Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [51-359]' and Ligand = 'BDBM282381'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-359] (Homo sapiens (Human))	BDBM282381 (2-(4-(3-amino-1H-pyrazolo [3,4-b]pyridin-5-yl) ben...) Show SMILES COc1cc(F)ccc1NC(=O)c1cc(cnc1NCc1ccc(cc1)-c1cnc2[nH]nc(N)c2c1)C(F)(F)F Show InChI InChI=1S/C27H21F4N7O2/c1-40-22-10-18(28)6-7-21(22)36-26(39)20-9-17(27(29,30)31)13-35-24(20)33-11-14-2-4-15(5-3-14)16-8-19-23(32)37-38-25(19)34-12-16/h2-10,12-13H,11H2,1H3,(H,33,35)(H,36,39)(H3,32,34,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc.; Millenium Pharmaceuticals, Inc. US Patent					Assay Description PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...				US Patent US10030016 (2018) BindingDB Entry DOI: 10.7270/Q2S46V16
					More data for this Ligand-Target Pair