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Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50240575'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50240575
PNG
(CHEMBL4089245)
Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3c(C)cccc3NC(=O)C=C)nc2)c1F
Show InChI InChI=1S/C23H22F2N4O4/c1-5-19(30)28-16-8-6-7-13(2)22(16)29-23-26-10-14(11-27-23)33-12-15-20(24)17(31-3)9-18(32-4)21(15)25/h5-11H,1,12H2,2-4H3,(H,28,30)(H,26,27,29)
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



WuXi AppTec (Shanghai) Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex

Bioorg Med Chem Lett 27: 2420-2423 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.014
BindingDB Entry DOI: 10.7270/Q2M90BT6
More data for this
Ligand-Target Pair