Compile Data Set for Download or QSAR

Found 193 hits Enz. Inhib. hit(s) with all data for entry = 9743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485754 ((R)-3-(5-fluorothiophen-2- yl)-3-(isoquinolin-5-yl...) Show SMILES CNCC[C@@H](Oc1cccc2cnccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485784 ((S)-3-(3-Fluorothiophen-2-yl)-3-(isoquinolin-5-ylo...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-11-20-9-5-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485761 ((R)-N-methyl-3-((1- methylisoquinolin-5- yl)oxy)-3...) Show SMILES CNCC[C@@H](Oc1cccc2c(C)nccc12)c1cccs1 |r| Show InChI InChI=1S/C18H20N2OS/c1-13-14-5-3-6-16(15(14)8-11-20-13)21-17(9-10-19-2)18-7-4-12-22-18/h3-8,11-12,17,19H,9-10H2,1-2H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485780 ((S)-3-(5-Chlorothiophen-2-yl)-N-methyl-3-(quinolin...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccc(Cl)s1 |r| Show InChI InChI=1S/C17H17ClN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485764 ((R)-N-methyl-3-((1- methylisoquinolin-8- yl)oxy)-3...) Show SMILES CNCC[C@@H](Oc1cccc2ccnc(C)c12)c1cccs1 |r| Show InChI InChI=1S/C18H20N2OS/c1-13-18-14(8-11-20-13)5-3-6-16(18)21-15(9-10-19-2)17-7-4-12-22-17/h3-8,11-12,15,19H,9-10H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485768 ((R)-3-((2,4- dimethylquinolin-5- yl)oxy)-N-methyl-...) Show SMILES CNCC[C@@H](Oc1cccc2nc(C)cc(C)c12)c1cccs1 |r| Show InChI InChI=1S/C19H22N2OS/c1-13-12-14(2)21-15-6-4-7-17(19(13)15)22-16(9-10-20-3)18-8-5-11-23-18/h4-8,11-12,16,20H,9-10H2,1-3H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485744 (3-(5-fluorothiophen-2-yl)- N-methyl-3-(quinolin-5-...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485747 (3-(5-fluorothiophen-2-yl)- 3-(isoquinolin-5-yloxy)...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485707 (N-ethyl-3-(isoquinolin-5- yloxy)-3-(thiophen-2- yl...) Show SMILES CCNCCC(Oc1cccc2cnccc12)c1cccs1 Show InChI InChI=1S/C18H20N2OS/c1-2-19-11-9-17(18-7-4-12-22-18)21-16-6-3-5-14-13-20-10-8-15(14)16/h3-8,10,12-13,17,19H,2,9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485711 ((S)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-2- ...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-16(17-8-4-12-21-17)20-15-7-2-6-14-13(15)5-3-10-19-14/h2-8,10,12,16,18H,9,11H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485718 (5-(3-(methylamino)-1- (thiophen-2- yl)propoxy)isoq...) Show SMILES CNCCC(Oc1cccc2c(nccc12)C(N)=O)c1cccs1 Show InChI InChI=1S/C18H19N3O2S/c1-20-9-8-15(16-6-3-11-24-16)23-14-5-2-4-13-12(14)7-10-21-17(13)18(19)22/h2-7,10-11,15,20H,8-9H2,1H3,(H2,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485791 ((R)-5-(3-(ethylamino)-1- (thiophen-2- yl)propoxy)i...) Show SMILES CCNCC[C@@H](Oc1cccc2c(nccc12)C#N)c1cccs1 |r| Show InChI InChI=1S/C19H19N3OS/c1-2-21-10-9-18(19-7-4-12-24-19)23-17-6-3-5-14-15(17)8-11-22-16(14)13-20/h3-8,11-12,18,21H,2,9-10H2,1H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485692 (US10941138, Example 1) Show SMILES CNCCC(Oc1cccc2cccnc12)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-14(16-8-4-12-21-16)20-15-7-2-5-13-6-3-10-19-17(13)15/h2-8,10,12,14,18H,9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485705 (3-(isoquinolin-5-yloxy)- N-methyl-3-(thiophen-2- y...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-12-19-10-7-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485711 ((S)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-2- ...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-16(17-8-4-12-21-17)20-15-7-2-6-14-13(15)5-3-10-19-14/h2-8,10,12,16,18H,9,11H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485713 ((S)-3-(isoquinolin-5- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-12-19-10-7-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485744 (3-(5-fluorothiophen-2-yl)- N-methyl-3-(quinolin-5-...