Compile Data Set for Download or QSAR

Found 49 hits Enz. Inhib. hit(s) with all data for entry = 7560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443712 (CHEMBL3093861 | US9238658, 33) Show SMILES OC1CCc2nc(NC(=O)N3CCC(CC3)N3CCc4ccc(F)cc34)sc2C1 Show InChI InChI=1S/C21H25FN4O2S/c22-14-2-1-13-5-10-26(18(13)11-14)15-6-8-25(9-7-15)21(28)24-20-23-17-4-3-16(27)12-19(17)29-20/h1-2,11,15-16,27H,3-10,12H2,(H,23,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443716 (CHEMBL3093874 | US9238658, 50) Show SMILES OCCc1cnc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)s1 Show InChI InChI=1S/C19H23FN4O2S/c20-14-2-1-13-3-9-24(17(13)11-14)15-4-7-23(8-5-15)19(26)22-18-21-12-16(27-18)6-10-25/h1-2,11-12,15,25H,3-10H2,(H,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202530 (US9238658, 55) Show SMILES OCCc1cnc(NC(=O)N2CCC(CC2)c2noc3ccc(F)cc23)s1 Show InChI InChI=1S/C18H19FN4O3S/c19-12-1-2-15-14(9-12)16(22-26-15)11-3-6-23(7-4-11)18(25)21-17-20-10-13(27-17)5-8-24/h1-2,9-11,24H,3-8H2,(H,20,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443710 (CHEMBL3093863 | US9238658, 37) Show SMILES Fc1ccc2CCN(C3CCN(CC3)C(=O)Nc3cc4C(=O)NCCn4n3)c2c1 Show InChI InChI=1S/C20H23FN6O2/c21-14-2-1-13-3-9-26(16(13)11-14)15-4-7-25(8-5-15)20(29)23-18-12-17-19(28)22-6-10-27(17)24-18/h1-2,11-12,15H,3-10H2,(H,22,28)(H,23,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202523 (US9238658, 47) Show SMILES Fc1ccc2CCN(C3CCN(CC3)C(=O)Nc3ccc4COC(=O)c4c3)c2c1 Show InChI InChI=1S/C22H22FN3O3/c23-16-3-1-14-5-10-26(20(14)11-16)18-6-8-25(9-7-18)22(28)24-17-4-2-15-13-29-21(27)19(15)12-17/h1-4,11-12,18H,5-10,13H2,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443712 (CHEMBL3093861 | US9238658, 33) Show SMILES OC1CCc2nc(NC(=O)N3CCC(CC3)N3CCc4ccc(F)cc34)sc2C1 Show InChI InChI=1S/C21H25FN4O2S/c22-14-2-1-13-5-10-26(18(13)11-14)15-6-8-25(9-7-15)21(28)24-20-23-17-4-3-16(27)12-19(17)29-20/h1-2,11,15-16,27H,3-10,12H2,(H,23,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443717 (CHEMBL3093873 | US9238658, 29) Show SMILES OCCc1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C19H23FN4O2S/c20-14-2-1-13-3-9-24(17(13)11-14)16-4-7-23(8-5-16)19(26)22-18-21-15(6-10-25)12-27-18/h1-2,11-12,16,25H,3-10H2,(H,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202505 (US9238658, 16) Show SMILES NC(=O)c1cccc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)c1 Show InChI InChI=1S/C21H23FN4O2/c22-16-5-4-14-6-11-26(19(14)13-16)18-7-9-25(10-8-18)21(28)24-17-3-1-2-15(12-17)20(23)27/h1-5,12-13,18H,6-11H2,(H2,23,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443714 (CHEMBL3093876 | US9238658, 15) Show SMILES NC(=O)c1cnc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)s1 Show InChI InChI=1S/C18H20FN5O2S/c19-12-2-1-11-3-8-24(14(11)9-12)13-4-6-23(7-5-13)18(26)22-17-21-10-15(27-17)16(20)25/h1-2,9-10,13H,3-8H2,(H2,20,25)(H,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443710 (CHEMBL3093863 | US9238658, 37) Show SMILES Fc1ccc2CCN(C3CCN(CC3)C(=O)Nc3cc4C(=O)NCCn4n3)c2c1 Show InChI