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Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM361'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM361
PNG
((2R,3R,4R,5R)-2,5-bis[(4-fluorophenyl)methoxy]-3,4...)
Show SMILES O[C@H]([C@@H](O)[C@@H](OCc1ccc(F)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)[C@@H](OCc1ccc(F)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |r|
Show InChI InChI=1S/C38H38F2N2O8/c39-25-13-9-21(10-14-25)19-49-35(37(47)41-31-27-7-3-1-5-23(27)17-29(31)43)33(45)34(46)36(50-20-22-11-15-26(40)16-12-22)38(48)42-32-28-8-4-2-6-24(28)18-30(32)44/h1-16,29-36,43-46H,17-20H2,(H,41,47)(H,42,48)/t29-,30-,31+,32+,33-,34-,35-,36-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5.39 -48.0n/an/an/an/an/a5.030



Linkoping University



Assay Description
A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...

J Med Chem 44: 3083-91 (2001)


Article DOI: 10.1021/jm001134q
BindingDB Entry DOI: 10.7270/Q2DZ06GR
More data for this
Ligand-Target Pair