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485747 (3-(5-fluorothiophen-2-yl)- 3-(isoquinolin-5-yloxy)...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485748 (3-(3-fluorothiophen-2-yl)- 3-(isoquinolin-5-yloxy)...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1sccc1F Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-11-20-9-5-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485752 ((S)-3-(5-fluorothiophen-2- yl)-3-(isoquinolin-5-yl...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485754 ((R)-3-(5-fluorothiophen-2- yl)-3-(isoquinolin-5-yl...) Show SMILES CNCC[C@@H](Oc1cccc2cnccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-11-20-10-7-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485755 ((R)-3-(5-fluorothiophen-2- yl)-N-methyl-3-(quinoli...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485758 (3-(isoquinolin-5-yloxy)-N- methyl-3-(thiophen-3- y...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1ccsc1 Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-11-19-9-5-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485764 ((R)-N-methyl-3-((1- methylisoquinolin-8- yl)oxy)-3...) Show SMILES CNCC[C@@H](Oc1cccc2ccnc(C)c12)c1cccs1 |r| Show InChI InChI=1S/C18H20N2OS/c1-13-18-14(8-11-20-13)5-3-6-16(18)21-15(9-10-19-2)17-7-4-12-22-17/h3-8,11-12,15,19H,9-10H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens)	BDBM485770 ((S)-3-(isoquinolin-5- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-11-19-9-5-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485780 ((S)-3-(5-Chlorothiophen-2-yl)-N-methyl-3-(quinolin...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccc(Cl)s1 |r| Show InChI InChI=1S/C17H17ClN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485755 ((R)-3-(5-fluorothiophen-2- yl)-N-methyl-3-(quinoli...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485753 ((S)-3-(5-fluorothiophen-2- yl)-N-methyl-3-(quinoli...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485758 (3-(isoquinolin-5-yloxy)-N- methyl-3-(thiophen-3- y...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1ccsc1 Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-11-19-9-5-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485759 (N-methyl-3-(quinolin-5- yloxy)-3-(thiophen-3- yl)p...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1ccsc1 Show InChI InChI=1S/C17H18N2OS/c1-18-10-7-16(13-8-11-21-12-13)20-17-6-2-5-15-14(17)4-3-9-19-15/h2-6,8-9,11-12,16,18H,7,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485760 (3-(isoquinolin-8-yloxy)-N- methyl-3-(thiophen-3- y...) Show SMILES CNCCC(Oc1cccc2ccncc12)c1ccsc1 Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-5-9-19-11-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485762 ((R)-3-(isoquinolin-5- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@@H](Oc1cccc2cnccc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-11-19-9-5-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485763 ((R)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@@H](Oc1cccc2ccncc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-8-6-16(14-7-10-21-12-14)20-17-4-2-3-13-5-9-19-11-15(13)17/h2-5,7,9-12,16,18H,6,8H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485774 (N-methyl-3-(quinolin-5- yloxy)-3-(thiazol-2- yl)pr...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1nccs1 Show InChI InChI=1S/C16H17N3OS/c1-17-9-7-15(16-19-10-11-21-16)20-14-6-2-5-13-12(14)4-3-8-18-13/h2-6,8,10-11,15,17H,7,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485777 (US10941138, Example 75) Show SMILES CNCCC(Oc1cccc2c(nccc12)C#N)c1cccs1 Show InChI InChI=1S/C18H17N3OS/c1-20-9-8-17(18-6-3-11-23-18)22-16-5-2-4-13-14(16)7-10-21-15(13)12-19/h2-7,10-11,17,20H,8-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485778 ((S)—N-Methyl-3-(quinolin-5-yloxy)-3-(thiazol-2-yl)...