Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM358![]() ((2R,3R,4R,5R)-2,5-bis(benzyloxy)-3,4-dihydroxy-N,N...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.200 | -56.3 | n/a | n/a | n/a | n/a | n/a | 5.0 | 30 |
Uppsala University | Assay Description A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid... | Eur J Biochem 270: 1746-58 (2003) Article DOI: 10.1046/j.1432-1033.2003.03533.x BindingDB Entry DOI: 10.7270/Q2NZ85WX | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM358![]() ((2R,3R,4R,5R)-2,5-bis(benzyloxy)-3,4-dihydroxy-N,N...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.600 | -53.5 | n/a | n/a | n/a | n/a | n/a | 5.0 | 30 |
Stockholm University | Assay Description A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid... | J Med Chem 44: 3407-16 (2001) Article DOI: 10.1021/jm0011171 BindingDB Entry DOI: 10.7270/Q2862DND | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM358![]() ((2R,3R,4R,5R)-2,5-bis(benzyloxy)-3,4-dihydroxy-N,N...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.22 | -51.7 | n/a | n/a | n/a | n/a | n/a | 5.0 | 30 |
Linkoping University | Assay Description A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid... | J Med Chem 44: 3083-91 (2001) Article DOI: 10.1021/jm001134q BindingDB Entry DOI: 10.7270/Q2DZ06GR | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |