Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 2' and Ligand = 'BDBM369695'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM369695 (US10233156, Example I-235) Show SMILES C[C@@H](CO[C@H]1CC[C@@H](CC1)Oc1nc2c(F)c(F)c(F)c(F)c2n1C)NC(N)=O |r,wU:7.10,1.0,wD:4.3,(5.81,-2.65,;5.81,-1.11,;4.48,-.34,;3.14,-1.11,;1.81,-.34,;1.81,1.2,;.48,1.97,;-.86,1.2,;-.86,-.34,;.48,-1.11,;-2.19,1.97,;-3.52,1.2,;-3.69,-.33,;-5.19,-.65,;-5.96,-1.98,;-5.19,-3.32,;-7.5,-1.98,;-8.27,-3.32,;-8.27,-.65,;-9.81,-.65,;-7.5,.68,;-8.27,2.02,;-5.96,.68,;-4.93,1.83,;-5.33,3.32,;7.14,-.34,;8.48,-1.11,;9.81,-.34,;8.48,-2.65,)| Show InChI InChI=1S/C18H22F4N4O3/c1-8(24-17(23)27)7-28-9-3-5-10(6-4-9)29-18-25-15-13(21)11(19)12(20)14(22)16(15)26(18)2/h8-10H,3-7H2,1-2H3,(H3,23,24,27)/t8-,9-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description Recombinant human ACC1 and recombinant human ACC2, which were prepared by the method mentioned above, were preincubated with assay buffer solution (5...				J Med Chem 50: 641-62 (2007) BindingDB Entry DOI: 10.7270/Q2C53P4Z
					More data for this Ligand-Target Pair