Compile Data Set for Download or QSAR

Found 455 hits Enz. Inhib. hit(s) with all data for entry = 8927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ADAMTS5 (Rattus norvegicus (Rat))	BDBM429695 (5-(3-(4-(3- fluorophenyl) piperidin-1-yl)- 2-methy...) Show SMILES C[C@@H](C[C@@]1(C)NC(=O)NC1=O)C(=O)N1CCC(CC1)c1cccc(F)c1 |r| Show InChI InChI=1S/C19H24FN3O3/c1-12(11-19(2)17(25)21-18(26)22-19)16(24)23-8-6-13(7-9-23)14-4-3-5-15(20)10-14/h3-5,10,12-13H,6-9,11H2,1-2H3,(H2,21,22,25,26)/t12-,19+/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by rnADAMTS-5 (1-564-6H).For the d...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429748 ((R)-5-(3-(4- (3,4-dichloro-5- methoxyphenyl) piper...) Show SMILES COc1cc(cc(Cl)c1Cl)C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C18H21Cl2N3O4/c1-27-14-9-11(8-12(19)16(14)20)10-4-6-23(7-5-10)15(24)3-2-13-17(25)22-18(26)21-13/h8-10,13H,2-7H2,1H3,(H2,21,22,25,26)/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429750 (5-(3-(4-(4,5- dichloro-2- methylphenyl) piperidin-...) Show SMILES Cc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H23Cl2N3O3/c1-11-9-14(20)15(21)10-13(11)12-4-7-24(8-5-12)16(25)3-6-19(2)17(26)22-18(27)23-19/h9-10,12H,3-8H2,1-2H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429751 (5-(3-(4-(4- fluoro-3,5- dimethoxyphenyl) piperidin...) Show SMILES COc1cc(cc(OC)c1F)C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C20H26FN3O5/c1-20(18(26)22-19(27)23-20)7-4-16(25)24-8-5-12(6-9-24)13-10-14(28-2)17(21)15(11-13)29-3/h10-12H,4-9H2,1-3H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429752 (5-(3-(4-(3- chloro-4- fluoro-5- methoxyphenyl) pip...) Show SMILES COc1cc(cc(Cl)c1F)C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H23ClFN3O4/c1-19(17(26)22-18(27)23-19)6-3-15(25)24-7-4-11(5-8-24)12-9-13(20)16(21)14(10-12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429758 ((5R)-5-[3-[4- (4-chloro-2- methoxy- phenyl)-1- pip...) Show SMILES COc1cc(Cl)ccc1C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H24ClN3O4/c1-19(17(25)21-18(26)22-19)8-5-16(24)23-9-6-12(7-10-23)14-4-3-13(20)11-15(14)27-2/h3-4,11-12H,5-10H2,1-2H3,(H2,21,22,25,26)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429759 ((5R)-5-[3-[4- (3-chloro-4- fluoro-5- methoxy- phen...) Show SMILES COc1cc(cc(Cl)c1F)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H23ClFN3O4/c1-19(17(26)22-18(27)23-19)6-3-15(25)24-7-4-11(5-8-24)12-9-13(20)16(21)14(10-12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429760 ((5R)-5-[3-[4- (4-fluoro-3,5- dimethoxy- phenyl)-1-...) Show SMILES COc1cc(cc(OC)c1F)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26FN3O5/c1-20(18(26)22-19(27)23-20)7-4-16(25)24-8-5-12(6-9-24)13-10-14(28-2)17(21)15(11-13)29-3/h10-12H,4-9H2,1-3H3,(H2,22,23,26,27)/t20-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429761 ((5R)-5-[3-[4- (4-fluoro-3,5- dimethoxy- phenyl)-1-...) Show SMILES COc1cc(cc(OC)c1F)C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C19H24FN3O5/c1-27-14-9-12(10-15(28-2)17(14)20)11-5-7-23(8-6-11)16(24)4-3-13-18(25)22-19(26)21-13/h9-11,13H,3-8H2,1-2H3,(H2,21,22,25,26)/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429763 ((5R)-5-[3-[4- (4-chloro-3- fluoro-5- methoxy- phen...) Show SMILES COc1cc(cc(F)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H23ClFN3O4/c1-19(17(26)22-18(27)23-19)6-3-15(25)24-7-4-11(5-8-24)12-9-13(21)16(20)14(10-12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429765 ((5R)-5-[3-[4- (4-chloro-3- methoxy- phenyl)-1- pip...) Show SMILES COc1cc(ccc1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H24ClN3O4/c1-19(17(25)21-18(26)22-19)8-5-16(24)23-9-6-12(7-10-23)13-3-4-14(20)15(11-13)27-2/h3-4,11-12H,5-10H2,1-2H3,(H2,21,22,25,26)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429767 ((5R)-5-[3-[4- (4-chloro-3- ethoxy-5- methoxy- phen...) Show SMILES CCOc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H28ClN3O5/c1-4-30-16-12-14(11-15(29-3)18(16)22)13-6-9-25(10-7-13)17(26)5-8-21(2)19(27)23-20(28)24-21/h11-13H,4-10H2,1-3H3,(H2,23,24,27,28)/t21-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429768 ((5R)-5-[3-[4- (4-chloro-3- ethoxy-5- methoxy- phen...) Show SMILES CCOc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26ClN3O5/c1-3-29-16-11-13(10-15(28-2)18(16)21)12-6-8-24(9-7-12)17(25)5-4-14-19(26)23-20(27)22-14/h10-12,14H,3-9H2,1-2H3,(H2,22,23,26,27)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429769 ((5R)-5-[3-[4- (4-chloro-2- methoxy-5- methyl- phen...) Show SMILES COc1cc(Cl)c(C)cc1C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26ClN3O4/c1-12-10-14(16(28-3)11-15(12)21)13-5-8-24(9-6-13)17(25)4-7-20(2)18(26)22-19(27)23-20/h10-11,13H,4-9H2,1-3H3,(H2,22,23,26,27)/t20-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429770 ((5R)-5-[3-[4- [4-chloro-3- (dimethylamino)- 5-meth...) Show SMILES COc1cc(cc(N(C)C)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H29ClN4O4/c1-21(19(28)23-20(29)24-21)8-5-17(27)26-9-6-13(7-10-26)14-11-15(25(2)3)18(22)16(12-14)30-4/h11-13H,5-10H2,1-4H3,(H2,23,24,28,29)/t21-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429795 (5-[3-[4-(4,5- dichloro-2- methoxy- phenyl)-1- pipe...) Show SMILES COc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CCC1(NC(=O)NC1=O)c1cccc(C)n1 Show InChI InChI=1S/C24H26Cl2N4O4/c1-14-4-3-5-20(27-14)24(22(32)28-23(33)29-24)9-6-21(31)30-10-7-15(8-11-30)16-12-17(25)18(26)13-19(16)34-2/h3-5,12-13,15H,6-11H2,1-2H3,(H2,28,29,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429771 ((5R)-5-[3-[4- (4-chloro-3,5- dimethyl- phenyl)-1- ...) Show SMILES Cc1cc(cc(C)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26ClN3O3/c1-12-10-15(11-13(2)17(12)21)14-5-8-24(9-6-14)16(25)4-7-20(3)18(26)22-19(27)23-20/h10-11,14H,4-9H2,1-3H3,(H2,22,23,26,27)/t20-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429797 ((5R)-5-[3-[4- (4-chloro-3- methyl- phenyl)-1- pipe...) Show SMILES Cc1cc(ccc1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H24ClN3O3/c1-12-11-14(3-4-15(12)20)13-6-9-23(10-7-13)16(24)5-8-19(2)17(25)21-18(26)22-19/h3-4,11,13H,5-10H2,1-2H3,(H2,21,22,25,26)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429772 ((5R)-5-[3-[4- (4,5-dichloro- 2-methoxy- phenyl)-1-...) Show SMILES COc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H23Cl2N3O4/c1-19(17(26)22-18(27)23-19)6-3-16(25)24-7-4-11(5-8-24)12-9-13(20)14(21)10-15(12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429773 (5-[3-[4-(4- chloro-2- methoxy- phenyl)-1- piperidy...) Show SMILES COc1cc(Cl)ccc1C1CCN(CC1)C(=O)[C@@H](C)C[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26ClN3O4/c1-12(11-20(2)18(26)22-19(27)23-20)17(25)24-8-6-13(7-9-24)15-5-4-14(21)10-16(15)28-3/h4-5,10,12-13H,6-9,11H2,1-3H3,(H2,22,23,26,27)/t12-,20+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429774 ((5R)-5-[3-[4- (4-chloro-3- methoxy-5- methyl- phen...) Show SMILES