Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50205901 ((R)-7,8-dichloro-1,3,4,10b-tetrahydropyrazino[2,1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 107 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cells | J Med Chem 50: 1365-79 (2007) Article DOI: 10.1021/jm0612968 BindingDB Entry DOI: 10.7270/Q2XP74M8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50205901 ((R)-7,8-dichloro-1,3,4,10b-tetrahydropyrazino[2,1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assay | J Med Chem 50: 1365-79 (2007) Article DOI: 10.1021/jm0612968 BindingDB Entry DOI: 10.7270/Q2XP74M8 | |||||||||||
More data for this Ligand-Target Pair |