InChI=1S/C20H23FN6O2/c21-14-2-1-13-3-9-26(16(13)11-14)15-4-7-25(8-5-15)20(29)23-18-12-17-19(28)22-6-10-27(17)24-18/h1-2,11-12,15H,3-10H2,(H,22,28)(H,23,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443722 (CHEMBL3093868 | US9238658, 20) Show SMILES Cc1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C18H21FN4OS/c1-12-11-25-17(20-12)21-18(24)22-7-5-15(6-8-22)23-9-4-13-2-3-14(19)10-16(13)23/h2-3,10-11,15H,4-9H2,1H3,(H,20,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202529 (US9238658, 54) Show SMILES OCCc1csc(NC(=O)N2CCC(CC2)c2noc3ccc(F)cc23)n1 Show InChI InChI=1S/C18H19FN4O3S/c19-12-1-2-15-14(9-12)16(22-26-15)11-3-6-23(7-4-11)18(25)21-17-20-13(5-8-24)10-27-17/h1-2,9-11,24H,3-8H2,(H,20,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443713 (CHEMBL3093860 | US9238658, 36) Show SMILES Fc1ccc2CCN(C3CCN(CC3)C(=O)Nc3nc4CCNCc4s3)c2c1 Show InChI InChI=1S/C20H24FN5OS/c21-14-2-1-13-4-10-26(17(13)11-14)15-5-8-25(9-6-15)20(27)24-19-23-16-3-7-22-12-18(16)28-19/h1-2,11,15,22H,3-10,12H2,(H,23,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202533 (US9238658, 60) Show SMILES OC1CCc2nc(NC(=O)N3CCC(CC3)c3noc4ccc(F)cc34)sc2C1 Show InChI InChI=1S/C20H21FN4O3S/c21-12-1-4-16-14(9-12)18(24-28-16)11-5-7-25(8-6-11)20(27)23-19-22-15-3-2-13(26)10-17(15)29-19/h1,4,9,11,13,26H,2-3,5-8,10H2,(H,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443719 (CHEMBL3093871 | US9238658, 25) Show SMILES OCc1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C18H21FN4O2S/c19-13-2-1-12-3-8-23(16(12)9-13)15-4-6-22(7-5-15)18(25)21-17-20-14(10-24)11-26-17/h1-2,9,11,15,24H,3-8,10H2,(H,20,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202516 (US9238658, 39) Show SMILES NC(=O)c1cccc(NC(=O)N2CCC(CC2)n2ncc3c(F)cccc23)c1 Show InChI InChI=1S/C20H20FN5O2/c21-17-5-2-6-18-16(17)12-23-26(18)15-7-9-25(10-8-15)20(28)24-14-4-1-3-13(11-14)19(22)27/h1-6,11-12,15H,7-10H2,(H2,22,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443720 (CHEMBL3093870 | US9238658, 21) Show SMILES Cc1cnc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)s1 Show InChI InChI=1S/C18H21FN4OS/c1-12-11-20-17(25-12)21-18(24)22-7-5-15(6-8-22)23-9-4-13-2-3-14(19)10-16(13)23/h2-3,10-11,15H,4-9H2,1H3,(H,20,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202534 (US9238658, 63) Show SMILES Fc1ccc2onc(C3CCN(CC3)C(=O)Nc3nc4CCOCc4s3)c2c1 Show InChI InChI=1S/C19H19FN4O3S/c20-12-1-2-15-13(9-12)17(23-27-15)11-3-6-24(7-4-11)19(25)22-18-21-14-5-8-26-10-16(14)28-18/h1-2,9,11H,3-8,10H2,(H,21,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202516 (US9238658, 39) Show SMILES NC(=O)c1cccc(NC(=O)N2CCC(CC2)n2ncc3c(F)cccc23)c1 Show InChI InChI=1S/C20H20FN5O2/c21-17-5-2-6-18-16(17)12-23-26(18)15-7-9-25(10-8-15)20(28)24-14-4-1-3-13(11-14)19(22)27/h1-6,11-12,15H,7-10H2,(H2,22,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443718 (CHEMBL3093872 | US9238658, 24) Show SMILES OCc1cnc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)s1 Show InChI InChI=1S/C18H21FN4O2S/c19-13-2-1-12-3-8-23(16(12)9-13)14-4-6-22(7-5-14)18(25)21-17-20-10-15(11-24)26-17/h1-2,9-10,14,24H,3-8,11H2,(H,20,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443730 (CHEMBL3093878 | US9238658, 19) Show SMILES