Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM50104975![]() ((8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-bip...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Inhibition of porcine TNF-alpha converting enzyme(pTACE). | J Med Chem 44: 3351-4 (2001) BindingDB Entry DOI: 10.7270/Q2VD6XRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM50104975![]() ((8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-bip...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens Curated by ChEMBL | Assay Description Inhibition of pig TACE | Bioorg Med Chem 16: 8781-94 (2008) Article DOI: 10.1016/j.bmc.2008.08.058 BindingDB Entry DOI: 10.7270/Q2JD4WM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM50104975![]() ((8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-bip...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of porcine TACE | Bioorg Med Chem Lett 13: 4293-7 (2003) BindingDB Entry DOI: 10.7270/Q2T72GV7 | |||||||||||
More data for this Ligand-Target Pair |