COc1cc(cc(C)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26ClN3O4/c1-12-10-14(11-15(28-3)17(12)21)13-5-8-24(9-6-13)16(25)4-7-20(2)18(26)22-19(27)23-20/h10-11,13H,4-9H2,1-3H3,(H2,22,23,26,27)/t20-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429776 ((5R)-5-[3-[4- (4-chloro-5- fluoro-2- methoxy- phen...) Show SMILES COc1cc(Cl)c(F)cc1C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H23ClFN3O4/c1-19(17(26)22-18(27)23-19)6-3-16(25)24-7-4-11(5-8-24)12-9-14(21)13(20)10-15(12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429778 (5-[3-[4-(4- chloro-3- fluoro-5- methoxy- phenyl)-1...) Show SMILES COc1cc(cc(F)c1Cl)C1CCN(CC1)C(=O)[C@@H](C)C[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H25ClFN3O4/c1-11(10-20(2)18(27)23-19(28)24-20)17(26)25-6-4-12(5-7-25)13-8-14(22)16(21)15(9-13)29-3/h8-9,11-12H,4-7,10H2,1-3H3,(H2,23,24,27,28)/t11-,20+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429779 (5-[3-[4-(4- chloro-3- fluoro-5- methoxy- phenyl)-1...) Show SMILES COC[C@]1(C[C@H](C)C(=O)N2CCC(CC2)c2cc(F)c(Cl)c(OC)c2)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H27ClFN3O5/c1-12(10-21(11-30-2)19(28)24-20(29)25-21)18(27)26-6-4-13(5-7-26)14-8-15(23)17(22)16(9-14)31-3/h8-9,12-13H,4-7,10-11H2,1-3H3,(H2,24,25,28,29)/t12-,21-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429780 (5-[3-[4-(4- chloro-3-ethyl- 5-methoxy- phenyl)-1- ...) Show SMILES CCc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)[C@@H](C)C[C@@]1(COC)NC(=O)NC1=O |r| Show InChI InChI=1S/C23H32ClN3O5/c1-5-15-10-17(11-18(32-4)19(15)24)16-6-8-27(9-7-16)20(28)14(2)12-23(13-31-3)21(29)25-22(30)26-23/h10-11,14,16H,5-9,12-13H2,1-4H3,(H2,25,26,29,30)/t14-,23-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429781 ((5R)-5-[3-[4- (4-chloro-3- ethyl-5-methoxy- phenyl...) Show SMILES CCc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H28ClN3O4/c1-4-13-11-15(12-16(29-3)18(13)22)14-6-9-25(10-7-14)17(26)5-8-21(2)19(27)23-20(28)24-21/h11-12,14H,4-10H2,1-3H3,(H2,23,24,27,28)/t21-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429782 ((5R)-5-[3-[4- (4-chloro-3- ethyl-5- methoxy- pheny...) Show SMILES CCc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(COC)NC(=O)NC1=O |r| Show InChI InChI=1S/C22H30ClN3O5/c1-4-14-11-16(12-17(31-3)19(14)23)15-6-9-26(10-7-15)18(27)5-8-22(13-30-2)20(28)24-21(29)25-22/h11-12,15H,4-10,13H2,1-3H3,(H2,24,25,28,29)/t22-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429783 (5-[3-[4-(5- chloro-4- fluoro-2- methoxy- phenyl)-1...) Show SMILES COC[C@]1(C[C@H](C)C(=O)N2CCC(CC2)c2cc(Cl)c(F)cc2OC)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H27ClFN3O5/c1-12(10-21(11-30-2)19(28)24-20(29)25-21)18(27)26-6-4-13(5-7-26)14-8-15(22)16(23)9-17(14)31-3/h8-9,12-13H,4-7,10-11H2,1-3H3,(H2,24,25,28,29)/t12-,21-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429784 (5-[3-[4-(4- chloro-2- methoxy- phenyl)-1- piperidy...) Show SMILES COC[C@]1(C[C@H](C)C(=O)N2CCC(CC2)c2ccc(Cl)cc2OC)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H28ClN3O5/c1-13(11-21(12-29-2)19(27)23-20(28)24-21)18(26)25-8-6-14(7-9-25)16-5-4-15(22)10-17(16)30-3/h4-5,10,13-14H,6-9,11-12H2,1-3H3,(H2,23,24,27,28)/t13-,21-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429785 (5-[3-[4-(4- chloro-5- fluoro-2- methoxy- phenyl)-1...) Show SMILES COC[C@]1(C[C@H](C)C(=O)N2CCC(CC2)c2cc(F)c(Cl)cc2OC)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H27ClFN3O5/c1-12(10-21(11-30-2)19(28)24-20(29)25-21)18(27)26-6-4-13(5-7-26)14-8-16(23)15(22)9-17(14)31-3/h8-9,12-13H,4-7,10-11H2,1-3H3,(H2,24,25,28,29)/t12-,21-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429773 (5-[3-[4-(4- chloro-2- methoxy- phenyl)-1- piperidy...) Show SMILES COc1cc(Cl)ccc1C1CCN(CC1)C(=O)[C@@H](C)C[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26ClN3O4/c1-12(11-20(2)18(26)22-19(27)23-20)17(25)24-8-6-13(7-9-24)15-5-4-14(21)10-16(15)28-3/h4-5,10,12-13H,6-9,11H2,1-3H3,(H2,22,23,26,27)/t12-,20+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429787 (5-[3-[4-(5- chloro-4- fluoro-2- methoxy- phenyl)-1...) Show SMILES COc1cc(F)c(Cl)cc1C1CCN(CC1)C(=O)[C@@H](C)C[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H25ClFN3O4/c1-11(10-20(2)18(27)23-19(28)24-20)17(26)25-6-4-12(5-7-25)13-8-14(21)15(22)9-16(13)29-3/h8-9,11-12H,4-7,10H2,1-3H3,(H2,23,24,27,28)/t11-,20+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429789 (5-[3-[4-(4- chloro-3- methoxy-5- methyl- phenyl)-1...) Show SMILES COc1cc(cc(C)c1Cl)C1CCN(CC1)C(=O)[C@@H](C)C[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H28ClN3O4/c1-12-9-15(10-16(29-4)17(12)22)14-5-7-25(8-6-14)18(26)13(2)11-21(3)19(27)23-20(28)24-21/h9-10,13-14H,5-8,11H2,1-4H3,(H2,23,24,27,28)/t13-,21+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429790 (5-[3-[4-(4- chloro-3- methoxy-5- methyl- phenyl)-1...) Show SMILES COC[C@]1(C[C@H](C)C(=O)N2CCC(CC2)c2cc(C)c(Cl)c(OC)c2)NC(=O)NC1=O |r| Show InChI InChI=1S/C22H30ClN3O5/c1-13-9-16(10-17(31-4)18(13)23)15-5-7-26(8-6-15)19(27)14(2)11-22(12-30-3)20(28)24-21(29)25-22/h9-10,14-15H,5-8,11-12H2,1-4H3,(H2,24,25,28,29)/t14-,22-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429791 ((5R)-5-[3-[4- (4-chloro-3- methoxy-5- methyl- phen...) Show SMILES COc1cc(cc(C)c1Cl)C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C19H24ClN3O4/c1-11-9-13(10-15(27-2)17(11)20)12-5-7-23(8-6-12)16(24)4-3-14-18(25)22-19(26)21-14/h9-10,12,14H,3-8H2,1-2H3,(H2,21,22,25,26)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human))	BDBM429779 (5-[3-[4-(4- chloro-3- fluoro-5- methoxy- phenyl)-1...) Show SMILES COC[C@]1(C[C@H](C)C(=O)N2CCC(CC2)c2cc(F)c(Cl)c(OC)c2)NC(=O)NC1=O |r| Show InChI InChI=1S/C21H27ClFN3O5/c1-12(10-21(11-30-2)19(28)24-20(29)25-21)18(27)26-6-4-13(5-7-26)14-8-15(23)17(22)16(9-14)31-3/h8-9,12-13H,4-7,10-11H2,1-3H3,(H2,24,25,28,29)/t12-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS-5.For the dose res...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429688 ((R)-5-(3-(4-(4- chloro-3,5- dimethoxy- phenyl)pipe...) Show SMILES COc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C19H24ClN3O5/c1-27-14-9-12(10-15(28-2)17(14)20)11-5-7-23(8-6-11)16(24)4-3-13-18(25)22-19(26)21-13/h9-11,13H,3-8H2,1-2H3,(H2,21,22,25,26)/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429689 (5-(3-(4-(4- chloro-3,5- dimethoxy- phenyl)piperidi...) Show SMILES COc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C20H26ClN3O5/c1-20(18(26)22-19(27)23-20)7-4-16(25)24-8-5-12(6-9-24)13-10-14(28-2)17(21)15(11-13)29-3/h10-12H,4-9H2,1-3H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429691 (5-(3-(4-(4- chlorophenyl) piperidin-1- yl)-2-methy...) Show SMILES C[C@@H](C[C@@]1(C)NC(=O)NC1=O)C(=O)N1CCC(CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H24ClN3O3/c1-12(11-19(2)17(25)21-18(26)22-19)16(24)23-9-7-14(8-10-23)13-3-5-15(20)6-4-13/h3-6,12,14H,7-11H2,1-2H3,(H2,21,22,25,26)/t12-,19+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429692 (5-(3-(4-(3,5- dichlorophenyl) piperidin-1- yl)-2-m...) Show SMILES