Compile Data Set for Download or QSAR

Found 368 hits Enz. Inhib. hit(s) with all data for entry = 7031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167858 (US9073922, 355) Show SMILES Fc1cccc(CNc2nc(c(F)cc2F)-c2ccnc3[nH]c(cc23)C2CCNCC2)c1 Show InChI InChI=1S/C24H22F3N5/c25-16-3-1-2-14(10-16)13-30-24-20(27)12-19(26)22(32-24)17-6-9-29-23-18(17)11-21(31-23)15-4-7-28-8-5-15/h1-3,6,9-12,15,28H,4-5,7-8,13H2,(H,29,31)(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167859 (US9073922, 356) Show SMILES CNC(=O)N1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cncc(OCc2cccc(F)c2)n1 |c:7| Show InChI InChI=1S/C25H23FN6O2/c1-27-25(33)32-9-6-17(7-10-32)21-12-20-19(5-8-29-24(20)31-21)22-13-28-14-23(30-22)34-15-16-3-2-4-18(26)11-16/h2-6,8,11-14H,7,9-10,15H2,1H3,(H,27,33)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167860 (US9073922, 357) Show SMILES OCC(=O)N1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cncc(OCc2cccc(F)c2)n1 |c:7| Show InChI InChI=1S/C25H22FN5O3/c26-18-3-1-2-16(10-18)15-34-23-13-27-12-22(29-23)19-4-7-28-25-20(19)11-21(30-25)17-5-8-31(9-6-17)24(33)14-32/h1-5,7,10-13,32H,6,8-9,14-15H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167699 (US9073922, 186 | US9796708, Example 186) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1=CCN(CC(O)CO)CC1 |t:21| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167819 (US9073922, 315) Show SMILES C(Nc1cncc(n1)-c1ccnc2[nH]c(cc12)C1CCNCC1)c1ccccc1 Show InChI InChI=1S/C23H24N6/c1-2-4-16(5-3-1)13-27-22-15-25-14-21(28-22)18-8-11-26-23-19(18)12-20(29-23)17-6-9-24-10-7-17/h1-5,8,11-12,14-15,17,24H,6-7,9-10,13H2,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167821 (US9073922, 317) Show SMILES Fc1cc(F)cc(CNc2cncc(n2)-c2ccnc3[nH]c(cc23)C2CCNCC2)c1 Show InChI InChI=1S/C23H22F2N6/c24-16-7-14(8-17(25)9-16)11-29-22-13-27-12-21(30-22)18-3-6-28-23-19(18)10-20(31-23)15-1-4-26-5-2-15/h3,6-10,12-13,15,26H,1-2,4-5,11H2,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167863 (US9073922, 360) Show SMILES OCC(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1nc(NCc2cccc(F)c2)c(F)cc1F Show InChI InChI=1S/C26H24F3N5O2/c27-17-3-1-2-15(10-17)13-31-26-21(29)12-20(28)24(33-26)18-4-7-30-25-19(18)11-22(32-25)16-5-8-34(9-6-16)23(36)14-35/h1-4,7,10-12,16,35H,5-6,8-9,13-14H2,(H,30,32)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167850 (US9073922, 347) Show SMILES Fc1cccc(COc2cncc(n2)-c2ccnc3[nH]c(cc23)C2=CCNCC2)c1 |t:26| Show InChI InChI=1S/C23H20FN5O/c24-17-3-1-2-15(10-17)14-30-22-13-26-12-21(28-22)18-6-9-27-23-19(18)11-20(29-23)16-4-7-25-8-5-16/h1-4,6,9-13,25H,5,7-8,14H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167703 (US9073922, 190 | US9796708, Example 190) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cc(NCc2ccc(cc2)S(C)(=O)=O)ccc1F Show InChI InChI=1S/C27H29FN4O2S/c1-32-13-10-19(11-14-32)26-16-24-22(9-12-29-27(24)31-26)23-15-20(5-8-25(23)28)30-17-18-3-6-21(7-4-18)35(2,33)34/h3-9,12,15-16,19,30H,10-11,13-14,17H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167716 (US9073922, 203 | US9796708, Example 203) Show SMILES Fc1cccc(CNc2ccc(Cl)c(n2)-c2ccnc3[nH]c(cc23)C2CCCNC2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167857 (US9073922, 354) Show SMILES CS(=O)(=O)N1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cncc(OCc2cccc(F)c2)n1 |c:7| Show InChI InChI=1S/C24H22FN5O3S/c1-34(31,32)30-9-6-17(7-10-30)21-12-20-19(5-8-27-24(20)29-21)22-13-26-14-23(28-22)33-15-16-3-2-4-18(25)11-16/h2-6,8,11-14H,7,9-10,15H2,1H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167812 (US9073922, 308) Show SMILES NC1CCCC(C1)c1cc2c(ccnc2[nH]1)-c1cccc(NCc2cccc(F)c2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167825 (US9073922, 321) Show SMILES Fc1ccc(CNc2cncc(n2)-c2ccnc3[nH]c(cc23)C2CCNCC2)cc1F Show InChI InChI=1S/C23H22F2N6/c24-18-2-1-14(9-19(18)25)11-29-22-13-27-12-21(30-22)16-5-8-28-23-17(16)10-20(31-23)15-3-6-26-7-4-15/h1-2,5,8-10,12-13,15,26H,3-4,6-7,11H2,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167848 (US9073922, 345) Show SMILES Fc1cccc(CNc2cncc(n2)-c2ccnc3[nH]c(cc23)C2=CCNCC2)c1 |t:26| Show InChI InChI=1S/C23H21FN6/c24-17-3-1-2-15(10-17)12-28-22-14-26-13-21(29-22)18-6-9-27-23-19(18)11-20(30-23)16-4-7-25-8-5-16/h1-4,6,9-11,13-14,25H,5,7-8,12H2,(H,27,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167856 (US9073922, 353) Show SMILES OCC(=O)N1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2cccc(F)c2)n1 |c:7| Show InChI InChI=1S/C25H23FN6O2/c26-18-3-1-2-16(10-18)12-29-23-14-27-13-22(30-23)19-4-7-28-25-20(19)11-21(31-25)17-5-8-32(9-6-17)24(34)15-33/h1-5,7,10-11,13-14,33H,6,8-9,12,15H2,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167553 (US9073922, 37 | US9796708, Example 37) Show SMILES Fc1cncc(CNc2ccc(Cl)c(n2)-c2ccnc3[nH]c(cc23)C2CCNCC2)c1 Show InChI InChI=1S/C23H22ClFN6/c24-19-1-2-21(29-12-14-9-16(25)13-27-11-14)31-22(19)17-5-8-28-23-18(17)10-20(30-23)15-3-6-26-7-4-15/h1-2,5,8-11,13,15,26H,3-4,6-7,12H2,(H,28,30)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167602 (US9073922, 87 | US9796708, Example 87) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1=CCNCC1 |t:21| Show InChI InChI=1S/C19H18FN3O/c1-24-18-3-2-13(20)10-15(18)14-6-9-22-19-16(14)11-17(23-19)12-4-7-21-8-5-12/h2-4,6,9-11,21H,5,7-8H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167822 (US9073922, 318) Show SMILES Fc1cccc(CNc2cncc(n2)-c2ccnc3[nH]c(cc23)C2CCNCC2)c1 Show InChI InChI=1S/C23H23FN6/c24-17-3-1-2-15(10-17)12-28-22-14-26-13-21(29-22)18-6-9-27-23-19(18)11-20(30-23)16-4-7-25-8-5-16/h1-3,6,9-11,13-14,16,25H,4-5,7-8,12H2,(H,27,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167830 (US9073922, 326) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2ccccc2)n1 Show InChI InChI=1S/C24H26N6/c1-30-11-8-18(9-12-30)21-13-20-19(7-10-26-24(20)29-21)22-15-25-16-23(28-22)27-14-17-5-3-2-4-6-17/h2-7,10,13,15-16,18H,8-9,11-12,14H2,1H3,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167862 (US9073922, 359) Show SMILES CNC(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1nc(NCc2cccc(F)c2)c(F)cc1F Show