Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-3-phosphoglycerate dehydrogenase (Homo sapiens (Human)) | BDBM50519114 (CHEMBL4458393 | US11304929, Example 04-001) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH & Co. KG Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate... | J Med Chem 62: 7976-7997 (2019) Article DOI: 10.1021/acs.jmedchem.9b00718 BindingDB Entry DOI: 10.7270/Q25H7KNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-3-phosphoglycerate dehydrogenase (Homo sapiens (Human)) | BDBM50519114 (CHEMBL4458393 | US11304929, Example 04-001) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech... | Citation and Details BindingDB Entry DOI: 10.7270/Q2DR2ZP7 | |||||||||||
More data for this Ligand-Target Pair |