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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50017633'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50017633
PNG
(10-(4-Cyclopropylmethyl-piperazin-1-yl)-7-fluoro-2...)
Show SMILES Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(CC3CC3)CC2)n1 |c:14|
Show InChI InChI=1S/C19H23FN6/c1-24-12-15-18(23-24)21-16-5-4-14(20)10-17(16)22-19(15)26-8-6-25(7-9-26)11-13-2-3-13/h4-5,10,12-13H,2-3,6-9,11H2,1H3,(H,21,23)
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n/an/a 900n/an/an/an/an/an/a



Lilly Research Centre Limited

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to Dopamine receptor D2 from striatum of the rat brain

J Med Chem 32: 2573-82 (1989)


BindingDB Entry DOI: 10.7270/Q22F7P2J
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Ligand-Target Pair