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1nccs1 |r| Show InChI InChI=1S/C16H17N3OS/c1-17-9-7-15(16-19-10-11-21-16)20-14-6-2-5-13-12(14)4-3-8-18-13/h2-6,8,10-11,15,17H,7,9H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485782 ((S)-3-(5-Fluorothiophen-2-yl)-3-(isoquinolin-8-ylo...) Show SMILES CNCC[C@@H](Oc1cccc2ccncc12)c1ccc(F)s1 |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-7-10-20-11-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485784 ((S)-3-(3-Fluorothiophen-2-yl)-3-(isoquinolin-5-ylo...) Show SMILES CNCC[C@H](Oc1cccc2cnccc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-11-20-9-5-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485788 ((S)-3-(3-Fluorothiophen-2-yl)-3-(isoquinolin-8-ylo...) Show SMILES CNCC[C@H](Oc1cccc2ccncc12)c1sccc1F |r| Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-5-9-20-11-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485790 ((R)-N-ethyl-3-(isoquinolin- 5-yloxy)-3-(thiophen-2...) Show SMILES CCNCC[C@@H](Oc1cccc2cnccc12)c1cccs1 |r| Show InChI InChI=1S/C18H20N2OS/c1-2-19-11-9-17(18-7-4-12-22-18)21-16-6-3-5-14-13-20-10-8-15(14)16/h3-8,10,12-13,17,19H,2,9,11H2,1H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485765 ((R)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-3- ...) Show SMILES CNCC[C@@H](Oc1cccc2ncccc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-10-7-16(13-8-11-21-12-13)20-17-6-2-5-15-14(17)4-3-9-19-15/h2-6,8-9,11-12,16,18H,7,10H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485769 ((S)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-3- ...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1ccsc1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-10-7-16(13-8-11-21-12-13)20-17-6-2-5-15-14(17)4-3-9-19-15/h2-6,8-9,11-12,16,18H,7,10H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485743 (3-(5-chlorothiophen-2-yl)- N-methyl-3-(quinolin-5-...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1ccc(Cl)s1 Show InChI InChI=1S/C17H17ClN2OS/c1-19-11-9-15(16-7-8-17(18)22-16)21-14-6-2-5-13-12(14)4-3-10-20-13/h2-8,10,15,19H,9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485748 (3-(3-fluorothiophen-2-yl)- 3-(isoquinolin-5-yloxy)...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1sccc1F Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-11-20-9-5-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485749 (3-(3-fluorothiophen-2-yl)- 3-(isoquinolin-8-yloxy)...) Show SMILES CNCCC(Oc1cccc2ccncc12)c1sccc1F Show InChI InChI=1S/C17H17FN2OS/c1-19-8-6-16(17-14(18)7-10-22-17)21-15-4-2-3-12-5-9-20-11-13(12)15/h2-5,7,9-11,16,19H,6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485750 (3-(3-fluorothiophen-2-yl)- N-methyl-3-(quinolin-5-...) Show SMILES CNCCC(Oc1cccc2ncccc12)c1sccc1F Show InChI InChI=1S/C17H17FN2OS/c1-19-10-7-16(17-13(18)8-11-22-17)21-15-6-2-5-14-12(15)4-3-9-20-14/h2-6,8-9,11,16,19H,7,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485751 (3-(5-fluorothiophen-2-yl)- 3-(isoquinolin-8-yloxy)...) Show SMILES CNCCC(Oc1cccc2ccncc12)c1ccc(F)s1 Show InChI InChI=1S/C17H17FN2OS/c1-19-9-8-15(16-5-6-17(18)22-16)21-14-4-2-3-12-7-10-20-11-13(12)14/h2-7,10-11,15,19H,8-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485705 (3-(isoquinolin-5-yloxy)- N-methyl-3-(thiophen-2- y...) Show SMILES CNCCC(Oc1cccc2cnccc12)c1cccs1 Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-12-19-10-7-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485712 ((S)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@H](Oc1cccc2ccncc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-7-10-19-12-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485715 ((R)-3-(isoquinolin-8- yloxy)-N-methyl-3- (thiophen...) Show SMILES CNCC[C@@H](Oc1cccc2ccncc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-9-8-16(17-6-3-11-21-17)20-15-5-2-4-13-7-10-19-12-14(13)15/h2-7,10-12,16,18H,8-9H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair

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