Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor [L858R] (Homo sapiens (Human)) | BDBM195873 (US9670213, Compound 018 N-(3-(2-(4-morpholinopheny...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.83 | n/a | n/a | n/a | n/a | n/a | 25 |
East China University of Science and Technology US Patent | Assay Description In vitro enzyme activity assay: wild-type and various mutants (T790M, L858R, L861Q, L858 R/T790M) EGFR, Z′-Lyte Kinase Assay Kit were purchased... | US Patent US9670213 (2017) BindingDB Entry DOI: 10.7270/Q23R0R1P | |||||||||||
More data for this Ligand-Target Pair |