Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50188083'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Escherichia coli)	BDBM50188083 (5-(1-(3,4,5-trimethoxyphenyl)ethyl)pyrimidine-2,4-...) Show SMILES COc1cc(cc(OC)c1OC)C(C)c1cnc(N)nc1N Show InChI InChI=1S/C15H20N4O3/c1-8(10-7-18-15(17)19-14(10)16)9-5-11(20-2)13(22-4)12(6-9)21-3/h5-8H,1-4H3,(H4,16,17,18,19)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago 60612 Curated by ChEMBL					Assay Description Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.				J Med Chem 39: 4825-32 (1996) Article DOI: 10.1021/jm960491r BindingDB Entry DOI: 10.7270/Q2668GXG
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50188083 (5-(1-(3,4,5-trimethoxyphenyl)ethyl)pyrimidine-2,4-...) Show SMILES COc1cc(cc(OC)c1OC)C(C)c1cnc(N)nc1N Show InChI InChI=1S/C15H20N4O3/c1-8(10-7-18-15(17)19-14(10)16)9-5-11(20-2)13(22-4)12(6-9)21-3/h5-8H,1-4H3,(H4,16,17,18,19)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago 60612 Curated by ChEMBL					Assay Description Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.				J Med Chem 39: 4825-32 (1996) Article DOI: 10.1021/jm960491r BindingDB Entry DOI: 10.7270/Q2668GXG
					More data for this Ligand-Target Pair