Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50048299![]() (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description Tested for binding affinity towards rat striatal D2 receptor using [3H]-NPA as radioligand | J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50048299![]() (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437 | J Med Chem 38: 5007-14 (1996) BindingDB Entry DOI: 10.7270/Q2VQ31SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50048299![]() (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 25.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperone | J Med Chem 38: 5007-14 (1996) BindingDB Entry DOI: 10.7270/Q2VQ31SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50048299![]() (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligand | J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50048299![]() (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligand | J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50048299![]() (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum. | J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68 | |||||||||||
More data for this Ligand-Target Pair |