Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50359100'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359100 (CHEMBL1922815) Show SMILES NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1ccccc1F |(59.3,-8.57,;60.63,-9.35,;61.96,-8.58,;60.62,-10.89,;59.29,-11.65,;59.29,-13.19,;57.95,-13.95,;57.94,-15.49,;59.27,-16.26,;60.61,-15.5,;60.62,-13.95,;59.27,-17.8,;58.03,-18.71,;58.51,-20.18,;60.04,-20.17,;61.07,-21.31,;62.57,-20.99,;63.04,-19.52,;62.01,-18.38,;60.52,-18.7,;61.96,-11.66,;61.94,-13.2,;63.27,-13.97,;64.61,-13.21,;64.61,-11.67,;63.28,-10.89,;65.93,-13.99,;65.92,-15.53,;67.27,-13.23,;68.6,-14.01,;69.94,-13.25,;69.94,-11.72,;71.27,-10.95,;72.61,-11.73,;72.6,-13.27,;71.26,-14.03,;71.25,-15.57,)| Show InChI InChI=1S/C30H35FN4O2/c31-26-7-3-1-5-21(26)11-14-28(36)35-17-15-22(16-18-35)29(30(32)37)34-23-12-9-20(10-13-23)25-19-33-27-8-4-2-6-24(25)27/h1-8,11,14,19-20,22-23,29,33-34H,9-10,12-13,15-18H2,(H2,32,37)/b14-11+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human CCR2				Bioorg Med Chem Lett 21: 7496-501 (2011) Article DOI: 10.1016/j.bmcl.2011.09.113 BindingDB Entry DOI: 10.7270/Q22J6C9M
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359100 (CHEMBL1922815) Show SMILES NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1ccccc1F |(59.3,-8.57,;60.63,-9.35,;61.96,-8.58,;60.62,-10.89,;59.29,-11.65,;59.29,-13.19,;57.95,-13.95,;57.94,-15.49,;59.27,-16.26,;60.61,-15.5,;60.62,-13.95,;59.27,-17.8,;58.03,-18.71,;58.51,-20.18,;60.04,-20.17,;61.07,-21.31,;62.57,-20.99,;63.04,-19.52,;62.01,-18.38,;60.52,-18.7,;61.96,-11.66,;61.94,-13.2,;63.27,-13.97,;64.61,-13.21,;64.61,-11.67,;63.28,-10.89,;65.93,-13.99,;65.92,-15.53,;67.27,-13.23,;68.6,-14.01,;69.94,-13.25,;69.94,-11.72,;71.27,-10.95,;72.61,-11.73,;72.6,-13.27,;71.26,-14.03,;71.25,-15.57,)| Show InChI InChI=1S/C30H35FN4O2/c31-26-7-3-1-5-21(26)11-14-28(36)35-17-15-22(16-18-35)29(30(32)37)34-23-12-9-20(10-13-23)25-19-33-27-8-4-2-6-24(25)27/h1-8,11,14,19-20,22-23,29,33-34H,9-10,12-13,15-18H2,(H2,32,37)/b14-11+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica NV US Patent					Assay Description MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...				US Patent US8921559 (2014) BindingDB Entry DOI: 10.7270/Q270804M
					More data for this Ligand-Target Pair