Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM34651 (Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | 5.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... | Bioorg Med Chem 26: 3021-3029 (2018) Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN | |||||||||||
More data for this Ligand-Target Pair |