Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50041927'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Lactobacillus casei)	BDBM50041927 (5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...) Show SMILES Nc1nc(N)c2c3CCCCCCCCCCc3sc2n1 Show InChI InChI=1S/C16H24N4S/c17-14-13-11-9-7-5-3-1-2-4-6-8-10-12(11)21-15(13)20-16(18)19-14/h1-10H2,(H4,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase in Toxoplasma gondii.				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Rattus norvegicus (rat))	BDBM50041927 (5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...) Show SMILES Nc1nc(N)c2c3CCCCCCCCCCc3sc2n1 Show InChI InChI=1S/C16H24N4S/c17-14-13-11-9-7-5-3-1-2-4-6-8-10-12(11)21-15(13)20-16(18)19-14/h1-10H2,(H4,17,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of rat liver dihydrofolate reductase.				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Lactobacillus casei)	BDBM50041927 (5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...) Show SMILES Nc1nc(N)c2c3CCCCCCCCCCc3sc2n1 Show InChI InChI=1S/C16H24N4S/c17-14-13-11-9-7-5-3-1-2-4-6-8-10-12(11)21-15(13)20-16(18)19-14/h1-10H2,(H4,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Tested for inhibitory activity against dihydrofolate reductase in L. casei				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50041927 (5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...) Show SMILES Nc1nc(N)c2c3CCCCCCCCCCc3sc2n1 Show InChI InChI=1S/C16H24N4S/c17-14-13-11-9-7-5-3-1-2-4-6-8-10-12(11)21-15(13)20-16(18)19-14/h1-10H2,(H4,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase in pneumocystis carinii.				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair