992, 27) Show SMILES Cc1nc(sc1C(=O)N1CCOCC1)-c1cc2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C19H16N2O6S/c1-10-16(18(24)21-4-6-26-7-5-21)28-17(20-10)12-8-11-2-3-14(23)13(9-22)15(11)27-19(12)25/h2-3,8-9,23H,4-7H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160367 (US9040714, 35 | US9693992, 35) Show SMILES Cc1nc(sc1C(=O)NC1CCNCC1)N1CCc2c(C1)ccc(O)c2C=O Show InChI InChI=1S/C20H24N4O3S/c1-12-18(19(27)23-14-4-7-21-8-5-14)28-20(22-12)24-9-6-15-13(10-24)2-3-17(26)16(15)11-25/h2-3,11,14,21,26H,4-10H2,1H3,(H,23,27)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160369 (US9040714, 37 | US9693992, 37) Show SMILES Cc1nc(sc1C(=O)NCCN1CCOCC1)N1CCc2c(C1)ccc(O)c2C=O Show InChI InChI=1S/C21H26N4O4S/c1-14-19(20(28)22-5-7-24-8-10-29-11-9-24)30-21(23-14)25-6-4-16-15(12-25)2-3-18(27)17(16)13-26/h2-3,13,27H,4-12H2,1H3,(H,22,28)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160370 (US9040714, 38 | US9693992, 38) Show SMILES CN1CCN(CC1)c1ncc(s1)C(=O)N1CCc2c(C1)ccc(O)c2C=O Show InChI InChI=1S/C19H22N4O3S/c1-21-6-8-22(9-7-21)19-20-10-17(27-19)18(26)23-5-4-14-13(11-23)2-3-16(25)15(14)12-24/h2-3,10,12,25H,4-9,11H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160371 (US9040714, 39 | US9693992, 39) Show SMILES CCc1cc2c(occ(-c3nc(C)cs3)c2=O)c(C=O)c1O Show InChI InChI=1S/C16H13NO4S/c1-3-9-4-10-14(20)12(16-17-8(2)7-22-16)6-21-15(10)11(5-18)13(9)19/h4-7,19H,3H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160378 (US9040714, 46 | US9693992, 46) Show SMILES Oc1ccc2nc(ccc2c1C=O)-c1cccc(c1)C(=O)NCCN1CCOCC1 Show InChI InChI=1S/C23H23N3O4/c27-15-19-18-4-5-20(25-21(18)6-7-22(19)28)16-2-1-3-17(14-16)23(29)24-8-9-26-10-12-30-13-11-26/h1-7,14-15,28H,8-13H2,(H,24,29)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160379 (US9040714, 47 | US9693992, 47) Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc2c(C=O)c(O)ccc2n1 Show InChI InChI=1S/C23H22N2O3/c1-15-10-12-25(13-11-15)23(28)17-4-2-16(3-5-17)20-7-6-18-19(14-26)22(27)9-8-21(18)24-20/h2-9,14-15,27H,10-13H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160380 (US9040714, 48 | US9693992, 48) Show SMILES Oc1ccc2nc(ccc2c1C=O)-c1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C21H18N2O3/c24-13-17-16-7-8-18(22-19(16)9-10-20(17)25)14-3-5-15(6-4-14)21(26)23-11-1-2-12-23/h3-10,13,25H,1-2,11-12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM65645 (BDBM160381 | US9693992, 49) Show SMILES Oc1ccc2nc(ccc2c1C=O)-c1cccc(c1)C(=O)N1CCCC1 Show InChI InChI=1S/C21H18N2O3/c24-13-17-16-6-7-18(22-19(16)8-9-20(17)25)14-4-3-5-15(12-14)21(26)23-10-1-2-11-23/h3-9,12-13,25H,1-2,10-11H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160382 (US9040714, 50 | US9693992, 50) Show SMILES Oc1ccc2nc(ccc2c1C=O)N1CCC(C1)NC(=O)CN1CCOCC1 Show InChI InChI=1S/C20H24N4O4/c25-13-16-15-1-4-19(22-17(15)2-3-18(16)26)24-6-5-14(11-24)21-20(27)12-23-7-9-28-10-8-23/h1-4,13-14,26H,5-12H2,(H,21,27)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160383 (US9040714, 51 | US9693992, 51) Show SMILES CC(=O)NC1CCN(C1)c1ccc2c(C=O)c(O)ccc2n1 Show InChI InChI=1S/C16H17N3O3/c1-10(21)17-11-6-7-19(8-11)16-5-2-12-13(9-20)15(22)4-3-14(12)18-16/h2-5,9,11,22H,6-8H2,1H3,(H,17,21)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160384 (US9040714, 52 | US9693992, 52) Show SMILES CN1CCN(CC1)C(=O)c1cccc(c1)-c1nc2ccc(O)c(C=O)c2s1 Show InChI InChI=1S/C20H19N3O3S/c1-22-7-9-23(10-8-22)20(26)14-4-2-3-13(11-14)19-21-16-5-6-17(25)15(12-24)18(16)27-19/h2-6,11-12,25H,7-10H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160385 (US9040714, 53 | US9693992, 53) Show SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(O)c(C=O)c2s1 Show InChI InChI=1S/C20H19N3O3S/c1-22-8-10-23(11-9-22)20(26)14-4-2-13(3-5-14)19-21-16-6-7-17(25)15(12-24)18(16)27-19/h2-7,12,25H,8-11H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160386 (US9040714, 54 | US9693992, 54) Show SMILES CN1CCN(CC1)C1CCN(C1)c1nc2ccc(O)c(C=O)c2s1 Show InChI InChI=1S/C17H22N4O2S/c1-19-6-8-20(9-7-19)12-4-5-21(10-12)17-18-14-2-3-15(23)13(11-22)16(14)24-17/h2-3,11-12,23H,4-10H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160387 (US9040714, 55 | US9693992, 55) Show SMILES CC(C)N1CCN(CC1)c1nc2ccc(O)c(C=O)c2s1 Show InChI InChI=1S/C15H19N3O2S/c1-10(2)17-5-7-18(8-6-17)15-16-12-3-4-13(20)11(9-19)14(12)21-15/h3-4,9-10,20H,5-8H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160388 (US9040714, 56 | US9693992, 56) Show SMILES CN1CCN(CC1)C(=O)c1ccc(s1)-c1nc2ccc(O)c(C=O)c2s1 Show InChI InChI=1S/C18H17N3O3S2/c1-20-6-8-21(9-7-20)18(24)15-5-4-14(25-15)17-19-12-2-3-13(23)11(10-22)16(12)26-17/h2-5,10,23H,6-9H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160389 (US9040714, 57 | US9693992, 57) Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(O)c(C=O)c2s1 Show InChI InChI=1S/C21H20N2O3S/c1-13-8-10-23(11-9-13)21(26)15-4-2-14(3-5-15)20-22-17-6-7-18(25)16(12-24)19(17)27-20/h2-7,12-13,25H,8-11H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160392 (US9040714, 60 | US9693992, 60) Show SMILES Oc1ccc2nc([nH]c2c1C=O)-c1ccc(cc1)C(=O)NCCN1CCOCC1 Show InChI InChI=1S/C21H22N4O4/c26-13-16-18(27)6-5-17-19(16)24-20(23-17)14-1-3-15(4-2-14)21(28)22-7-8-25-9-11-29-12-10-25/h1-6,13,27H,7-12H2,(H,22,28)(H,23,24)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160393 (US9040714, 61 | US9693992, 61) Show SMILES Oc1ccc2nc([nH]c2c1C=O)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C19H17N3O4/c23-11-14-16(24)6-5-15-17(14)21-18(20-15)12-1-3-13(4-2-12)19(25)22-7-9-26-10-8-22/h1-6,11,24H,7-10H2,(H,20,21)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160394 (US9040714, 62 | US9693992, 62) Show SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(O)c(C=O)c2[nH]1 Show InChI InChI=1S/C20H20N4O3/c1-23-8-10-24(11-9-23)20(27)14-4-2-13(3-5-14)19-21-16-6-7-17(26)15(12-25)18(16)22-19/h2-7,12,26H,8-11H2,1H3,(H,21,22)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160395 (US9040714, 63 | US9693992, 63) Show SMILES OC(=O)CSc1nc2ccc(O)c(C=O)c2[nH]1 Show InChI InChI=1S/C10H8N2O4S/c13-3-5-7(14)2-1-6-9(5)12-10(11-6)17-4-8(15)16/h1-3,14H,4H2,(H,11,12)(H,15,16)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160396 (US9040714, 64 | US9693992, 64) Show SMILES OC(=O)c1cccc(c1)-c1nc2ccc(O)c(C=O)c2[nH]1 Show InChI