InChI InChI=1S/C26H25F3N6O/c1-30-26(36)35-9-6-16(7-10-35)22-12-19-18(5-8-31-24(19)33-22)23-20(28)13-21(29)25(34-23)32-14-15-3-2-4-17(27)11-15/h2-5,8,11-13,16H,6-7,9-10,14H2,1H3,(H,30,36)(H,31,33)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167533 (US9073922, 17 | US9796708, Example 17) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1CCNCC1 Show InChI InChI=1S/C19H20FN3O/c1-24-18-3-2-13(20)10-15(18)14-6-9-22-19-16(14)11-17(23-19)12-4-7-21-8-5-12/h2-3,6,9-12,21H,4-5,7-8H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167719 (US9073922, 206 | US9796708, Example 206) Show SMILES Fc1ccc(NCc2ccccc2)cc1-c1ccnc2[nH]c(cc12)C1CCCNC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167827 (US9073922, 323) Show SMILES OCC(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2cccc(F)c2)n1 Show InChI InChI=1S/C25H25FN6O2/c26-18-3-1-2-16(10-18)12-29-23-14-27-13-22(30-23)19-4-7-28-25-20(19)11-21(31-25)17-5-8-32(9-6-17)24(34)15-33/h1-4,7,10-11,13-14,17,33H,5-6,8-9,12,15H2,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167841 (US9073922, 337) Show SMILES OCC(O)CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(OCc2cccc(F)c2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167865 (US9073922, 362) Show SMILES CNC(=O)C1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2ccccc2)n1 |c:7| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167538 (US9073922, 22 | US9796708, Example 22) Show SMILES COc1cc(F)c(F)cc1-c1ccnc2[nH]c(cc12)C1CCNCC1 Show InChI InChI=1S/C19H19F2N3O/c1-25-18-10-16(21)15(20)8-13(18)12-4-7-23-19-14(12)9-17(24-19)11-2-5-22-6-3-11/h4,7-11,22H,2-3,5-6H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167616 (US9073922, 102 | US9796708, Example 102) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cccc(NCc2c(F)cccc2F)n1 Show InChI InChI=1S/C25H25F2N5/c1-32-12-9-16(10-13-32)23-14-18-17(8-11-28-25(18)31-23)22-6-3-7-24(30-22)29-15-19-20(26)4-2-5-21(19)27/h2-8,11,14,16H,9-10,12-13,15H2,1H3,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167659 (US9073922, 146 | US9796708, Example 146) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1CNC1 Show InChI InChI=1S/C17H16FN3O/c1-22-16-3-2-11(18)6-13(16)12-4-5-20-17-14(12)7-15(21-17)10-8-19-9-10/h2-7,10,19H,8-9H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167835 (US9073922, 331) Show SMILES Fc1cccc(COc2cncc(n2)-c2ccnc3[nH]c(cc23)C2CCNCC2)c1 Show InChI InChI=1S/C23H22FN5O/c24-17-3-1-2-15(10-17)14-30-22-13-26-12-21(28-22)18-6-9-27-23-19(18)11-20(29-23)16-4-7-25-8-5-16/h1-3,6,9-13,16,25H,4-5,7-8,14H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167619 (US9073922, 105 | US9796708, Example 105) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cccc(NCc2ccc3OCOc3c2)n1 Show InChI InChI=1S/C26H27N5O2/c1-31-11-8-18(9-12-31)22-14-20-19(7-10-27-26(20)30-22)21-3-2-4-25(29-21)28-15-17-5-6-23-24(13-17)33-16-32-23/h2-7,10,13-14,18H,8-9,11-12,15-16H2,1H3,(H,27,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167838 (US9073922, 334) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(OCc2cccc(F)c2)n1 