Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-beta (Homo sapiens (Human)) | BDBM50045004![]() (9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 4.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kansas University Curated by ChEMBL | Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone | J Med Chem 30: 2283-6 (1987) BindingDB Entry DOI: 10.7270/Q2R78HFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-beta (Homo sapiens (Human)) | BDBM50045004![]() (9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 2.32E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kansas University Curated by ChEMBL | Assay Description Binding affinity against sigma receptor | J Med Chem 30: 2283-6 (1987) BindingDB Entry DOI: 10.7270/Q2R78HFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-beta (Homo sapiens (Human)) | BDBM50045004![]() (9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sterling-Winthrop Research Institute Curated by ChEMBL | Assay Description Gyrase inhibitory activity against Escherichia coli | J Med Chem 31: 1694-7 (1988) BindingDB Entry DOI: 10.7270/Q2RX9F84 | |||||||||||
More data for this Ligand-Target Pair |