InChI=1S/C15H10N2O4/c18-7-10-12(19)5-4-11-13(10)17-14(16-11)8-2-1-3-9(6-8)15(20)21/h1-7,19H,(H,16,17)(H,20,21)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160397 (US9040714, 65) Show SMILES COC(=O)c1cccc(c1)-c1nc2ccc(O)c(C=O)c2[nH]1 |$;;;;;;;;;;;;;;;;;;;;;HN$| Show InChI InChI=1S/C16H12N2O4/c1-22-16(21)10-4-2-3-9(7-10)15-17-12-5-6-13(20)11(8-19)14(12)18-15/h2-8,20H,1H3,(H,17,18)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160399 (US9040714, 68 | US9693992, 68) Show SMILES CCOC(=O)c1sc(nc1C)-c1cc2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C17H13NO6S/c1-3-23-17(22)14-8(2)18-15(25-14)10-6-9-4-5-12(20)11(7-19)13(9)24-16(10)21/h4-7,20H,3H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160400 (US9040714, 69 | US9693992, 69) Show SMILES Cc1c(CCC(=O)N2CCOCC2)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C18H19NO6/c1-11-12-2-4-15(21)14(10-20)17(12)25-18(23)13(11)3-5-16(22)19-6-8-24-9-7-19/h2,4,10,21H,3,5-9H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160401 (US9040714, 70 | US9693992, 70) Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C=O)c(O)ccc12 Show InChI InChI=1S/C13H10O6/c1-6-7-2-3-10(15)9(5-14)12(7)19-13(18)8(6)4-11(16)17/h2-3,5,15H,4H2,1H3,(H,16,17)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160402 (US9040714, 106 | US9693992, 106) Show SMILES CCOC(=O)c1cnc(s1)-c1cc2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C16H11NO6S/c1-2-22-16(21)12-6-17-14(24-12)9-5-8-3-4-11(19)10(7-18)13(8)23-15(9)20/h3-7,19H,2H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160403 (US9040714, 107 | US9693992, 107) Show SMILES CN1CCN(CC1)C(=O)c1cnc(s1)-c1cc2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C19H17N3O5S/c1-21-4-6-22(7-5-21)18(25)15-9-20-17(28-15)12-8-11-2-3-14(24)13(10-23)16(11)27-19(12)26/h2-3,8-10,24H,4-7H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160404 (US9040714, 108 | US9693992, 108) Show SMILES CN1CCN(CC1)C(=O)c1sc(nc1C)-c1cc2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C20H19N3O5S/c1-11-17(19(26)23-7-5-22(2)6-8-23)29-18(21-11)13-9-12-3-4-15(25)14(10-24)16(12)28-20(13)27/h3-4,9-10,25H,5-8H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160405 (US9040714, 109 | US9693992, 109) Show SMILES Cc1nc(sc1C(=O)NCCN1CCOCC1)-c1cc2ccc(O)c(C=O)c2oc1=O Show InChI InChI=1S/C21H21N3O6S/c1-12-18(19(27)22-4-5-24-6-8-29-9-7-24)31-20(23-12)14-10-13-2-3-16(26)15(11-25)17(13)30-21(14)28/h2-3,10-11,26H,4-9H2,1H3,(H,22,27)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM160407 (US9040714, 111 | US9693992, 111) Show SMILES COc1cc2c(C)c(-c3ccc(cc3)C(=O)N3CCN(C)CC3)c(=O)oc2c(C=O)c1O Show InChI InChI=1S/C24H24N2O6/c1-14-17-12-19(31-3)21(28)18(13-27)22(17)32-24(30)20(14)15-4-6-16(7-5-15)23(29)26-10-8-25(2)9-11-26/h4-7,12-13,28H,8-11H2,1-3H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
MannKind Corporation US Patent					Assay Description A fusion protein comprising glutathione S transferase (GST) and human IRE-1alpha (GST-IRE-1alpha) obtained from a 500 ml baculovirus-infected insect ...				US Patent US9040714 (2015) BindingDB Entry DOI: 10.7270/Q2S75F3S
					More data for this Ligand-Target Pair

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