Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1' and Ligand = 'BDBM385075'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2F76HN2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2FB56W4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...				J Med Chem 51: 7049-52 (2008) BindingDB Entry DOI: 10.7270/Q2RJ4MTP
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2ZG6X5T
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q243DZ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q24X5CXQ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2H99949
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM385075 (US10287258, Example 35 | US10669245, Example 35 | ...) Show SMILES CN1C(=O)CNc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-29-21-12-18(7-8-20(21)27-15-23(29)30)17-5-3-16(4-6-17)11-19(13-25)28-24(31)22-14-26-9-2-10-32-22/h3-8,12,19,22,26-27H,2,9-11,14-15H2,1H3,(H,28,31)/t19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
ASTRAZENECA AB US Patent					Assay Description The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...				US Patent US10669245 (2020) BindingDB Entry DOI: 10.7270/Q2862KG7
					More data for this Ligand-Target Pair