CNC(=O)c1cnc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)s1 Show InChI InChI=1S/C19H22FN5O2S/c1-21-17(26)16-11-22-18(28-16)23-19(27)24-7-5-14(6-8-24)25-9-4-12-2-3-13(20)10-15(12)25/h2-3,10-11,14H,4-9H2,1H3,(H,21,26)(H,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443711 (CHEMBL3093862 | US9238658, 35) Show SMILES OCC(=O)N1CCc2nc(NC(=O)N3CCC(CC3)N3CCc4ccc(F)cc34)sc2C1 Show InChI InChI=1S/C22H26FN5O3S/c23-15-2-1-14-3-10-28(18(14)11-15)16-4-7-26(8-5-16)22(31)25-21-24-17-6-9-27(20(30)13-29)12-19(17)32-21/h1-2,11,16,29H,3-10,12-13H2,(H,24,25,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443721 (CHEMBL3093869 | US9238658, 6) Show SMILES Cc1csc(NC(=O)N2CCC(CC2)c2noc3ccc(F)cc23)n1 Show InChI InChI=1S/C17H17FN4O2S/c1-10-9-25-16(19-10)20-17(23)22-6-4-11(5-7-22)15-13-8-12(18)2-3-14(13)24-21-15/h2-3,8-9,11H,4-7H2,1H3,(H,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443724 (CHEMBL3093866 | US9238658, 3) Show SMILES Cc1csc(NC(=O)N2CCC(CC2)N2CCc3ccccc23)n1 Show InChI InChI=1S/C18H22N4OS/c1-13-12-24-17(19-13)20-18(23)21-9-7-15(8-10-21)22-11-6-14-4-2-3-5-16(14)22/h2-5,12,15H,6-11H2,1H3,(H,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443726 (CHEMBL3093883 | US9238658, 12) Show SMILES CNC(=O)c1cccc(NC(=O)N2CCC(CC2)N2CCc3ccccc23)c1 Show InChI InChI=1S/C22H26N4O2/c1-23-21(27)17-6-4-7-18(15-17)24-22(28)25-12-10-19(11-13-25)26-14-9-16-5-2-3-8-20(16)26/h2-8,15,19H,9-14H2,1H3,(H,23,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443724 (CHEMBL3093866 | US9238658, 3) Show SMILES Cc1csc(NC(=O)N2CCC(CC2)N2CCc3ccccc23)n1 Show InChI InChI=1S/C18H22N4OS/c1-13-12-24-17(19-13)20-18(23)21-9-7-15(8-10-21)22-11-6-14-4-2-3-5-16(14)22/h2-5,12,15H,6-11H2,1H3,(H,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443727 (CHEMBL3093882 | US9238658, 2) Show SMILES CNC(=O)c1cccc(NC(=O)N2CCC(CC2)n2ccc3ccccc23)c1 Show InChI InChI=1S/C22H24N4O2/c1-23-21(27)17-6-4-7-18(15-17)24-22(28)25-12-10-19(11-13-25)26-14-9-16-5-2-3-8-20(16)26/h2-9,14-15,19H,10-13H2,1H3,(H,23,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443728 (CHEMBL3093880 | US9238658, 61) Show SMILES Fc1ccc2CCN(C3CCN(CC3)C(=O)Nc3nc4CCOCc4s3)c2c1 Show InChI InChI=1S/C20H23FN4O2S/c21-14-2-1-13-3-9-25(17(13)11-14)15-4-7-24(8-5-15)20(26)23-19-22-16-6-10-27-12-18(16)28-19/h1-2,11,15H,3-10,12H2,(H,22,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202506 (US9238658, 17) Show SMILES NC(=O)c1cccc(NC(=O)N2CCC(CC2)c2noc3ccc(F)cc23)c1 Show InChI InChI=1S/C20H19FN4O3/c21-14-4-5-17-16(11-14)18(24-28-17)12-6-8-25(9-7-12)20(27)23-15-3-1-2-13(10-15)19(22)26/h1-5,10-12H,6-9H2,(H2,22,26)(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202509 (US9238658, 27) Show SMILES CCOC(=O)Cc1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C21H25FN4O3S/c1-2-29-19(27)12-16-13-30-20(23-16)24-21(28)25-8-6-17(7-9-25)26-10-5-14-3-4-15(22)11-18(14)26/h3-4,11,13,17H,2,5-10,12H2,1H3,(H,23,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202504 (US9238658, 14) Show SMILES Cc1cnc(NC(=O)N2CCC(CC2)c2noc3ccc(F)cc23)s1 Show InChI InChI=1S/C17H17FN4O2S/c1-10-9-19-16(25-10)20-17(23)22-6-4-11(5-7-22)15-13-8-12(18)2-3-14(13)24-21-15/h2-3,8-9,11H,4-7H2,1H3,(H,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202519 (US9238658, 43) Show SMILES OCc1cccc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)c1 Show InChI InChI=1S/C21H24FN3O2/c22-17-5-4-16-6-11-25(20(16)13-17)19-7-9-24(10-8-19)21(27)23-18-3-1-2-15(12-18)14-26/h1-5,12-13,19,26H,6-11,14H2,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	322	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443729 (CHEMBL3093879 | US9238658, 62) Show SMILES Fc1ccc2CCN(C3CCN(CC3)C(=O)Nc3nc4CCCCc4s3)c2c1 Show InChI InChI=1S/C21H25FN4OS/c22-15-6-5-14-7-12-26(18(14)13-15)16-8-10-25(11-9-16)21(27)24-20-23-17-3-1-2-4-19(17)28-20/h5-6,13,16H,1-4,7-12H2,(H,23,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202507 (US9238658, 18) Show SMILES COC(=O)c1cnc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)s1 Show InChI InChI=1S/C19H21FN4O3S/c1-27-17(25)16-11-21-18(28-16)22-19(26)23-7-5-14(6-8-23)24-9-4-12-2-3-13(20)10-15(12)24/h2-3,10-11,14H,4-9H2,1H3,(H,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	363	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202498 (US9238658, 5) Show SMILES CNC(=O)c1cccc(NC(=O)N2CCC(CC2)c2noc3ccc(F)cc23)c1 Show InChI InChI=1S/C21H21FN4O3/c1-23-20(27)14-3-2-4-16(11-14)24-21(28)26-9-7-13(8-10-26)19-17-12-15(22)5-6-18(17)29-25-19/h2-6,11-13H,7-10H2,1H3,(H,23,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	413	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202501 (US9238658, 9) Show SMILES CCCc1nc2ccc(NC(=O)N3CCC(CC3)c3noc4ccc(F)cc34)cc2s1 Show InChI InChI=1S/C23H23FN4O2S/c1-2-3-21-26-18-6-5-16(13-20(18)31-21)25-23(29)28-10-8-14(9-11-28)22-17-12-15(24)4-7-19(17)30-27-22/h4-7,12-14H,2-3,8-11H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	444	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443723 (CHEMBL3093867 | US9238658, 13) Show SMILES Cc1csc(NC(=O)N2CCC(CC2)N2CCCc3ccccc23)n1 Show InChI InChI=1S/C19H24N4OS/c1-14-13-25-18(20-14)21-19(24)22-11-8-16(9-12-22)23-10-4-6-15-5-2-3-7-17(15)23/h2-3,5,7,13,16H,4,6,8-12H2,1H3,(H,20,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	491	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443725 (CHEMBL3093865 | US9238658, 4) Show SMILES Cc1csc(NC(=O)N2CCC(CC2)n2ccc3ccccc23)n1 Show InChI InChI=1S/C18H20N4OS/c1-13-12-24-17(19-13)20-18(23)21-9-7-15(8-10-21)22-11-6-14-4-2-3-5-16(14)22/h2-6,11-12,15H,7-10H2,1H3,(H,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	502	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202517 (US9238658, 41) Show SMILES CCOC(=O)c1cccc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)c1 Show InChI InChI=1S/C23H26FN3O3/c1-2-30-22(28)17-4-3-5-19(14-17)25-23(29)26-11-9-20(10-12-26)27-13-8-16-6-7-18(24)15-21(16)27/h3-7,14-15,20H,2,8-13H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	534	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443725 (CHEMBL3093865 | US9238658, 4) Show SMILES Cc1csc(NC(=O)N2CCC(CC2)n2ccc3ccccc23)n1 Show InChI InChI=1S/C18H20N4OS/c1-13-12-24-17(19-13)20-18(23)21-9-7-15(8-10-21)22-11-6-14-4-2-3-5-16(14)22/h2-6,11-12,15H,7-10H2,1H3,(H,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	