C[C@@H](C[C@@]1(C)NC(=O)NC1=O)C(=O)N1CCC(CC1)c1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C19H23Cl2N3O3/c1-11(10-19(2)17(26)22-18(27)23-19)16(25)24-5-3-12(4-6-24)13-7-14(20)9-15(21)8-13/h7-9,11-12H,3-6,10H2,1-2H3,(H2,22,23,26,27)/t11-,19+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429715 (5-(3-(4-(4- chloro-3- methoxyl- phenyl)piperidin-1...) Show SMILES COc1cc(ccc1Cl)C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H24ClN3O4/c1-19(17(25)21-18(26)22-19)8-5-16(24)23-9-6-12(7-10-23)13-3-4-14(20)15(11-13)27-2/h3-4,11-12H,5-10H2,1-2H3,(H2,21,22,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429716 (5-(3-(4-(4- chloro-5- methoxy-2- methylphenyl) pip...) Show SMILES COc1cc(C2CCN(CC2)C(=O)CCC2(C)NC(=O)NC2=O)c(C)cc1Cl Show InChI InChI=1S/C20H26ClN3O4/c1-12-10-15(21)16(28-3)11-14(12)13-5-8-24(9-6-13)17(25)4-7-20(2)18(26)22-19(27)23-20/h10-11,13H,4-9H2,1-3H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429723 (5-(3-(4-(4- chloro-2- methoxyphenyl) piperidin-1- ...) Show SMILES COc1cc(Cl)ccc1C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H24ClN3O4/c1-19(17(25)21-18(26)22-19)8-5-16(24)23-9-6-12(7-10-23)14-4-3-13(20)11-15(14)27-2/h3-4,11-12H,5-10H2,1-2H3,(H2,21,22,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429724 (5-(3-(4-(3,4- difluoro-5- methoxyphenyl) piperidin...) Show SMILES COc1cc(cc(F)c1F)C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H23F2N3O4/c1-19(17(26)22-18(27)23-19)6-3-15(25)24-7-4-11(5-8-24)12-9-13(20)16(21)14(10-12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429725 ((R)-5-(3-(4-(4- chloro-3- fluoro-5- methoxyphenyl)...) Show SMILES COc1cc(cc(F)c1Cl)C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C18H21ClFN3O4/c1-27-14-9-11(8-12(20)16(14)19)10-4-6-23(7-5-10)15(24)3-2-13-17(25)22-18(26)21-13/h8-10,13H,2-7H2,1H3,(H2,21,22,25,26)/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429726 (5-(3-(4-(4- chloro-3- fluoro-5- methoxyphenyl) pip...) Show SMILES COc1cc(cc(F)c1Cl)C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H23ClFN3O4/c1-19(17(26)22-18(27)23-19)6-3-15(25)24-7-4-11(5-8-24)12-9-13(21)16(20)14(10-12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429740 ((R)-5-(3-(4- (4,5-dichloro- 2- methoxyphenyl) pipe...) Show SMILES COc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C18H21Cl2N3O4/c1-27-15-9-13(20)12(19)8-11(15)10-4-6-23(7-5-10)16(24)3-2-14-17(25)22-18(26)21-14/h8-10,14H,2-7H2,1H3,(H2,21,22,25,26)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429741 (5-(3-(4-(4,5- dichloro-2- methoxyphenyl) piperidin...) Show SMILES COc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H23Cl2N3O4/c1-19(17(26)22-18(27)23-19)6-3-16(25)24-7-4-11(5-8-24)12-9-13(20)14(21)10-15(12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429745 ((R)-5-(3-(4-(3- chloro-5- methoxyphenyl) piperidin...) Show SMILES COc1cc(Cl)cc(c1)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H24ClN3O4/c1-19(17(25)21-18(26)22-19)6-3-16(24)23-7-4-12(5-8-23)13-9-14(20)11-15(10-13)27-2/h9-12H,3-8H2,1-2H3,(H2,21,22,25,26)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429747 ((R)-5-(3-(4- (3,4-dichloro-5- methoxyphenyl) piper...) Show SMILES COc1cc(cc(Cl)c1Cl)C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C19H23Cl2N3O4/c1-19(17(26)22-18(27)23-19)6-3-15(25)24-7-4-11(5-8-24)12-9-13(20)16(21)14(10-12)28-2/h9-11H,3-8H2,1-2H3,(H2,22,23,26,27)/t19-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
					More data for this Ligand-Target Pair

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