Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM50180302![]() (8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | n/a | n/a | 30.8 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406720![]() (US10336757, Compound PU-DZ18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 107 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM50180306![]() (8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISO...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 122 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM50180301![]() (2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | n/a | n/a | 60.7 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406700![]() (US10336757, Compound PU-DZ10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 193 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406701![]() (US10336757, Compound PU-HT70) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 147 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406702![]() (US10336757, Compound PU-HT78) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 9.56E+3 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406703![]() (US10336757, Compound PU-HT133) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 813 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406704![]() (US10336757, Compound PU-BSI12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 39.4 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406705![]() (US10336757, Compound PU-BSI6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 60.8 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406706![]() (US10336757, Compound PU-BSI11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406707![]() (US10336757, Compound PU-BSI7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 44.5 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406708![]() (US10336757, Compound PU-BSI14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 42.8 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406709![]() (US10336757, Compound PU-BSI15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 68.2 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406710![]() (US10336757, Compound PU-BSI4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 95.3 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406711![]() (US10336757, Compound PU-BSI10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 105 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406712![]() (US10336757, Compound PU-BSI3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 199 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406713![]() (US10336757, Compound PU-BSI16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 202 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406714![]() (US10336757, Compound PU-DZ12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 219 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406715![]() (US10336757, Compound PU-DZ13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 19.6 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406716![]() (US10336757, Compound PU-DZ14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 23.5 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406717![]() (US10336757, Compound PU-DZ16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 35.6 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406718![]() (US10336757, Compound PU-DZ15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 166 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406719![]() (US10336757, Compound PU-DZ17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 92.3 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human)) | BDBM406697![]() (US10336757, Compound PU-HT65) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 213 | n/a | n/a | n/a | n/a |
Sloan-Kettering Institute for Cancer Research US Patent | Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl... | US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6 | |||||||||||
More data for this Ligand-Target Pair |