BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50152165'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50152165
PNG
(CHEMBL186992 | [3-(6-Dimethylamino-4-methyl-pyridi...)
Show SMILES CCC(CC)Nc1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(6.49,3.73,;4.99,4.06,;3.97,2.89,;2.46,3.21,;1.97,4.67,;4.44,1.42,;3.43,.28,;3.9,-1.17,;2.88,-2.32,;3.37,-3.78,;1.38,-2.01,;.89,-.56,;-.51,.07,;-.35,1.61,;-1.51,2.61,;1.15,1.94,;1.92,.6,;-1.84,-.71,;-1.84,-2.25,;-3.17,-3.02,;-4.5,-2.25,;-4.5,-.71,;-3.17,.07,;-3.17,1.61,;-5.83,-3.02,;-7.18,-2.25,;-5.83,-4.56,)|
Show InChI InChI=1S/C21H30N6/c1-8-16(9-2)24-19-11-14(4)23-21-20(15(5)25-27(19)21)17-12-22-18(26(6)7)10-13(17)3/h10-12,16,24H,8-9H2,1-7H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 9.40n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor

J Med Chem 47: 4787-98 (2004)


Article DOI: 10.1021/jm040058e
BindingDB Entry DOI: 10.7270/Q2N29WDR
More data for this
Ligand-Target Pair