Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501863 (US11028067, Example 4) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.854 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501865 (US11028067, Example 6) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.99 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501860 (US11028067, Example 1 | US11028067, Example 8) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501866 (US11028067, Example 7) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501864 (US11028067, Example 5) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501860 (US11028067, Example 1 | US11028067, Example 8) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501861 (US11028067, Example 2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 56.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM501862 (US11028067, Example 3) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 558 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM501861 (US11028067, Example 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM501863 (US11028067, Example 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM501860 (US11028067, Example 1 | US11028067, Example 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM501865 (US11028067, Example 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM501862 (US11028067, Example 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM501866 (US11028067, Example 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM501864 (US11028067, Example 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Oblique Therapeutics AB US Patent | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65 | |||||||||||
More data for this Ligand-Target Pair |