Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor [L1196M]' and Ligand = 'BDBM179801'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM179801 (3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...) Show SMILES Fc1ccc(Cl)c(Sc2n[nH]c3ncc(cc23)-c2cnn(c2)C2CCNCC2)c1Cl Show InChI InChI=1S/C20H17Cl2FN6S/c21-15-1-2-16(23)17(22)18(15)30-20-14-7-11(8-25-19(14)27-28-20)12-9-26-29(10-12)13-3-5-24-6-4-13/h1-2,7-10,13,24H,3-6H2,(H,25,27,28)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	578	n/a	n/a	n/a	n/a	7.5	25
Tianjin University of Science and Technology					Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...				Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX
					More data for this Ligand-Target Pair