573	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202526 (US9238658, 51) Show SMILES CCOC(=O)Cc1csc(NC(=O)N2CCC(CC2)c2noc3ccc(F)cc23)n1 Show InChI InChI=1S/C20H21FN4O4S/c1-2-28-17(26)10-14-11-30-19(22-14)23-20(27)25-7-5-12(6-8-25)18-15-9-13(21)3-4-16(15)29-24-18/h3-4,9,11-12H,2,5-8,10H2,1H3,(H,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	579	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50443715 (CHEMBL3093875 | US9238658, 26) Show SMILES NC(=O)c1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C18H20FN5O2S/c19-12-2-1-11-3-8-24(15(11)9-12)13-4-6-23(7-5-13)18(26)22-17-21-14(10-27-17)16(20)25/h1-2,9-10,13H,3-8H2,(H2,20,25)(H,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	682	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202515 (US9238658, 38) Show SMILES OCCN1CCc2nc(NC(=O)N3CCC(CC3)N3CCc4ccc(F)cc34)sc2C1 Show InChI InChI=1S/C22H28FN5O2S/c23-16-2-1-15-3-10-28(19(15)13-16)17-4-8-27(9-5-17)22(30)25-21-24-18-6-7-26(11-12-29)14-20(18)31-21/h1-2,13,17,29H,3-12,14H2,(H,24,25,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202511 (US9238658, 30) Show SMILES NC(=O)Cc1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C19H22FN5O2S/c20-13-2-1-12-3-8-25(16(12)9-13)15-4-6-24(7-5-15)19(27)23-18-22-14(11-28-18)10-17(21)26/h1-2,9,11,15H,3-8,10H2,(H2,21,26)(H,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	845	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202524 (US9238658, 48) Show SMILES NC(=O)c1cc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)ccc1CO Show InChI InChI=1S/C22H25FN4O3/c23-16-3-1-14-5-10-27(20(14)11-16)18-6-8-26(9-7-18)22(30)25-17-4-2-15(13-28)19(12-17)21(24)29/h1-4,11-12,18,28H,5-10,13H2,(H2,24,29)(H,25,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	909	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202495 (US9238658, 23) Show SMILES CNC(=O)c1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C19H22FN5O2S/c1-21-17(26)15-11-28-18(22-15)23-19(27)24-7-5-14(6-8-24)25-9-4-12-2-3-13(20)10-16(12)25/h2-3,10-11,14H,4-9H2,1H3,(H,21,26)(H,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202508 (US9238658, 22) Show SMILES CCOC(=O)c1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C20H23FN4O3S/c1-2-28-18(26)16-12-29-19(22-16)23-20(27)24-8-6-15(7-9-24)25-10-5-13-3-4-14(21)11-17(13)25/h3-4,11-12,15H,2,5-10H2,1H3,(H,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202510 (US9238658, 28) Show SMILES CNC(=O)Cc1csc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)n1 Show InChI InChI=1S/C20H24FN5O2S/c1-22-18(27)11-15-12-29-19(23-15)24-20(28)25-7-5-16(6-8-25)26-9-4-13-2-3-14(21)10-17(13)26/h2-3,10,12,16H,4-9,11H2,1H3,(H,22,27)(H,23,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM202499 (US9238658, 7) Show SMILES CCCc1nc2ccc(NC(=O)N3CCC(CC3)c3noc4ccc(F)cc34)cc2o1 Show InChI InChI=1S/C23H23FN4O3/c1-2-3-21-26-18-6-5-16(13-20(18)30-21)25-23(29)28-10-8-14(9-11-28)22-17-12-15(24)4-7-19(17)31-27-22/h4-7,12-14H,2-3,8-11H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...				US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D
					More data for this Ligand-Target Pair