Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6' and Ligand = 'BDBM429768'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429768 ((5R)-5-[3-[4- (4-chloro-3- ethoxy-5- methoxy- phen...) Show SMILES CCOc1cc(cc(OC)c1Cl)C1CCN(CC1)C(=O)CC[C@H]1NC(=O)NC1=O |r| Show InChI InChI=1S/C20H26ClN3O5/c1-3-29-16-11-13(10-15(28-2)18(16)21)12-6-8-24(9-7-12)17(25)5-4-14-19(26)23-20(27)22-14/h10-12,14H,3-9H2,1-2H3,(H2,22,23,26,27)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
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