Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM448438'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM448438 (US10695347, Compound I-4 | US10695347, Compound I-...) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccnc2S(=O)(=O)C(C)C)n1)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C28H36ClN7O4S/c1-19(2)41(37,38)27-24(5-4-10-30-27)32-26-22(29)18-31-28(34-26)33-23-7-6-21(17-25(23)39-3)35-11-8-20(9-12-35)36-13-15-40-16-14-36/h4-7,10,17-20H,8-9,11-16H2,1-3H3,(H2,31,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. US Patent					Assay Description 1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...				US Patent US10695347 (2020) BindingDB Entry DOI: 10.7270/Q2M90CQ8
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM448438 (US10695347, Compound I-4 | US10695347, Compound I-...) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccnc2S(=O)(=O)C(C)C)n1)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C28H36ClN7O4S/c1-19(2)41(37,38)27-24(5-4-10-30-27)32-26-22(29)18-31-28(34-26)33-23-7-6-21(17-25(23)39-3)35-11-8-20(9-12-35)36-13-15-40-16-14-36/h4-7,10,17-20H,8-9,11-16H2,1-3H3,(H2,31,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. US Patent					Assay Description 1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...				US Patent US10695347 (2020) BindingDB Entry DOI: 10.7270/Q2M90CQ8
					More data for this Ligand-Target Pair