Show InChI InChI=1S/C24H24FN5O/c1-30-9-6-17(7-10-30)21-12-20-19(5-8-27-24(20)29-21)22-13-26-14-23(28-22)31-15-16-3-2-4-18(25)11-16/h2-5,8,11-14,17H,6-7,9-10,15H2,1H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167567 (US9073922, 52 | US9796708, Example 52) Show SMILES Clc1cnc(NCc2ccccc2)cc1-c1ccnc2[nH]c(cc12)C1CCNCC1 Show InChI InChI=1S/C24H24ClN5/c25-21-15-29-23(28-14-16-4-2-1-3-5-16)13-19(21)18-8-11-27-24-20(18)12-22(30-24)17-6-9-26-10-7-17/h1-5,8,11-13,15,17,26H,6-7,9-10,14H2,(H,27,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167611 (US9073922, 97 | US9796708, Example 97) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cccc(NCc2cccc(Cl)c2)n1 Show InChI InChI=1S/C25H26ClN5/c1-31-12-9-18(10-13-31)23-15-21-20(8-11-27-25(21)30-23)22-6-3-7-24(29-22)28-16-17-4-2-5-19(26)14-17/h2-8,11,14-15,18H,9-10,12-13,16H2,1H3,(H,27,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167626 (US9073922, 112 | US9796708, Example 112) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1CCN(Cc2cccnc2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167642 (US9073922, 129 | US9796708, Example 129) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1CCCN(CCCN)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167836 (US9073922, 332) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2cccc(F)c2)n1 Show InChI InChI=1S/C24H25FN6/c1-31-9-6-17(7-10-31)21-12-20-19(5-8-27-24(20)30-21)22-14-26-15-23(29-22)28-13-16-3-2-4-18(25)11-16/h2-5,8,11-12,14-15,17H,6-7,9-10,13H2,1H3,(H,27,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167842 (US9073922, 338) Show SMILES CCOC(=O)NS(=O)(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2cccc(F)c2)n1 Show InChI InChI=1S/C26H28FN7O4S/c1-2-38-26(35)33-39(36,37)34-10-7-18(8-11-34)22-13-21-20(6-9-29-25(21)32-22)23-15-28-16-24(31-23)30-14-17-4-3-5-19(27)12-17/h3-6,9,12-13,15-16,18H,2,7-8,10-11,14H2,1H3,(H,29,32)(H,30,31)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167849 (US9073922, 346) Show SMILES OCC(O)CN1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2cccc(F)c2)n1 |c:8| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167520 (US9073922, 4 | US9796708, Example 4) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)[C@@H]1CCCNC1 Show InChI InChI=1S/C19H20FN3O/c1-24-18-5-4-13(20)9-15(18)14-6-8-22-19-16(14)10-17(23-19)12-3-2-7-21-11-12/h4-6,8-10,12,21H,2-3,7,11H2,1H3,(H,22,23)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167549 (US9073922, 33 | US9796708, Example 33) Show SMILES Fc1cccc(CNc2ccc(Cl)c(n2)-c2ccnc3[nH]c(cc23)C2CCNCC2)c1 Show InChI InChI=1S/C24H23ClFN5/c25-20-4-5-22(29-14-15-2-1-3-17(26)12-15)31-23(20)18-8-11-28-24-19(18)13-21(30-24)16-6-9-27-10-7-16/h1-5,8,11-13,16,27H,6-7,9-10,14H2,(H,28,30)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167571 (US9073922, 56 | US9796708, Example 56) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cccc(NCc2ccccc2)n1 Show InChI InChI=1S/C25H27N5/c1-30-14-11-19(12-15-30)23-16-21-20(10-13-26-25(21)29-23)22-8-5-9-24(28-22)27-17-18-6-3-2-4-7-18/h2-10,13,16,19H,11-12,14-15,17H2,1H3,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167572 (US9073922, 57 | US9796708, Example 57) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1nc(NCc2cccc(F)c2)ccc1Cl Show InChI InChI=1S/C25H25ClFN5/c1-32-11-8-17(9-12-32)22-14-20-19(7-10-28-25(20)30-22)24-21(26)5-6-23(31-24)29-15-16-3-2-4-18(27)13-16/h2-7,10,13-14,17H,8-9,11-12,15H2,1H3,(H,28,30)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167577 (US9073922, 62 | US9796708, Example 62) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)[C@@H]1CCNC1 Show InChI InChI=1S/C18H18FN3O/c1-23-17-3-2-12(19)8-14(17)13-5-7-21-18-15(13)9-16(22-18)11-4-6-20-10-11/h2-3,5,7-9,11,20H,4,6,10H2,1H3,(H,21,22)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167669 (US9073922, 156 | US9796708, Example 156) Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cccc(NCc2cc[nH]n2)n1 Show InChI InChI=1S/C22H25N7/c1-29-11-7-15(8-12-29)20-13-18-17(6-9-23-22(18)27-20)19-3-2-4-21(26-19)24-14-16-5-10-25-28-16/h2-6,9-10,13,15H,7-8,11-12,14H2,1H3,(H,23,27)(H,24,26)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167811 (US9073922, 307) Show SMILES Fc1cccc(CNc2cc(c(Cl)cn2)-c2ccnc3[nH]c(cc23)C2CCNCC2)c1 Show InChI InChI=1S/C24H23ClFN5/c25-21-14-30-23(29-13-15-2-1-3-17(26)10-15)12-19(21)18-6-9-28-24-20(18)11-22(31-24)16-4-7-27-8-5-16/h1-3,6,9-12,14,16,27H,4-5,7-8,13H2,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167818 (US9073922, 314) Show SMILES CS(=O)(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2ccccc2)n1 Show InChI InChI=1S/C24H26N6O2S/c1-33(31,32)30-11-8-18(9-12-30)21-13-20-19(7-10-26-24(20)29-21)22-15-25-16-23(28-22)27-14-17-5-3-2-4-6-17/h2-7,10,13,15-16,18H,8-9,11-12,14H2,1H3,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167833 (US9073922, 329) Show SMILES CCN(C([O-])=O)S(=O)(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2ccccc2)n1 Show InChI InChI=1S/C26H29N7O4S/c1-2-33(26(34)35)38(36,37)32-12-9-19(10-13-32)22-14-21-20(8-11-28-25(21)31-22)23-16-27-17-24(30-23)29-15-18-6-4-3-5-7-18/h3-8,11,14,16-17,19H,2,9-10,12-13,15H2,1H3,(H,28,31)(H,29,30)(H,34,35)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167839 (US9073922, 335) Show SMILES C(Nc1cncc(n1)-c1ccnc2[nH]c(cc12)C1=CCNCC1)c1ccccc1 |t:20| Show InChI InChI=1S/C23H22N6/c1-2-4-16(5-3-1)13-27-22-15-25-14-21(28-22)18-8-11-26-23-19(18)12-20(29-23)17-6-9-24-10-7-17/h1-6,8,11-12,14-15,24H,7,9-10,13H2,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167517 (US9073922, 1 | US9796708, Example 1) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1CCCNC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167544 (US9073922, 28 | US9796708, Example 28) Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1CCN(C)CC1 Show InChI InChI=1S/C20H22FN3O/c1-24-9-6-13(7-10-24)18-12-17-15(5-8-22-20(17)23-18)16-11-14(21)3-4-19(16)25-2/h3-5,8,11-13H,6-7,9-10H2,1-2H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair

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